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Vatalinib

Phase 1

Healthy | Small molecule | Other |Novartis AG|Last Updated: Nov 19, 2009

Success Probability

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Market & Valuation

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Trial Design

RandomizedUNCONTROLLED
Total Trials1
Total Enrollment24

FDA Designations

No designations recorded

Clinical trial landscape

Vatalinib · 1 trial · 1 indication

Phase 1 1
NCT00426452A Drug-drug Interaction Study of Oral 1250 mg of Vatalinib Administered Under Fasting and Fed Conditions With a Proton-pump Inhibitor in Healthy Sterile or Postmenopausal Female VolunteersHealthy
COMPLETED24 Analytics
PHASE1COMPLETED
A Drug-drug Interaction Study of Oral 1250 mg of Vatalinib Administered Under Fasting and Fed Conditions With a Proton-pump Inhibitor in Healthy Sterile or Postmenopausal Female Volunteers
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Study Endpoints

Primary Endpoints

Assess the effect of multiple doses of a proton-pump inhibitor on the pharmacokinetics of a single dose of Vatalinib under fasting and fed conditions.

Secondary Endpoints

Safety of a single dose of Vatalinib before and after a proton-pump inhibitor under fasting and fed conditions as assessed by adverse events, laboratory values, electrocardiograms, and vital signs.
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeTREATMENT

Interventions

NameTypeDescription
VatalinibDRUG -
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Eligibility Criteria

Age Range35 Years to 70 Years
SexFEMALE
Healthy VolunteersNo

Inclusion criteria * Healthy female * Surgically sterile or post-menopausal * At least a weight of 50 kg and have a body mass index (BMI) ≤33.0 * Non-smokers or those who smoke 25 cigarettes or less per day Exclusion criteria * Use of certain prescription and over the counter drugs * Having receive...

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Frequently asked questions about Vatalinib

What is Vatalinib used for?

Vatalinib is an investigational small molecule being studied in healthy volunteers. It is not approved for any disease and is currently in Phase 1 clinical development. The only completed trial evaluated its use in healthy sterile or postmenopausal female volunteers, focusing on drug-drug interactions.

Who makes Vatalinib?

Vatalinib is being developed by Novartis AG, a multinational pharmaceutical company traded on the New York Stock Exchange under the ticker symbol NVS. The company is conducting clinical research to evaluate the drug's properties in early-stage trials.

What phase is Vatalinib in?

Vatalinib is in Phase 1 clinical development. It is an investigational drug, meaning it has not been approved by regulatory authorities. The single trial listed is a completed Phase 1 study, and the drug remains under investigation for potential future use.

What clinical trials is Vatalinib in?

Vatalinib has one completed clinical trial registered under NCT00426452. This Phase 1 study evaluated a 1250 mg oral dose of Vatalinib under fasting and fed conditions with a proton-pump inhibitor in healthy female volunteers. The trial enrolled 24 participants and was not blinded or controlled.

Is Vatalinib FDA approved?

No, Vatalinib is not FDA approved. It is an investigational drug currently in Phase 1 clinical trials. The available data shows only one completed study in healthy volunteers, and the drug has not progressed to later-stage trials or regulatory submission.