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CP-866, 087

Phase 2

Alcoholism | Small molecule | Psychiatry |Pfizer, Inc.|Last Updated: Oct 2, 2012

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment88

FDA Designations

No designations recorded

Clinical trial landscape

CP-866, 087 · 3 trials · 3 indications

Phase 2 3
NCT00482664The Efficacy, Safety And Toleration Of CP-866,087 In Pre-Menopausal Women With Female Sexual Arousal Disorder.Sexual Dysfunction, Physiological
COMPLETED84 Analytics
NCT00479492Study To Determine The Effects And Safety Of A Weight Loss Compound On Overweight, Otherwise Healthy, VolunteersObesity
COMPLETED94 Analytics
NCT00147576Study To Examine Effect Of CP-866,087 On Consumption And Craving Of Alcohol In Alcohol Dependent Subjects.Alcoholism
COMPLETED88 Analytics
PHASE2COMPLETED
The Efficacy, Safety And Toleration Of CP-866,087 In Pre-Menopausal Women With Female Sexual Arousal Disorder.
Sexual Dysfunction, Physiological
NCT0048266484
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PHASE2COMPLETED
Study To Determine The Effects And Safety Of A Weight Loss Compound On Overweight, Otherwise Healthy, Volunteers
Obesity
NCT0047949294
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PHASE2COMPLETED
Study To Examine Effect Of CP-866,087 On Consumption And Craving Of Alcohol In Alcohol Dependent Subjects.
Alcoholism
NCT0014757688
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Study Endpoints

Primary Endpoints

Diary events, including Satisfactory Sexual Experiences (SSEs) over 6 weeks.
6 weeks
Score in Abbreviated Sexual Function Questionnaire after 6 weeks of treatment.
6 weeks
Measure the effect of weight loss over 12 weeks in overweight otherwise healthy patients. Measurements will include body weight and waist circumference. Measurements will occur at Day 1, 7, 14, 28, 42, 56, 70, 84 and 94.
94 days
The amount of alcohol consumed will be based on the total number of standardized drinks consumed during a two-hour laboratory-based self-administration procedure following 7 days of treatment with study medication.

Secondary Endpoints

Exit interview at end of study. Meaningful Benefit Question at end of study.
End of study
Measure of Female Sexual Distress questionnaire after 6 weeks of treatment.
6 weeks
To characterize the effect of 4 weeks of dosing of 3 different doses of CP-866,087 on 24-hour urinary cortisol levels. Measured at Day 1 and Day 29
29 days
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelCROSSOVER
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1 mgEXPERIMENTAL -
10 mgEXPERIMENTAL -
3 mgEXPERIMENTAL -
PlaceboPLACEBO_COMPARATOR -
1EXPERIMENTAL -
2EXPERIMENTAL -
3EXPERIMENTAL -
4PLACEBO_COMPARATOR -

Interventions

NameTypeDescription
CP-866,087DRUGTablets for oral administration
PlaceboDRUGTablets for oral administration
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Eligibility Criteria

Age Range20 Years to 45 Years
SexFEMALE
Healthy VolunteersNo
Study Sites12

Inclusion Criteria: * healthy pre-menopausal women * primary female sexual arousal disorder causing distress * on stable use of oral contraceptives Exclusion Criteria: * any other significant disease causing Female Sexual Dysfunction including psychiatric disease * subjects on drugs known to caus...

Countries:AustraliaDenmarkNorwaySouth AfricaSwedenUnited States
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Frequently asked questions about CP-866, 087

What is CP-866,087 used for?

CP-866,087 is an investigational small molecule being studied for alcoholism, physiological sexual dysfunction, and obesity. It is being developed by Pfizer, Inc. (PFE) and has completed Phase 2 clinical trials in these indications.

What does CP-866,087 target?

CP-866,087 is a small molecule being developed by Pfizer, Inc. (PFE) for psychiatric and metabolic conditions. Its specific molecular target has not been disclosed in available clinical trial information.

Who makes CP-866,087?

CP-866,087 is being developed by Pfizer, Inc. (PFE). The company has sponsored Phase 2 clinical trials evaluating the drug for alcoholism, obesity, and physiological sexual dysfunction.

What phase is CP-866,087 in?

CP-866,087 is in Phase 2 clinical development. It has completed three Phase 2 trials, and no active trials are currently listed. The drug is investigational and has not been approved by regulatory authorities.

What clinical trials is CP-866,087 in?

CP-866,087 has completed three Phase 2 trials: NCT00147576 in alcoholism (88 participants), NCT00479492 in obesity (94 participants), and NCT00482664 in female sexual arousal disorder (84 participants). All trials are completed.

Is CP-866,087 the same as other drugs?

CP-866,087 is not known to have alternative names. It is a distinct investigational compound developed by Pfizer, Inc. (PFE) for alcoholism, obesity, and physiological sexual dysfunction.