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NMDA Antagonist, CP-101, 606

Phase 2

Depressive Disorder, Major | Small molecule | Psychiatry |Pfizer, Inc.|Last Updated: Sep 22, 2006

Target and mechanism

ModalitySmall molecule

Also known as NMDA Antagonist, CP-101,606 (traxoprodil)

Success Probability

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Market & Valuation

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Trial Design

RandomizedUNCONTROLLED
Total Trials1
Total Enrollment30

FDA Designations

No designations recorded

Clinical trial landscape

NMDA Antagonist, CP-101, 606 · 1 trial · 1 indication

Phase 2 1
NCT00163059The Antidepressant Effects Of The NMDA Antagonist, CP-101,606, In Patients With MDDDepressive Disorder, Major
COMPLETED30 Analytics
PHASE2COMPLETED
The Antidepressant Effects Of The NMDA Antagonist, CP-101,606, In Patients With MDD
Depressive Disorder, MajorUnlock trial analytics

Study Endpoints

Primary Endpoints

MADRS

Secondary Endpoints

HAM-D
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Study Design & Arms

AllocationRANDOMIZED
MaskingSINGLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
NMDA Antagonist, CP-101,606 (traxoprodil)DRUG -
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Eligibility Criteria

Age Range18 Years to 55 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Primary DSM-IV diagnosis of MDD Exclusion Criteria: * Subjects with evidence or history of clinically significant hematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, psychiatric, neurologic, or allergic disease (including drug allergies, bu...

Countries:United States
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Frequently asked questions about NMDA Antagonist, CP-101, 606

What is NMDA Antagonist, CP-101,606?

NMDA Antagonist, CP-101,606 is an investigational small molecule developed by Pfizer, Inc. (ticker PFE) for major depressive disorder. It is also known as traxoprodil. It has been studied in a Phase 2 clinical trial and is not an approved treatment.

What is NMDA Antagonist, CP-101,606 used for?

NMDA Antagonist, CP-101,606 was studied for the treatment of major depressive disorder, a condition in the psychiatry therapeutic area. The clinical research evaluated its antidepressant effects in adult patients with MDD. It is an investigational agent and has not been approved for any use.

Who makes NMDA Antagonist, CP-101,606?

Pfizer, Inc., which trades under the ticker PFE, is the developer of NMDA Antagonist, CP-101,606. Pfizer sponsored the clinical research program for this compound in major depressive disorder.

What phase is NMDA Antagonist, CP-101,606 in?

NMDA Antagonist, CP-101,606 is in Phase 2 development. One Phase 2 trial has been completed, and no trials are currently active. The compound remains investigational and has not received FDA approval for major depressive disorder or any other indication.

What clinical trials is NMDA Antagonist, CP-101,606 in?

NMDA Antagonist, CP-101,606 was evaluated in a single completed Phase 2 study, NCT00163059, titled The Antidepressant Effects Of The NMDA Antagonist, CP-101,606, In Patients With MDD. The trial enrolled 30 adults with major depressive disorder in the United States and used a randomized, uncontrolled design.

Is NMDA Antagonist, CP-101,606 the same as traxoprodil?

Yes, NMDA Antagonist, CP-101,606 is also known as traxoprodil. Both names refer to the same Pfizer small molecule compound studied in Phase 2 for major depressive disorder. Searches for either name point to the same investigational asset.