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Isovorin

Phase 3

Colon Cancer | Small molecule | Oncology |Pfizer, Inc.|Last Updated: Aug 13, 2009

Success Probability

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Market & Valuation

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Trial Design

RandomizedUNCONTROLLED
Total Trials1
Total Enrollment650

FDA Designations

No designations recorded

Clinical trial landscape

Isovorin · 2 trials · 2 indications

Phase 3 2
NCT00195585Study Evaluating Isovorin in Colon CancerColon Cancer
COMPLETED650 Analytics
NCT00195572Study Evaluating Isovorin in Advanced/Recurrent Gastric CancerGastric Cancer
COMPLETED200 Analytics
PHASE3COMPLETED
Study Evaluating Isovorin in Colon Cancer
Colon CancerUnlock trial analytics
PHASE3COMPLETED
Study Evaluating Isovorin in Advanced/Recurrent Gastric Cancer
Gastric CancerUnlock trial analytics

Study Endpoints

Primary Endpoints

Relapse-free survival time
Survival time

Secondary Endpoints

Disease-free survival time, survival time, safety
Response rate, duration of response, time to progression, safety, quality of life
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
IsovorinDRUG -
UFTDRUG -
TS-1DRUG -
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Eligibility Criteria

Age Range20 Years to 75 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Dukes C, Cure A colon cancer diagnosed histologically or cytologically * Normal organ function of bone marrow, heart, liver and kidney * Age 20-75 Other inclusion applies Exclusion Criteria: * Serious bone marrow suppression, infection, heart disease or complication * Famil...

Countries:Japan
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Frequently asked questions about Isovorin

What is Isovorin used for?

Isovorin is an investigational small molecule being studied for the treatment of gastric cancer and colon cancer. It is developed by Pfizer, Inc. (NYSE: PFE) and is currently in Phase 3 clinical development for these oncology indications.

Who makes Isovorin?

Isovorin is developed by Pfizer, Inc., a biopharmaceutical company traded on the New York Stock Exchange under the ticker symbol PFE. The drug is being investigated for use in gastric cancer and colon cancer.

What phase is Isovorin in?

Isovorin is in Phase 3 clinical development. It is an investigational drug, meaning it has not been approved by regulatory authorities and is still being studied in clinical trials for the treatment of gastric cancer and colon cancer.

What clinical trials is Isovorin in?

Isovorin has been studied in two completed Phase 3 trials. NCT00195572 evaluated Isovorin in advanced or recurrent gastric cancer with 200 participants in Japan. NCT00195585 evaluated Isovorin in colon cancer with 650 participants in Japan. Both trials enrolled adults aged 20 years and older.

Is Isovorin the same as leucovorin?

Isovorin is a form of folinic acid, also known as leucovorin. It is a small molecule used as a rescue agent in cancer chemotherapy. The drug is being developed by Pfizer, Inc. for the treatment of gastric and colon cancers.