Recent Updates
Recently added Catalysts

MAC-321

Phase 2

Carcinoma, Non-Small-Cell Lung | Small molecule | Oncology |Pfizer, Inc.|Trials Updated: Aug 21, 2009

MAC-321 development status

Highest phase Phase 2
Registered trials 2 across 1 sponsor since Jun 2003

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

UNCONTROLLED
Total Trials2
Total Enrollment93

FDA Designations

No designations recorded

MAC-321 clinical trials

MAC-321 · 2 trials · 5 indications

Phase 2 2
NCT00063219Study Evaluating MAC-321 in Non-small Cell Lung Cancer Refractory to Platinum-based TherapyCarcinoma, Non-Small-Cell Lung
COMPLETED48 Analytics
NCT00063427Study Evaluating MAC-321 in Colorectal CancerColorectal Neoplasms
COMPLETED45 Analytics
PHASE2COMPLETED
Study Evaluating MAC-321 in Non-small Cell Lung Cancer Refractory to Platinum-based Therapy
Carcinoma, Non-Small-Cell LungUnlock trial analytics
PHASE2COMPLETED
Study Evaluating MAC-321 in Colorectal Cancer
Colorectal NeoplasmsUnlock trial analytics

Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
PurposeTREATMENT

Interventions

NameTypeDescription
MAC-321DRUG -
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites13

Inclusion Criteria: * Recurrence of non-small cell lung cancer after at least 1 prior chemotherapy regimen containing a platinum agent * Recovery from all acute side effects of prior therapies (with the exception of hair loss) * Adequate bone marrow, liver, and kidney function Exclusion Criteria: ...

Countries:United States
Unlock Eligibility Criteria

Frequently asked questions about MAC-321

What is MAC-321 used for?

MAC-321 is an investigational small molecule being studied in oncology for the treatment of carcinoma, non-small-cell lung cancer, and colorectal neoplasms. It has been evaluated in Phase 2 clinical trials for these indications.

Who makes MAC-321?

MAC-321 is being developed by Pfizer, Inc., a biopharmaceutical company traded on the New York Stock Exchange under the ticker symbol PFE.

What phase is MAC-321 in?

MAC-321 is in Phase 2 clinical development. It is an investigational drug and has not been approved by regulatory authorities for any use.

What clinical trials is MAC-321 in?

MAC-321 has been studied in two completed Phase 2 trials: NCT00063219 in non-small cell lung cancer refractory to platinum-based therapy and NCT00063427 in colorectal cancer. Both trials are completed.

Is MAC-321 the same as any other drug?

No alternative names for MAC-321 have been identified in the available information. It is referred to solely as MAC-321 in clinical trial records.