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OT

Odyssey Therapeutics, Inc.

$24.25

+2.3 (+10.48%)

D 34Pipeline Score Overvalued Biotech · Clinical
Market Cap
1.16 B
EPS
-
P/E Ratio
-
Value Trade
3.10 M
12.37 %
Week
37.94 %
1 Month
42.94 %
3 Month
47.69 %
6 Month
5.68 %
5 Year
5.68 %
All Time
Cash Data
  • Cash Position

    -

  • Monthly Burn

    -

  • Runway

    -

Overview
Volume
226.16 K
52 Week Range
16.41 - 18.43
% held by Insiders
44.12 %
% held by Institutions
30.18 %
Enterprise Value
731.69 M
Total Shares
48.03 M
Short %
11.11 %
Float Shares
27.25 M
Company Description
HQ: 51 SLEEPER STREET, BOSTON, MA,...

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Upcoming Catalyst
Catalyst Drug/Treatment Stage Probability of Approval Description Drug Type Therapeutic Area Source
OD-001 (RIPK2 scaffolding inhibitor) moderate to severe ulcerative colitis
Phase 2a

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Small Molecules
Digestive System
OD-001 (RIPK2 scaffolding inhibitor) moderate to severe ulcerative colitis
Phase 2a

Subscribe to access the data.

Small Molecules
Digestive System
OD-001 (RIPK2 scaffolding inhibitor) moderate to severe ulcerative colitis
Phase 2a

Subscribe to access the data.

Small Molecules
Digestive System
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Catalyst Timeline

Dated clinical, regulatory & corporate events for Odyssey Therapeutics, Inc.

8Total events
3Upcoming
2Tier-1 (high impact)
2026 – 2027Coverage

Upcoming catalysts 2

TBD
T2Oral Presentation
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OD-001
TBD
T2Trial Initiation
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OD-002

Event history 2

TBD
Partnership / LicenseCorporate
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TBD
Quarterly UpdateCorporate
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Past FDA Catalysts & PDUFA Decisions
Date Drug Catalyst Stage Outcome Reaction Event Move % Best Trade %
Example Drug
Phase 3 data readout
Phase 3
0%
0%
Example Drug
Phase 3 data readout
Phase 3
0%
0%
Example Drug
Phase 3 data readout
Phase 3
0%
0%
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Drug Pipeline Intelligence
D34
Pipeline Score
$170M
Pipeline Value
Overvalued
Valuation Signal
2
Drugs Scored
0.2x
rNPV / MCap
Top 47%
Micro Cap
(rank 494 of 931)
Percentile Rank
Odyssey Therapeutics, Inc. faces pipeline headwinds (34/100), with $519M risk-adjusted pipeline value, led by OD-07656 in Ulcerative Colitis (UC) (Phase 2).
Showing 1 of 1 assets
DrugIndicationPhaseNCT IDPTRSrNPVStatusEnrollmentVelocityDesignCompletionML SignalLast Change
OD-07656
Small molecule
Ulcerative Colitis (UC)Phase 2NCT0685072717% $455M RECRUITING 57 STALLED B (63) Nov 1, 2026 -
May 26, 2026
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Clinical Trial Results
Drug Name Indications Phase Date Trial Results Summary Title Source
OD-001
ulcerative colitis
Phase 2a
2026-06-17

patients completed: 49; clinical remission: 27%; clinical response: 61%

Read More

Odyssey Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate Update

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OD-001
ulcerative colitis
Phase 2a
2026-06-17

patients completed: 49; clinical remission: 27%; clinical response: 61%

Read More

Odyssey Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate Update

Read More
OD-001
ulcerative colitis
Phase 2a
2026-06-17

patients completed: 49; clinical remission: 27%; clinical response: 61%

Read More

Odyssey Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate Update

Read More
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Inside Trades
TREND
CORPORATE INSIDERS BOUGHT SHARES WORTH 1.8M IN THE LAST 3 MONTHS
YEARLY INSIDER TRANSACTIONS
Sector Avg.
INSIDERS
SOLD
INSIDERS
BOUGHT
POSITIVE SENTIMENT Based on 22 Insiders Transactions
Unlock Inside Trades data
Hedge Funds
TREND
HEDGE FUNDS INCREASED HOLDINGS BY 200.0K SHARES IN THE LAST QUARTER
Shares Held
2040.00B1530.00B1020.00B510.00B0
Q3
2024
Q4
2024
Q1
2025
Q2
2025
HEDGE FUNDS
SOLD
HEDGE FUNDS
BOUGHT
POSITIVE SENTIMENT Based on 27 hedge funds in the last quarter
18 buying (3 new)·9 selling (1 exited)·2 unchanged
Fund Count
60%
Share Volume
25%
Conviction
15%
HedgeFund Name
( 3 )
% of Portfolio Current MV
-
Shares Owned
-
Activity
Avg Price $0

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K

Example Capital Management

2.5 %
15.00 M
250.00 K
Unlock Hedge Funds table data
ODTX Institutional Ownership Trends
Current Insider %
5.20%
+0.00%
Current Institutional %
62.40%
+0.00%
Total Ownership
67.60%
Insider + Institutional
Data Points
1
1 Ticker(s)
Option Chain Statistics
ExpirationVolumeOpen InterestImplied Volatility CallsImplied Volatility Puts
CallsPutsPut-Call RatioCallsPutsPut-Call RatioIVOiWaIvVWaIvIVOiWaIvVWaIv
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Option Chain
CallsStrikePuts
Last PriceVolumeOpen InterestLast PriceVolumeOpen Interest
No data available
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Open interest
0 600K 1.2M 1.8M Avg OI 1.00 M Open Interest
0 1 2 3 1.1 Put-Call Ratio
Today's Open Interest
1.00 M
Put-Call Ratio
1.1
Put Open Interest
480.00 K
Call Open Interest
520.00 K
Open Interest Avg (30-day)
900,000
Today vs Open Interest Avg (30-day)
11.11%
Option Volume
0 450K 900K 1.4M Avg OV 750.00 K Option Volume
0 1 2 3 0.95 Put-Call Ratio
Today's Volume
750.00 K
Put-Call Ratio
0.95
Put Volume
360.00 K
Call Volume
390.00 K
Volume Avg (30-day)
800,000
Today vs Volume Avg (30-day)
-6.25%
Company News
-ODTX
Aug 6, 2026
ODTXGeneral

Evotec and Odyssey Therapeutics Enter AI-Enabled R&D Collaboration in Autoimmune and Inflammatory Diseases

Evotec SE has partnered with Odyssey Therapeutics to enhance drug discovery for autoimmune and inflammatory diseases. This collaboration will utilize Evotec's AI-enabled platform and advanced screening capabilities to identify new small molecule drug candidates. The goal is to expedite the development of innovative therapies that address significant unmet medical needs.

Read more →
-ODTX
Aug 4, 2026
ODTXPhases
▲ +10.1%on this newsshared move

Odyssey Therapeutics Reports Second Quarter 2026 Financial Results and Provides Corporate Update

Odyssey Therapeutics reported its Q2 2026 financial results, highlighting positive proof-of-concept data for OD-001. The company plans to initiate a Phase 2b monotherapy trial and a Phase 2a combination trial with vedolizumab later this year. With $433.1 million in cash, Odyssey is well-positioned to fund operations into 2028. The company also plans to file a clinical trial application for OD-002 by year-end.

Read more →
-ODTX
Jun 17, 2026
ODTXPhases

Odyssey Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate Update

Odyssey Therapeutics reported positive clinical proof-of-concept data for its oral RIPK2 scaffolding inhibitor, OD-001, in a Phase 2a trial for ulcerative colitis. The company has a strong financial position with $464 million expected to support operations through 2028. Odyssey plans to advance OD-001 into late-stage development and initiate additional trials in the near future.

Read more →
-ODTX
Jan 21, 2026
ODTXGeneral

Odyssey Therapeutics Appoints Jolie M. Siegel as Executive Vice President, General Counsel

Odyssey Therapeutics has appointed Jolie M. Siegel as Executive Vice President and General Counsel. Siegel will oversee legal, compliance, governance, and risk management functions, playing a key role in supporting the company's growth and strategic opportunities. With over two decades of experience in biotechnology and life sciences, her leadership is expected to enhance Odyssey's capabilities in advancing therapies for autoimmune diseases.

Read more →
-ODTX
Nov 11, 2025
ODTXGeneral

Odyssey Therapeutics Appoints Dennis Dean, Ph.D., as Executive Vice President, Head of Nonclinical Development

Odyssey Therapeutics has appointed Dennis Dean, Ph.D., as Executive Vice President and Head of Nonclinical Development. Dr. Dean will oversee preclinical research and development, ensuring the progression of drug candidates to clinical trials. His extensive experience in toxicology and pharmacology is expected to enhance the company's capabilities as it advances its portfolio.

Read more →
-ODTX
Oct 9, 2025
ODTXGeneral

Odyssey Therapeutics Appoints Pharmaceutical Leader Nia Tatsis, Ph.D., to its Board of Directors

Odyssey Therapeutics has appointed Dr. Nia Tatsis to its Board of Directors. Dr. Tatsis, with over 20 years of experience in regulatory affairs, is expected to contribute significantly to the company's clinical development efforts. Odyssey aims to transform care for autoimmune and inflammatory diseases, and Dr. Tatsis's expertise will support their mission to advance their innovative pipeline.

Read more →
-ODTX
Sep 10, 2025
ODTXGeneral

Odyssey Therapeutics Announces Oversubscribed $213 Million Series D Financing to Advance Clinical Pipeline for Autoimmune Diseases

Odyssey Therapeutics has successfully closed a $213 million Series D financing round, with participation from existing and new investors. The funds will support the advancement of their clinical and preclinical programs targeting autoimmune diseases. The company aims to transform patient care through innovative therapies and has appointed new board members to enhance its governance.

Read more →
-ODTX
Jan 8, 2025
ODTXGeneral

Odyssey Therapeutics Appoints Jason Haas as Chief Financial Officer

Odyssey Therapeutics has appointed Jason Haas as Chief Financial Officer. With over two decades of experience in financial strategy and operations, Haas will play a key role in advancing the company's financial strategy and growth. His previous roles include CFO at Syros Pharmaceuticals and senior positions in investment banking. The company aims to transform care for autoimmune diseases.

Read more →
-ODTX
Oct 28, 2024
ODTXGeneral

Odyssey Therapeutics and Terray Therapeutics Enter Strategic Collaboration to Jointly Discover and Develop First-in-Class Transcription Factor Therapies

Odyssey Therapeutics and Terray Therapeutics have announced a strategic collaboration to discover and develop small molecule therapies targeting transcription factors. This partnership leverages Odyssey's immunology expertise and Terray's advanced AI platform, tNova. The goal is to create innovative treatments for inflammatory diseases, sharing responsibilities and profits equally.

Read more →
-ODTX
Oct 27, 2024
ODTXConferences/Events

Odyssey Therapeutics to Present New Data on its Clinical-Stage RIPK2 Scaffolding Inhibitor at the American College of Gastroenterology (ACG) Annual Scientific Meeting 2024

Odyssey Therapeutics will present new data on its RIPK2 scaffolding inhibitor, OD-07656, at the ACG Annual Scientific Meeting 2024. The presentation will highlight the compound's anti-inflammatory effects and its potential to work alongside standard therapies for inflammatory bowel disease. CEO Gary D. Glick emphasized the commitment to developing transformative treatments for patients.

Read more →
-ODTX
Oct 2, 2024
ODTXGeneral

Odyssey Therapeutics Appoints Biopharma Veterans Timothy P. Walbert and Ian F. Smith to its Board of Directors

Odyssey Therapeutics has appointed Timothy P. Walbert and Ian F. Smith to its Board of Directors. Both individuals bring extensive experience in the biopharmaceutical industry, with Walbert having led Horizon Therapeutics and Smith having played a key role at Vertex Pharmaceuticals. Their appointments are expected to enhance Odyssey's strategic growth as it advances its pipeline of precision medicines for inflammatory diseases.

Read more →
-ODTX
Sep 27, 2024
ODTXGeneral

Odyssey Therapeutics Announces Formation of Scientific Advisory Board

Odyssey Therapeutics has announced the formation of its Scientific Advisory Board, chaired by Dr. Stephen Blacklow. The board consists of leading experts in immunology and therapeutic development, aimed at guiding the company's innovative approaches to treating inflammatory diseases. Odyssey's mission focuses on advancing precision medicines and improving patient outcomes.

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-ODTX
Aug 1, 2024
ODTXGeneral

Odyssey Therapeutics Appoints Preeminent Chemist Dr. William Roush as Executive Vice President and Head of Small Molecule Research

Odyssey Therapeutics has appointed Dr. William Roush as Executive Vice President and Head of Small Molecule Research. Dr. Roush brings a wealth of experience in organic and medicinal chemistry, having led numerous drug discovery programs. His role will involve overseeing the preclinical portfolio and accelerating the development of innovative small molecule medicines for autoimmune and inflammatory diseases.

Read more →
-ODTX
Apr 4, 2024
ODTXGeneral

Odyssey Therapeutics Announces Strategic Collaboration to Advance AI-Driven Small Molecule Drug Discovery

Odyssey Therapeutics has announced a strategic collaboration with Janssen Pharmaceutica to enhance the discovery and optimization of small molecule medicines. This partnership will leverage artificial intelligence and machine learning to address challenging therapeutic targets. Odyssey will receive upfront payments and potential royalties as they work together on this initiative.

Read more →
-ODTX
Dec 4, 2023
ODTXGeneral

Odyssey Therapeutics Announces $101 Million Series C Financing

Odyssey Therapeutics has successfully closed a $101 million Series C financing round, led by Ascenta Capital, with participation from various investors. This funding will facilitate the advancement of multiple clinical programs and support ongoing discovery efforts. The company aims to bring transformative immunology and oncology medicines to patients, with several candidates expected to enter clinical trials within the next year.

Read more →
-ODTX
Nov 9, 2023
ODTXConferences/Events

Odyssey Therapeutics to Present Data for Three Immunology Programs at American College of Rheumatology Convergence 2023

Odyssey Therapeutics will present data on three immunology programs at the ACR Convergence 2023. The presentations will include novel therapeutic approaches targeting RIPK2, IRAK4, and TNFR2, which are crucial for treating underserved inflammatory and autoimmune diseases. This marks the first public disclosure of these promising therapies aimed at improving patient outcomes.

Read more →
Competitive Position
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