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Xylometazoline

Phase 3

Common Cold | Small molecule | Infectious Disease |Novartis AG|Last Updated: May 3, 2007

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment60

FDA Designations

No designations recorded

Clinical trial landscape

Xylometazoline · 1 trial · 1 indication

Phase 3 1
NCT00452270Decongestant Effect, Timing of Effect and Impact on Sleep and General Well-Being of Xylometazoline in Subjects With a Common ColdCommon Cold
COMPLETED60 Analytics
PHASE3COMPLETED
Decongestant Effect, Timing of Effect and Impact on Sleep and General Well-Being of Xylometazoline in Subjects With a Common Cold
Common ColdUnlock trial analytics

Study Endpoints

Primary Endpoints

To evaluate the decongestant effect of xylometazoline in subjects with
common cold compared to placebo treatment by means of rhinomanometry over a period of 12 hours.

Secondary Endpoints

To measure the peak subjective effect, time to onset of subjective relief of nasal obstruction
and duration of relief of nasal obstruction
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
XylometazolineDRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Over 18 years * Have had moderate common cold symptoms for less than 36 hours. Exclusion Criteria: * Congested/runny nose for more than two continuous weeks in the previous 12 months * Deviated septum or nasal polyps * Recent use of antibiotics * Recent sinusitis Other prot...

Countries:United Kingdom
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Frequently asked questions about Xylometazoline

What is Xylometazoline used for?

Xylometazoline is used for the relief of nasal congestion associated with the common cold. It is a small molecule being developed by Novartis AG for this indication, and it is currently in Phase 3 clinical development.

How does Xylometazoline work?

Xylometazoline is a decongestant that works by constricting blood vessels in the nasal passages, which reduces swelling and congestion. It is being studied for its decongestant effect in patients with the common cold.

Who makes Xylometazoline?

Xylometazoline is being developed by Novartis AG, a pharmaceutical company listed on the stock exchange under the ticker NVS. The drug is currently in Phase 3 clinical trials for the treatment of common cold symptoms.

What phase is Xylometazoline in?

Xylometazoline is in Phase 3 clinical development. It is an investigational drug and has not yet been approved by regulatory authorities. The ongoing Phase 3 trial is studying its decongestant effects in patients with the common cold.

What clinical trials is Xylometazoline in?

Xylometazoline has one completed Phase 3 clinical trial, identified as NCT00452270. This trial, titled 'Decongestant Effect, Timing of Effect and Impact on Sleep and General Well-Being of Xylometazoline in Subjects With a Common Cold,' enrolled 60 participants in the United Kingdom.

Is Xylometazoline the same as other decongestants?

Xylometazoline is a specific decongestant compound. It is being studied for its effects on nasal congestion in the common cold, and its clinical trial focuses on the timing of its decongestant effect and its impact on sleep and general well-being.