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Effexor

Phase 3

Depression | Small molecule | Psychiatry |Pfizer, Inc.|Last Updated: May 28, 2007

Success Probability

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Market & Valuation

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Trial Design

Double-BlindUNCONTROLLED
Total Trials3
Total Enrollment840

FDA Designations

No designations recorded

Clinical trial landscape

Effexor · 3 trials · 1 indication

Phase 3 3
NCT00225524Study Evaluating Long-Term Safety of Effexor XR in Patients With Major Depression.Depression
COMPLETED150 Analytics
NCT00225511Study Evaluating Effexor XR for Major Depression.Depression
COMPLETED590 Analytics
NCT00225485Study Evaluating Effexor XR in Elderly Patients With Major Depression.Depression
COMPLETED100 Analytics
PHASE3COMPLETED
Study Evaluating Long-Term Safety of Effexor XR in Patients With Major Depression.
DepressionUnlock trial analytics
PHASE3COMPLETED
Study Evaluating Effexor XR for Major Depression.
DepressionUnlock trial analytics
PHASE3COMPLETED
Study Evaluating Effexor XR in Elderly Patients With Major Depression.
DepressionUnlock trial analytics

Study Endpoints

Primary Endpoints

Incidence of adverse events
Response rate of HAM-D17 (Hamilton Rating Scale for Depression) at the final-on-therapy.
Response rate of HAM-D17 (Hamilton Rating Scale for Depression) at the final-on-therapy

Secondary Endpoints

Quantitative data for laboratory data
Difference of total score of HAM-D17 between baseline and final-on-therapy.
Remission rate of HAM-D17 at the final-on-therapy.
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
Effexor XRDRUG -
MilnacipranDRUG -
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Eligibility Criteria

Age Range20 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites73

Inclusion Criteria: * Patients who complete the Phase III double-blind study (Protocol Number 0600B1-816) Exclusion Criteria: * Patients with schizophrenia or any other psychotic disorder * Patients with history or presence of bipolar disorder

Countries:Japan
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Frequently asked questions about Effexor

What is Effexor used for?

Effexor is used for the treatment of depression. It is a small molecule being developed by Pfizer, Inc. for this psychiatric condition. The drug has been studied in Phase 3 clinical trials, all of which have been completed, with a total enrollment of 840 patients across three studies.

Who makes Effexor?

Effexor is developed by Pfizer, Inc., which trades under the ticker symbol PFE. The company has conducted Phase 3 clinical trials for Effexor in the treatment of depression. All three trials have been completed, with no active trials currently ongoing.

What phase is Effexor in?

Effexor is in Phase 3 clinical development for depression. All three Phase 3 trials have been completed, and there are no active trials currently enrolling. The drug is investigational and has not been reported as approved based on the available data.

What clinical trials is Effexor in?

Effexor has been studied in three completed Phase 3 clinical trials: NCT00225485, a study in elderly patients with major depression; NCT00225511, a study for major depression; and NCT00225524, a long-term safety study. All trials were conducted in Japan and enrolled a total of 840 patients.

Is Effexor FDA approved?

Based on the available data, Effexor is an investigational drug that has completed Phase 3 clinical trials for depression. The information does not indicate that it has received FDA approval. It remains in clinical development, with all trials completed and no active studies ongoing.