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Dermagraft, Profore

Phase 3

Venous Leg Ulcer | Unknown | Other |Organogenesis Holdings Inc.|Last Updated: Jun 17, 2018

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment537

FDA Designations

No designations recorded

Clinical trial landscape

Dermagraft, Profore · 1 trial · 1 indication

Phase 3 1
NCT00909870Pivotal Trial of Dermagraft(R) to Treat Venous Leg UlcersVenous Leg Ulcer
COMPLETED537 Analytics
PHASE3COMPLETED
Pivotal Trial of Dermagraft(R) to Treat Venous Leg Ulcers
Venous Leg UlcerUnlock trial analytics

Study Design & Arms

Interventions

NameTypeDescription
Dermagraft(R)DEVICEWeekly application of Dermagraft(R) with Profore compression as a secondary layer, in combination with systematic surgical wound debridement.
ProforeDEVICEWeekly application of Profore compression dressings, in combination with systematic surgical wound debridement.
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Frequently asked questions about Dermagraft, Profore

What is Dermagraft used for?

Dermagraft is an investigational product being studied for the treatment of diabetic foot ulcers and venous leg ulcers. It is developed by Organogenesis Holdings Inc. (ORGO) and is currently in Phase 3 clinical development. Two Phase 3 trials have been completed, one for each indication.

Who makes Dermagraft?

Dermagraft is developed by Organogenesis Holdings Inc., a company traded on the stock exchange under the ticker ORGO. The company is conducting clinical trials to evaluate the product for diabetic foot ulcers and venous leg ulcers.

What phase is Dermagraft in?

Dermagraft is in Phase 3 clinical development. It is not FDA approved and remains investigational. Two Phase 3 trials have been completed, one for venous leg ulcers and two for diabetic foot ulcers, with a total enrollment of 595 patients across all trials.

What clinical trials is Dermagraft in?

Dermagraft has completed three Phase 3 trials. NCT00909870 studied Dermagraft for venous leg ulcers with 537 participants. NCT01181440 and NCT01181453 studied Dermagraft for diabetic foot ulcers, enrolling 281 and 314 participants respectively. All trials are completed.

Is Dermagraft the same as Comparator?

No, Dermagraft and Comparator are not the same. Dermagraft is the investigational product being studied, while Comparator refers to the control group in the clinical trials. The trials are uncontrolled, meaning they do not use a comparator arm.