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NMDA Antagonist, CP-101,606

Phase 2

Depressive Disorder, Major | Small molecule | Other |Pfizer, Inc.|Last Updated: Sep 22, 2006

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedUNCONTROLLED
Total Trials1
Total Enrollment30
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00163059The Antidepressant Effects Of The NMDA Antagonist, CP-101,606, In Patients With MDDPHASE2 COMPLETED 30May 1, 2004Dec 1, 2005Sep 22, 20061 United States
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Study Endpoints
Primary Endpoints
MADRS
Secondary Endpoints
HAM-D
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Study Design & Arms
AllocationRANDOMIZED
MaskingSINGLE
ModelPARALLEL
PurposeTREATMENT
Interventions
NameTypeDescription
NMDA Antagonist, CP-101,606 (traxoprodil)DRUG -
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Eligibility Criteria
Age Range18 Years — 55 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Primary DSM-IV diagnosis of MDD Exclusion Criteria: * Subjects with evidence or history of clinically significant hematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, psychiatric, neurologic, or allergic disease (including drug allergies, bu...

Countries:United States
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