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Phase 3

Open Angle Glaucoma and Ocular Hypertension | Small molecule | Cardiovascular |Ocular Therapeutix, Inc.|Last Updated: Jun 9, 2023

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment40
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT04061044A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular InsertPHASE3 COMPLETED 40Jul 10, 2018Sep 22, 2020Jun 9, 20231 United States
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Study Endpoints
Primary Endpoints
Incidence of Treatment-Related Adverse Events (Safety and Tolerability)
12 months
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Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
TreatmentEXPERIMENTAL -
Interventions
NameTypeDescription
Ophthalmic InsertDRUGTravoprost, 0.32 mg
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Had prior bilateral treatment and completion, through a minimum of week 12, of the OTX-16-002 trial * Are informed of the nature of the study and subject is able to comply with study requirements and visit schedule for one year * Have provided written informed consent, approve...

Countries:United States
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