Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
Nicotine Patch · 1 trial · 1 indication
Statistical power will focus on primary objective. Primary analyses use intention-to-treat (ITT) principles, with missing observations imputed as smoking.
| Arm | Type | Description |
|---|---|---|
| Quitline (QL) Group | EXPERIMENTAL | Questionnaires completed at baseline and at 6 weeks, 12 weeks, and 6 months after the CT scan. CO level measured at baseline and at 6 weeks, 12 weeks, and 6 months after the CT scan. Participants have a CT scan of chest to look for signs of lung cancer. Participants watch a short video about lung cancer, CT scans, and smoking cessation. Brief cessation counseling given by LDCT provider. Participants given shared decision making and discussion about screening with the LDCT provider. Participants referred to the Quitline for counseling and NRT (nicotine patch). Participants have 5 smoking cessation counseling sessions over the next 12 weeks. |
| Quitline-Rx (QL-Rx) Group | EXPERIMENTAL | Questionnaires completed at baseline and at 6 weeks, 12 weeks, and 6 months after the CT scan. CO level measured at baseline and at 6 weeks, 12 weeks, and 6 months after the CT scan. Participants have a CT scan of chest to look for signs of lung cancer. Participants watch a short video about lung cancer, CT scans, and smoking cessation. Brief cessation counseling given by LDCT provider. LDCT provider and patient discuss options for pharmacotherapy. Participants referred to the Quitline for counseling. Participants have 5 smoking cessation counseling sessions over the next 12 weeks. |
| Integrated Care (IC) Group | EXPERIMENTAL | Questionnaires completed at baseline and at 6 weeks, 12 weeks, and 6 months after the CT scan. CO level measured at baseline and at 6 weeks, 12 weeks, and 6 months after the CT scan. Participants have a CT scan of chest to look for signs of lung cancer. Participants watch a short video about lung cancer, CT scans, and smoking cessation. Brief cessation counseling given by LDCT provider. Participant referred to Tobacco Treatment Program (TTP). TTP provides 4-8 counseling sessions and pharmacotherapy over a 10-12 week period, |
| Name | Type | Description |
|---|---|---|
| Questionnaires | BEHAVIORAL | Questionnaires completed at baseline and at 6 weeks, 12 weeks, and 6 months after the CT scan. |
| Low Dose Computed Tomography Scan | PROCEDURE | Participants have a CT scan of chest to look for signs of lung cancer. |
| Shared Decision Making + Video | OTHER | Participants given shared decision making and discussion about screening with the LDCT provider. Participants watch a short video about lung cancer, CT scans, and smoking cessation. |
| Cessation Counseling | BEHAVIORAL | Brief cessation counseling given by LDCT provider. |
| Quitline | BEHAVIORAL | Participants referred to the Quitline for counseling. Participants have 5 smoking cessation counseling sessions over the next 12 weeks. |
| Pharmacotherapy Discussion | BEHAVIORAL | Participant informed of the risk, benefits and relative efficacy of cessation medications and to assess their medication preferences, expectations and medical suitability for either option. At the conclusion of this conversation the patient is provided with an initial supply of the medication jointly decided between provider and patient. |
| Nicotine Patch | DRUG | Nicotine patch dispensed. Dosing at physician's discretion. |
| Anti-Smoking Drug | DRUG | Varenicline or Buproprion prescribed by study doctor with directions of when and how much of anti-smoking drug that should be taken each time. |
| Tobacco Treatment Program | BEHAVIORAL | Participant referred to Tobacco Treatment Program (TTP). TTP provides 4-8 counseling sessions and pharmacotherapy over a 10-12 week period, |
| Carbon Monoxide (CO) Level Test | OTHER | Participant asked to blow air through a CO-measuring device. |
Inclusion Criteria: * Age: 50 or older * Meets guidelines for lung cancer screening, as determined by radiology team * Reports being a daily or non-daily smoker (any self-reported smoking in the past 30days) and is interested in treatment that might change smoking behavior. * Able to follow verbal ...