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Pacific Biosciences of California, Inc.

PACBFDA catalysts, PDUFA dates & pipeline intelligence
$1.99
▼ -0.06 · -2.93%

Financials

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Quarterly Cash
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52W LOW $1.0752W HIGH $3.44
Volume
9.19 M
Value Traded
9.03 M
Short % Float
16.56%
-26.84%Week
+47.41%1 Month
+30.07%3 Month
+24.37%6 Month
-95.39%5 Year
-92.61%All Time

Cash Data

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  • Monthly Burn
  • Burn Trend
  • Dilution Risk
  • SEC Filing

Key Stats

Market Cap
618.55 M
EPS (TTM)
-0.42
P/E Ratio
-
Ent. Value
1.03 B
Total Shares
310.72 M
Float Shares
285.14 M
Insiders
8.27%
Institutions
53.89%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
PDUFA
2026
Example Drug
Treatment for example condition requiring FDA review
Phase 3Small MoleculeOncology-
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

PACB Catalyst Timeline

Dated clinical, regulatory and corporate events for Pacific Biosciences of California, Inc.

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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How PACB actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
-Example Drug Phase 3 data readout Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

No drug pipeline

Pacific Biosciences of California, Inc. is a diagnostics company. The clinical trials it takes part in test other companies' drugs, so it has no drug pipeline of its own to score.

Clinical Trial Results

Readouts, endpoints and source filings for every PACB program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
unexplained subfertility and recurrent pregnancy loss2026-05-11participants: 96; couples: 47; individuals: 2; genomic findings: approximately one in 10 couples; likely diagnostic findings: 4.8% of individualsRead MoreHiFi Solves Sub-fertility Consortium in Asia Pacific Reports First Major Study Using HiFi Long-Read Sequencing to Investigate Unexplained Subfertility and Recurrent Pregnancy LossRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Gibson James R IIOfficer (See Remarks)Option 500,000 1,745,663 held$1.18 10/06/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
Casdin Capital, LLC 0.1 % 1.22 M 723.77 K
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

PACB Institutional Ownership Trends

Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-10-16
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Live calls and puts by strike: last price, volume and open interest for every expiry.
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Calls vs Puts by Expiry

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Competitive positioning

How PACB ranks across every disease it competes in

Competitive Position is a premium feature
See how PACB ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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PACB News

PACB
Oct 14, 2026
PACBConferences/Events
▼ -2.9%today

PacBio to Report Third Quarter 2026 Financial Results on November 4, 2026

PacBio has announced that it will hold its quarterly conference call on November 4, 2026, to discuss its third quarter financial results. The call will be accessible via webcast on the company's investor relations website. This event highlights PacBio's commitment to transparency and investor engagement.

Read more →
PACB
Aug 5, 2026
PACBGeneral
▼ -10.4%on this news

PacBio Announces Second Quarter 2026 Financial Results

PacBio reported its second quarter 2026 financial results, revealing a revenue of $39.0 million, driven by consumables and new system placements. The company has initiated a global rollout of its SPRQ-Nx chemistry, enhancing its sequencing capabilities. However, it also faced a net loss of $44.7 million, reflecting increased operational costs and restructuring efforts.

Read more →
PACB
Jul 28, 2026
PACBConferences/Events

PacBio to Participate in the Canaccord Genuity 46th Annual Growth Conference

PacBio will participate in the Canaccord Genuity 46th Annual Growth Conference on August 11, 2026. The event will feature a fireside chat with management, aimed at engaging investors. A live webcast will be available, with a replay accessible for 30 days post-event. PacBio specializes in advanced sequencing solutions for various research applications.

Read more →
PACB
Jul 15, 2026
PACBConferences/Events

PacBio to Report Second Quarter 2026 Financial Results on August 5, 2026

PacBio has announced that it will hold its quarterly conference call to discuss its second quarter 2026 financial results on August 5, 2026. The call is set to take place at 4:30 p.m. Eastern Time and will be accessible via webcast. This event reflects the company's commitment to keeping investors informed about its financial performance.

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PACB
May 22, 2026
PACBConferences/Events

PacBio to Participate in the Jefferies Global Healthcare Conference 2026

PacBio will participate in a fireside chat at the Jefferies Global Healthcare Conference on June 4, 2026. The event will take place in New York and will be accessible via a live webcast. PacBio is known for its high-quality sequencing solutions aimed at resolving complex genetic issues across various research applications.

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PACB
May 21, 2026
PACBConferences/Events
▲ +5%on this newsshared move

PacBio to Participate in the Jefferies Global Healthcare Conference

PacBio will participate in a fireside chat at the Jefferies Global Healthcare Conference on June 4, 2026. The event will take place in New York and will be accessible via a live webcast. This participation highlights PacBio's commitment to sharing advancements in sequencing technology with the healthcare community.

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PACB
May 19, 2026
PACBGeneral

Blank Bio Announces Seed Financing and Strategic Collaboration with PacBio to Advance RNA Foundation Models for Precision Oncology

Blank Bio has announced a $7.2 million seed financing and a strategic collaboration with PacBio to enhance RNA foundation models for precision oncology. The partnership aims to generate high-resolution long-read RNA sequencing data from patient tumor samples, which will improve patient-level predictions and biomarker discovery. The funding will support ongoing model development and collaborations in the oncology field.

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PACB
May 11, 2026
PACBPhases

HiFi Solves Sub-fertility Consortium in Asia Pacific Reports First Major Study Using HiFi Long-Read Sequencing to Investigate Unexplained Subfertility and Recurrent Pregnancy Loss

PacBio announced a significant study from the HiFi Solves Sub-fertility Consortium, utilizing HiFi long-read sequencing to investigate unexplained subfertility and recurrent pregnancy loss. The study involved 96 participants across Asia-Pacific and demonstrated the ability of HiFi sequencing to provide comprehensive genetic insights. Findings suggest that this approach could reduce the need for sequential testing and support informed reproductive counseling.

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PACB
May 7, 2026
PACBGeneral

PacBio Announces First Quarter 2026 Financial Results

PacBio reported its financial results for Q1 2026, highlighting a significant increase in consumable revenue due to the growing adoption of its HiFi technology. The company has expanded its beta program and secured a major collaboration with Basecamp Research for the Trillion Gene Atlas. However, instrument revenue fell short of expectations, impacting overall financial performance.

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PACB
Apr 17, 2026
PACBConferences/Events

PacBio to Report First Quarter 2026 Financial Results on May 7, 2026

PacBio has announced that it will hold a conference call on May 7, 2026, to discuss its financial results for the first quarter of 2026. The call is scheduled for 4:30 p.m. ET and will be accessible via webcast. The company continues to focus on providing advanced sequencing solutions for various research applications.

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PACB
Mar 5, 2026
PACBGeneral

PacBio Announces the Appointment of Chris Gibson to the Board of Directors

PacBio has appointed Dr. Christopher Gibson to its Board of Directors. Dr. Gibson, co-founder of Recursion, brings extensive experience in AI-driven drug discovery and data analytics. His leadership is expected to support PacBio's vision of integrating sequencing technologies with advanced analytics, enhancing their capabilities in biological research and healthcare.

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PACB
Feb 24, 2026
PACBGeneral
▲ +5.1%on this newsshared move

PacBio and DNAstack Launch First Global Federated HiFi Whole Genome Dataset to Accelerate Rare Disease Research

PacBio has partnered with DNAstack to create the first global federated dataset of HiFi whole genome sequencing data. This initiative, part of the HiFi Solves Global Consortium, allows secure international research while keeping sensitive data under institutional control. The collaboration aims to enhance rare disease research by connecting over 10,000 genome sequences from institutions across 15 countries, improving the accuracy of variant detection and accelerating discoveries.

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PACB
Feb 12, 2026
PACBGeneral

PacBio Joins iHope Initiative as First Long-Read Genomic Sequencing Partner

PacBio has partnered with the iHope initiative to integrate its HiFi long-read whole-genome sequencing into iHope's global rare disease genomics program. This collaboration aims to improve diagnostic clarity for patients with rare genetic disorders by providing comprehensive genomic insights. The integration is set to begin in early 2026, enhancing the capabilities of iHope's extensive testing network.

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PACB
Feb 12, 2026
PACBGeneral

PacBio Announces Fourth Quarter and Full Year 2025 Financial Results

PacBio reported its financial results for Q4 and FY 2025, highlighting a revenue increase to $44.6 million in Q4 2025, up from $39.2 million in Q4 2024. Despite this growth, the company faced a significant net loss of $40.4 million in Q4 2025. The annual results also reflected an increase in net loss, totaling $546.4 million for the year, compared to a net loss of $309.9 million in 2024. The company emphasized its growth in consumables and strategic collaborations aimed at advancing genomic testing.

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PACB
Feb 3, 2026
PACBGeneral

PacBio Completes Sale of Short-Read Sequencing Assets

PacBio has completed the sale of its short-read sequencing assets to Illumina for $48.1 million. This strategic move allows PacBio to concentrate on its long-read sequencing technology, which is anticipated to enhance growth opportunities. The transaction closed on January 30, 2026, and includes a non-exclusive license back to PacBio for certain intellectual property.

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PACB
Jan 30, 2026
PACBGeneral

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. UNAUDITED PRO FORMA CONSOLIDATED FINANCIAL STATEMENTS On

Pacific Biosciences of California, Inc. has completed an asset sale to Illumina Cambridge Limited, receiving $50 million in cash and retaining a non-exclusive license for certain intellectual property. The transaction involved the sale of assets related to the company's short-read DNA sequencing technology. Following the asset sale, the company's pro forma financial statements reflect adjustments for the asset's impact on their financial position and operating results as of September 30, 2025. Despite the cash inflow, PacBio continues to experience significant net losses.

Read more →
PACB
Jan 28, 2026
PACBConferences/Events
▼ -7.4%on this news· ran to -20% by day 3shared move

PacBio to Report Fourth Quarter and Full Year 2025 Financial Results on February 12, 2026

PacBio has announced a quarterly conference call to discuss its fourth quarter and full year 2025 financial results, scheduled for February 12, 2026. The call will be accessible via webcast on the company's investor relations website. This event highlights PacBio's commitment to transparency and investor engagement.

Read more →
PACB
Jan 13, 2026
PACBGeneral
▲ +6%on this news· ran to +17% by day 1shared move

PacBio HiFi Adopted as First-Line Sequencing Approach to Investigate Sudden Unexplained Death in Childhood (SUDC)

PacBio has announced that its HiFi whole-genome sequencing will be the primary method used to investigate Sudden Unexplained Death in Childhood (SUDC) in a research project involving 200 families. This approach aims to improve diagnostic yield by accurately detecting complex genetic variants. The initiative is supported by the SUDC Foundation and aims to provide families with clearer answers regarding the genetic factors contributing to SUDC.

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About Pacific Biosciences of California, Inc.

Menlo Park, CA 485 employees pacb.com
Headquarters1305 O'BRIEN DRIVE, MENLO PARK, CA, 94025
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