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Odyssey Therapeutics, Inc.

ODTX
OvervaluedBiotech · Clinical
FDA catalysts, PDUFA dates & pipeline intelligence
$20.73
▲ +0.3 · +1.49%

Financials

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R&D Expenses
Operating CF
Total Assets
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Quarterly Cash
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52W LOW $16.4152W HIGH $18.43
Volume
192.50 K
Value Traded
3.10 M
Short % Float
11.25%
-3.47%Week
-27.94%1 Month
+25.83%3 Month
+26.22%6 Month
+5.68%5 Year
+5.68%All Time

Cash Data

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  • Burn Trend
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  • SEC Filing

Key Stats

Market Cap
996.01 M
EPS (TTM)
-
P/E Ratio
-
Ent. Value
562.94 M
Total Shares
48.03 M
Float Shares
19.64 M
Insiders
59.13%
Institutions
30.35%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 2a data readout
OD-001 (RIPK2)
Ulcerative colitis (moderate-to-severe UC)
Phase 2aSmall MoleculesDigestive System
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

ODTX Catalyst Timeline

Dated clinical, regulatory and corporate events for Odyssey Therapeutics, Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for Odyssey Therapeutics, Inc.

10Total events
3Upcoming
2Tier-1 (high impact)
2026 to 2027Coverage

Upcoming catalysts 2

T2Oral Presentation
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OD-001
T2Trial Initiation
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OD-002

Event history 5

▲Partnership / LicenseCorporate
Evotec and Odyssey enter AI-enabled R&D collaboration in autoimmune and inflammatory diseases
autoimmune and inflammatory diseasessource ↗
●Quarterly UpdateCorporate
Q2 2026 financial results reported
◆Trial InitiationOD-001Trial
Phase 2a combination trial of OD-001 with vedolizumab expected to initiate
ulcerative colitissource ↗
◆IND Enabling CompleteOD-002Preclinical
IND-enabling studies for OD-002 expected to complete
autoimmune diseasessource ↗
◆IND SubmissionOD-002IND
CTA filing for OD-002 expected
autoimmune diseasessource ↗
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How ODTX actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
-Example Drug Phase 3 data readout Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

D39 / 100
Pipeline Score
$208M
Pipeline Value
Overvalued
Valuation Signal
2
Drugs Scored
0.2x
rNPV / MCap
Top 42%
Micro Cap
(rank 276 of 655)
Percentile Rank
Odyssey Therapeutics, Inc. faces pipeline headwinds (39/100), with $519M risk-adjusted pipeline value, led by OD-07656 in Ulcerative Colitis (UC) (Phase 2).
Showing 1 of 2 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
OD-07656 Small moleculeNCT06850727Ulcerative Colitis (UC)Phase 2 RECRUITING 57Nov 1, 2026
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Clinical Trial Results

Readouts, endpoints and source filings for every ODTX program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
OD-001 ulcerative colitisPhase 2a2026-06-17patients completed: 49; clinical remission: 27%; clinical response: 61%Read MoreOdyssey Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate UpdateRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
TPG GP A, LLCFormer 10% OwnerOther 423,111 423,111 held$0.00 05/11/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
Redmile Group, LLC 0.5 % 7.95 M 425.00 K
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Shares held by hedge funds each quarter, and who bought or sold.

ODTX Institutional Ownership Trends

Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
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Put Vol
Put-Call Ratio
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Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

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LastVolOILastVolOI
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Calls vs Puts by Expiry

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Competitive positioning

How ODTX ranks across every disease it competes in

Competitive Position is a premium feature
See how ODTX ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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ODTX News

-ODTX
Sep 16, 2026
ODTXConferences/Events
▲ +5.1%on this news

Odyssey Therapeutics to Participate in Stifel 2026 Virtual Immunology and Inflammation Forum

Odyssey Therapeutics, a clinical-stage biopharmaceutical company, will present at the Stifel 2026 Virtual Immunology and Inflammation Forum on September 23. The event will be accessible via a live webcast and will feature members of the management team discussing the company's innovative approaches to treating autoimmune and inflammatory diseases. Odyssey aims to develop targeted therapies that address unmet medical needs.

Read more →
-ODTX
Aug 26, 2026
ODTXConferences/Events

Odyssey Therapeutics to Participate in Upcoming Investor Conferences

Odyssey Therapeutics, a clinical-stage biopharmaceutical company, announced its participation in several upcoming investor conferences in September 2026. These events include the Cantor Global Healthcare Conference, the Morgan Stanley Global Healthcare Conference, and the H.C. Wainwright Global Investment Conference. The company aims to showcase its innovative approach to treating autoimmune and inflammatory diseases.

Read more →
-ODTX
Aug 6, 2026
ODTXGeneral

Evotec and Odyssey Therapeutics Enter AI-Enabled R&D Collaboration in Autoimmune and Inflammatory Diseases

Evotec SE has partnered with Odyssey Therapeutics to enhance drug discovery for autoimmune and inflammatory diseases. This collaboration will utilize Evotec's AI-enabled platform and advanced screening capabilities to identify new small molecule drug candidates. The goal is to expedite the development of innovative therapies that address significant unmet medical needs.

Read more →
-ODTX
Aug 4, 2026
ODTXPhases
▲ +10.1%on this newsshared move

Odyssey Therapeutics Reports Second Quarter 2026 Financial Results and Provides Corporate Update

Odyssey Therapeutics reported its Q2 2026 financial results, highlighting positive proof-of-concept data for OD-001. The company plans to initiate a Phase 2b monotherapy trial and a Phase 2a combination trial with vedolizumab later this year. With $433.1 million in cash, Odyssey is well-positioned to fund operations into 2028. The company also plans to file a clinical trial application for OD-002 by year-end.

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-ODTX
Jun 17, 2026
ODTXPhases

Odyssey Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate Update

Odyssey Therapeutics reported positive clinical proof-of-concept data for its oral RIPK2 scaffolding inhibitor, OD-001, in a Phase 2a trial for ulcerative colitis. The company has a strong financial position with $464 million expected to support operations through 2028. Odyssey plans to advance OD-001 into late-stage development and initiate additional trials in the near future.

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-ODTX
May 8, 2026
ODTXGeneral

Odyssey Therapeutics Announces Pricing of Upsized Initial Public Offering

Odyssey Therapeutics has announced the pricing of its upsized initial public offering, selling 15.5 million shares at $18.00 each. The offering, which could raise approximately $304 million, includes a concurrent private placement. Trading is expected to begin on the Nasdaq Capital Market under the ticker 'ODTX' on May 8, 2026.

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-ODTX
Mar 10, 2026
ODTXGeneral

Odyssey Therapeutics Appoints H. Martin Seidel, Ph.D., to Scientific Advisory Board

Odyssey Therapeutics has appointed Dr. H. Martin Seidel to its Scientific Advisory Board. Dr. Seidel brings decades of experience in drug discovery and development, having held leadership roles at IFM Therapeutics and Novartis. His expertise is expected to enhance Odyssey's efforts in advancing its clinical programs targeting autoimmune and inflammatory diseases.

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-ODTX
Jan 21, 2026
ODTXGeneral

Odyssey Therapeutics Appoints Jolie M. Siegel as Executive Vice President, General Counsel

Odyssey Therapeutics has appointed Jolie M. Siegel as Executive Vice President and General Counsel. Siegel will oversee legal, compliance, governance, and risk management functions, playing a key role in supporting the company's growth and strategic opportunities. With over two decades of experience in biotechnology and life sciences, her leadership is expected to enhance Odyssey's capabilities in advancing therapies for autoimmune diseases.

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-ODTX
Nov 11, 2025
ODTXGeneral

Odyssey Therapeutics Appoints Dennis Dean, Ph.D., as Executive Vice President, Head of Nonclinical Development

Odyssey Therapeutics has appointed Dennis Dean, Ph.D., as Executive Vice President and Head of Nonclinical Development. Dr. Dean will oversee preclinical research and development, ensuring the progression of drug candidates to clinical trials. His extensive experience in toxicology and pharmacology is expected to enhance the company's capabilities as it advances its portfolio.

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-ODTX
Oct 9, 2025
ODTXGeneral

Odyssey Therapeutics Appoints Pharmaceutical Leader Nia Tatsis, Ph.D., to its Board of Directors

Odyssey Therapeutics has appointed Dr. Nia Tatsis to its Board of Directors. Dr. Tatsis, with over 20 years of experience in regulatory affairs, is expected to contribute significantly to the company's clinical development efforts. Odyssey aims to transform care for autoimmune and inflammatory diseases, and Dr. Tatsis's expertise will support their mission to advance their innovative pipeline.

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-ODTX
Sep 10, 2025
ODTXGeneral

Odyssey Therapeutics Announces Oversubscribed $213 Million Series D Financing to Advance Clinical Pipeline for Autoimmune Diseases

Odyssey Therapeutics has successfully closed a $213 million Series D financing round, with participation from existing and new investors. The funds will support the advancement of their clinical and preclinical programs targeting autoimmune diseases. The company aims to transform patient care through innovative therapies and has appointed new board members to enhance its governance.

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-ODTX
Jan 8, 2025
ODTXGeneral

Odyssey Therapeutics Appoints Jason Haas as Chief Financial Officer

Odyssey Therapeutics has appointed Jason Haas as Chief Financial Officer. With over two decades of experience in financial strategy and operations, Haas will play a key role in advancing the company's financial strategy and growth. His previous roles include CFO at Syros Pharmaceuticals and senior positions in investment banking. The company aims to transform care for autoimmune diseases.

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-ODTX
Oct 28, 2024
ODTXGeneral

Odyssey Therapeutics and Terray Therapeutics Enter Strategic Collaboration to Jointly Discover and Develop First-in-Class Transcription Factor Therapies

Odyssey Therapeutics and Terray Therapeutics have announced a strategic collaboration to discover and develop small molecule therapies targeting transcription factors. This partnership leverages Odyssey's immunology expertise and Terray's advanced AI platform, tNova. The goal is to create innovative treatments for inflammatory diseases, sharing responsibilities and profits equally.

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-ODTX
Oct 27, 2024
ODTXConferences/Events

Odyssey Therapeutics to Present New Data on its Clinical-Stage RIPK2 Scaffolding Inhibitor at the American College of Gastroenterology (ACG) Annual Scientific Meeting 2024

Odyssey Therapeutics will present new data on its RIPK2 scaffolding inhibitor, OD-07656, at the ACG Annual Scientific Meeting 2024. The presentation will highlight the compound's anti-inflammatory effects and its potential to work alongside standard therapies for inflammatory bowel disease. CEO Gary D. Glick emphasized the commitment to developing transformative treatments for patients.

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-ODTX
Oct 2, 2024
ODTXGeneral

Odyssey Therapeutics Appoints Biopharma Veterans Timothy P. Walbert and Ian F. Smith to its Board of Directors

Odyssey Therapeutics has appointed Timothy P. Walbert and Ian F. Smith to its Board of Directors. Both individuals bring extensive experience in the biopharmaceutical industry, with Walbert having led Horizon Therapeutics and Smith having played a key role at Vertex Pharmaceuticals. Their appointments are expected to enhance Odyssey's strategic growth as it advances its pipeline of precision medicines for inflammatory diseases.

Read more →
-ODTX
Sep 27, 2024
ODTXGeneral

Odyssey Therapeutics Announces Formation of Scientific Advisory Board

Odyssey Therapeutics has announced the formation of its Scientific Advisory Board, chaired by Dr. Stephen Blacklow. The board consists of leading experts in immunology and therapeutic development, aimed at guiding the company's innovative approaches to treating inflammatory diseases. Odyssey's mission focuses on advancing precision medicines and improving patient outcomes.

Read more →
-ODTX
Aug 1, 2024
ODTXGeneral

Odyssey Therapeutics Appoints Preeminent Chemist Dr. William Roush as Executive Vice President and Head of Small Molecule Research

Odyssey Therapeutics has appointed Dr. William Roush as Executive Vice President and Head of Small Molecule Research. Dr. Roush brings a wealth of experience in organic and medicinal chemistry, having led numerous drug discovery programs. His role will involve overseeing the preclinical portfolio and accelerating the development of innovative small molecule medicines for autoimmune and inflammatory diseases.

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-ODTX
Apr 4, 2024
ODTXGeneral

Odyssey Therapeutics Announces Strategic Collaboration to Advance AI-Driven Small Molecule Drug Discovery

Odyssey Therapeutics has announced a strategic collaboration with Janssen Pharmaceutica to enhance the discovery and optimization of small molecule medicines. This partnership will leverage artificial intelligence and machine learning to address challenging therapeutic targets. Odyssey will receive upfront payments and potential royalties as they work together on this initiative.

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-ODTX
Dec 4, 2023
ODTXGeneral

Odyssey Therapeutics Announces $101 Million Series C Financing

Odyssey Therapeutics has successfully closed a $101 million Series C financing round, led by Ascenta Capital, with participation from various investors. This funding will facilitate the advancement of multiple clinical programs and support ongoing discovery efforts. The company aims to bring transformative immunology and oncology medicines to patients, with several candidates expected to enter clinical trials within the next year.

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-ODTX
Nov 9, 2023
ODTXConferences/Events

Odyssey Therapeutics to Present Data for Three Immunology Programs at American College of Rheumatology Convergence 2023

Odyssey Therapeutics will present data on three immunology programs at the ACR Convergence 2023. The presentations will include novel therapeutic approaches targeting RIPK2, IRAK4, and TNFR2, which are crucial for treating underserved inflammatory and autoimmune diseases. This marks the first public disclosure of these promising therapies aimed at improving patient outcomes.

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About Odyssey Therapeutics, Inc.

Boston, MA odysseytx.com
Headquarters51 SLEEPER STREET, BOSTON, MA, 02210
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