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MnB rLP2086

Phase 1

Meningitis, Meningococcal | Monoclonal antibody | Infectious Disease |Pfizer, Inc.|Last Updated: Dec 5, 2007

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment108

FDA Designations

No designations recorded

Clinical trial landscape

MnB rLP2086 · 1 trial · 1 indication

Phase 1 1
NCT00297687Study Evaluating the Safety, Immunogenicity and Tolerability of Meningococcal Group B Vaccine in Healthy AdultsMeningitis, Meningococcal
COMPLETED108 Analytics
PHASE1COMPLETED
Study Evaluating the Safety, Immunogenicity and Tolerability of Meningococcal Group B Vaccine in Healthy Adults
Meningitis, MeningococcalUnlock trial analytics

Study Endpoints

Primary Endpoints

Local & systemic safety throughout the trial

Secondary Endpoints

Evidence of an immune response 1 month after dose 2 & 1 month after dose 3
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposePREVENTION

Interventions

NameTypeDescription
MnB rLP2086BIOLOGICAL -
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Eligibility Criteria

Age Range18 Years to 25 Years
SexALL
Healthy VolunteersYes
Study Sites3

Inclusion Criteria: * Healthy 18-25 year olds Exclusion Criteria: * Prior history of vaccination with any meningococcal vaccine * Prior history of any invasive meningococcal disease

Countries:Australia
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Frequently asked questions about MnB rLP2086

What is MnB rLP2086 used for?

MnB rLP2086 is an investigational vaccine being studied for the prevention of meningitis and meningococcal disease. It is a meningococcal group B vaccine candidate developed by Pfizer, Inc. (PFE). The drug is currently in Phase 1 clinical development and has not been approved by regulatory authorities.

Who makes MnB rLP2086?

MnB rLP2086 is being developed by Pfizer, Inc. (PFE), a multinational pharmaceutical company. The drug is an investigational meningococcal group B vaccine candidate intended for the prevention of meningitis and meningococcal disease. It is currently in Phase 1 clinical development.

What phase is MnB rLP2086 in?

MnB rLP2086 is in Phase 1 clinical development. It is an investigational vaccine candidate for meningitis and meningococcal disease, developed by Pfizer, Inc. (PFE). The drug has not been approved and remains in early-stage clinical testing.

What clinical trials is MnB rLP2086 in?

MnB rLP2086 has been studied in one completed Phase 1 clinical trial, NCT00297687, titled 'Study Evaluating the Safety, Immunogenicity and Tolerability of Meningococcal Group B Vaccine in Healthy Adults.' The trial enrolled 108 healthy adult participants in Australia and was completed.

Is MnB rLP2086 a monoclonal antibody?

MnB rLP2086 is classified as a monoclonal antibody modality, but it is being developed as a meningococcal group B vaccine candidate. It is intended to prevent meningitis and meningococcal disease. The drug is in Phase 1 clinical development by Pfizer, Inc. (PFE).