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CI-1033

Phase 2

Breast Neoplasms | Small molecule | Oncology |Pfizer, Inc.|Last Updated: May 4, 2007

Success Probability

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Market & Valuation

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Trial Design

RandomizedUNCONTROLLED
Total Trials1
Total Enrollment168

FDA Designations

No designations recorded

Clinical trial landscape

CI-1033 · 1 trial · 1 indication

Phase 2 1
NCT00051051A Phase II Study of CI-1033 in Treating Patients With Metastatic (Stage IV) Breast CancerBreast Neoplasms
COMPLETED168 Analytics
PHASE2COMPLETED
A Phase II Study of CI-1033 in Treating Patients With Metastatic (Stage IV) Breast Cancer
Breast NeoplasmsUnlock trial analytics

Study Endpoints

Primary Endpoints

The primary objective is to assess the antitumor activity of CI 1033 in patients with metastatic breast cancer.

Secondary Endpoints

Secondary objectives include an assessment of safety and patient reported outcomes (eg, quality of life [QOL])
correlations between erbB expression and efficacy
exploratory analyses of soluble erbB-2 or other biomarkers
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
CI-1033DRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexFEMALE
Healthy VolunteersNo
Study Sites66

Inclusion Criteria: * Female, at least 18 years of age * Histologically confirmed diagnosis of breast cancer * Metastatic (Stage IV) disease * Progressive or recurrent disease following the most recent therapy * No more than 2 different, prior cytotoxic chemotherapy regimens for metastatic disease ...

Countries:United StatesBelgiumCanadaFranceIrelandItalySpainSwedenUnited Kingdom
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Frequently asked questions about CI-1033

What is CI 1033 used for?

CI 1033 is an investigational small molecule being studied for the treatment of lung neoplasms, breast neoplasms, and non-small cell lung carcinoma. It has been evaluated in clinical trials for advanced non-small cell lung cancer, metastatic breast cancer, and as a first-line chemotherapy combination in non-small cell lung cancer patients.

Who makes CI 1033?

CI 1033 is being developed by Pfizer, Inc., which trades under the ticker symbol PFE. The drug is an investigational small molecule in the oncology therapeutic area, and it has been studied in clinical trials for various cancer indications.

What phase is CI 1033 in?

CI 1033 is in Phase 1 clinical development. It has completed three clinical trials, including two Phase 2 studies and one Phase 1 study. The drug is investigational and has not been approved by regulatory authorities.

What clinical trials is CI 1033 in?

CI 1033 has been studied in three completed clinical trials: NCT00050830, a Phase 2 study in advanced non-small cell lung cancer; NCT00051051, a Phase 2 study in metastatic breast cancer; and NCT00174356, a Phase 1 study combining CI 1033 with paclitaxel and carboplatin in non-small cell lung cancer.

Is CI 1033 the same as CI-1033?

Yes, CI 1033 and CI-1033 refer to the same drug. The name appears in clinical trial records with and without a hyphen, but both refer to the investigational small molecule being developed by Pfizer for the treatment of lung and breast cancers.