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MRE0094

Phase 2

Foot Ulcer, Diabetic | Small molecule | Metabolic |Pfizer, Inc.|Last Updated: Jun 1, 2012

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment322

FDA Designations

No designations recorded

Clinical trial landscape

MRE0094 · 1 trial · 2 indications

Phase 2 1
NCT00312364Safety and Efficacy Study of MRE0094 to Treat Chronic, Neuropathic, Diabetic Foot UlcersFoot Ulcer, Diabetic
COMPLETED322 Analytics
PHASE2COMPLETED
Safety and Efficacy Study of MRE0094 to Treat Chronic, Neuropathic, Diabetic Foot Ulcers
Foot Ulcer, DiabeticUnlock trial analytics

Study Endpoints

Primary Endpoints

Incidence of complete healing of target ulcer at endpoint or 90 days, whichever is earlier.

Secondary Endpoints

Time to closure and percent reduction in surface area of the target ulcer.
Incidence, intensity, and seriousness of adverse events. Changes in irritation scores.
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
MRE0094DRUG -
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Eligibility Criteria

Age Range18 Years to 85 Years
SexALL
Healthy VolunteersNo
Study Sites63

Inclusion Criteria: Participants included in the study must: * Have type 1 or type 2 diabetes mellitus. * Have problems with the nerves in their feet. * Have an ulcer on the bottom surface of their foot that has been present for 3 weeks or more and is of sufficient size to qualify for the study. *...

Countries:United States
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Frequently asked questions about MRE0094

What is MRE0094 used for?

MRE0094 is an investigational small molecule being studied for the treatment of diabetic foot ulcers, specifically chronic, neuropathic diabetic foot ulcers. It is being developed by Pfizer, Inc. and is intended to address complications of diabetes, including foot ulcers that are difficult to heal.

Who makes MRE0094?

MRE0094 is being developed by Pfizer, Inc., a pharmaceutical company traded on the New York Stock Exchange under the ticker symbol PFE. The drug is an investigational small molecule in clinical development for diabetic foot ulcers.

What phase is MRE0094 in?

MRE0094 is in Phase 2 clinical development. It is an investigational drug, meaning it has not been approved by regulatory authorities and is still being studied for safety and efficacy in patients with diabetic foot ulcers.

What clinical trials is MRE0094 in?

MRE0094 has one completed Phase 2 clinical trial, identified by the National Clinical Trial number NCT00312364. The trial, titled 'Safety and Efficacy Study of MRE0094 to Treat Chronic, Neuropathic, Diabetic Foot Ulcers,' enrolled 322 participants in the United States and was a randomized, double-blind study.

Is MRE0094 the same as any other drug?

MRE0094 is the primary name used for this investigational drug in clinical trials. No alternative names have been reported in the available clinical trial information, so it is not known to be the same as any other marketed or investigational drug.