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ARRY-502

Phase 1

Healthy | Small molecule | Other |Pfizer, Inc.|Last Updated: Oct 5, 2020

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment32

FDA Designations

No designations recorded

Clinical trial landscape

ARRY-502 · 1 trial · 1 indication

Phase 1 1
NCT01349725A Safety Study of ARRY-502 in Healthy SubjectsHealthy
COMPLETED32 Analytics
PHASE1COMPLETED
A Safety Study of ARRY-502 in Healthy Subjects
HealthyUnlock trial analytics

Study Endpoints

Primary Endpoints

Characterize the safety profile of the study drug as determined by adverse events, clinical laboratory tests, electrocardiograms and vital signs.
3 weeks
Characterize the pharmacokinetics of the study drug and metabolite as determined by plasma concentrations.
2 weeks

Secondary Endpoints

Characterize the pharmacodynamics of the study drug as determined by laboratory assays.
2 weeks
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeOTHER

Treatment Arms

ArmTypeDescription
ARRY-502EXPERIMENTAL -
PlaceboPLACEBO_COMPARATOR -

Interventions

NameTypeDescription
ARRY-502DRUGOral; multiple dose, escalating
PlaceboDRUGOral; matching placebo
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Eligibility Criteria

Age Range18 Years to 50 Years
SexALL
Healthy VolunteersYes
Study Sites1

Key Inclusion Criteria: * Healthy male or female between the ages of 18 and 50 years. * Females must be of nonchildbearing potential. * Body mass index (BMI) of 18 to 32 and a total body weight \> 50 kg (110 lbs) and \< 114 kg (250 lbs). * Additional criteria exist. Key Exclusion Criteria: * Evid...

Countries:United States
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Frequently asked questions about ARRY-502

What is ARRY-502 used for?

ARRY-502 is an investigational small molecule being studied for the treatment of persistent asthma. It has also been evaluated in healthy subjects as part of early clinical development. The drug is not approved and remains in clinical trials.

Who makes ARRY-502?

Pfizer, Inc. (NYSE: PFE) is developing ARRY-502. The company has sponsored clinical trials of the drug in healthy subjects and in patients with persistent asthma.

What phase is ARRY-502 in?

ARRY-502 is in clinical development. It has completed a Phase 1 trial in healthy subjects and a Phase 2 trial in patients with persistent asthma. The drug is investigational and not approved for any use.

What clinical trials is ARRY-502 in?

ARRY-502 has been studied in two completed trials: NCT01349725, a Phase 1 safety study in healthy subjects, and NCT01561690, a Phase 2 study in patients with persistent asthma. Both trials were conducted in the United States.

Is ARRY-502 the same as any other drug?

No alternative names for ARRY-502 have been disclosed. The drug is referred to solely by its code name ARRY-502 in clinical trial records and by its developer, Pfizer.