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ibandronate

Phase 3

Postmenopausal Osteoporosis | Small molecule | Endocrine |Organon & Co.|Last Updated: Feb 2, 2022

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment203

FDA Designations

No designations recorded

Clinical trial landscape

ibandronate · 1 trial · 1 indication

Phase 3 1
NCT00092053Study of Investigational Drug in Osteoporosis (MK-0217-908)Postmenopausal Osteoporosis
COMPLETED203 Analytics
PHASE3COMPLETED
Study of Investigational Drug in Osteoporosis (MK-0217-908)
Postmenopausal OsteoporosisUnlock trial analytics

Study Endpoints

Primary Endpoints

Change in serum levels of CTX-I (log-transformed fraction) from Week 9 to Week 12
Baseline, Week 9, Week 12
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
PlaceboPLACEBO_COMPARATORParticipants will receive 3 placebo tablets once a month, for 3 months, on the first day of each treatment cycle.
ibandronate 100 mgEXPERIMENTALParticipants will receive 2 ibandronate 50 mg tablets and 1 placebo tablet once a month, for 3 months, on the first day of each treatment cycle.
ibandronate 150 mgEXPERIMENTALParticipants will receive 3 ibandronate 50 mg tablets once a month, for 3 months, on the first day of each treatment cycle.

Interventions

NameTypeDescription
PlaceboDRUGtablets
ibandronateDRUG50 mg tablets
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Eligibility Criteria

Age Range50 Years to N/A
SexFEMALE
Healthy VolunteersNo

Inclusion Criteria: -postmenopausal for at least 3 years, with osteoporosis at any of the following sites: \[BMD \> 2.0 standard deviations below young normal mean bone mass for the hip trochanter, PA lumbar spine (L1 to L4), total hip, or femoral neck based on the normative database provided by eac...

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Frequently asked questions about ibandronate

What is ibandronate used for in postmenopausal osteoporosis?

Ibandronate is a small molecule being studied for the treatment of postmenopausal osteoporosis, a condition that weakens bones in women after menopause. It is currently in Phase 3 clinical development as an investigational drug, meaning it has not yet been approved for this use.

Who makes ibandronate?

Ibandronate is being developed by Organon & Co., a pharmaceutical company traded on the New York Stock Exchange under the ticker symbol OGN. The company is conducting clinical trials to evaluate the drug's safety and efficacy for postmenopausal osteoporosis.

What phase is ibandronate in?

Ibandronate is in Phase 3 clinical development. It is an investigational drug, not yet approved by regulatory authorities. One Phase 3 trial has been completed, involving 203 participants with postmenopausal osteoporosis.

What clinical trials is ibandronate in?

Ibandronate has one completed Phase 3 clinical trial registered as NCT00092053, titled "Study of Investigational Drug in Osteoporosis (MK-0217-908)." The trial enrolled 203 women aged 50 years and older with postmenopausal osteoporosis and was placebo-controlled, randomized, and double-blind.

Is ibandronate FDA approved?

Ibandronate is not FDA approved. It is an investigational drug currently in Phase 3 clinical development for postmenopausal osteoporosis. Its safety and efficacy have not been fully established, and it has not received marketing authorization from the FDA or other regulatory bodies.