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SOM230 s.c

Phase 2

Cushing's Syndrome | Small molecule | Endocrine |Novartis AG|Last Updated: Nov 7, 2016

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment26

FDA Designations

No designations recorded

Clinical trial landscape

SOM230 s.c · 1 trial · 1 indication

Phase 2 1
NCT00088608A Study to Assess SOM230 in Patients With Pituitary Cushing's DiseaseCushing's Syndrome
COMPLETED26 Analytics
PHASE2COMPLETED
A Study to Assess SOM230 in Patients With Pituitary Cushing's Disease
Cushing's SyndromeUnlock trial analytics

Study Endpoints

Primary Endpoints

Urinary Free Cortisol after 15 days of treatment

Secondary Endpoints

Serum cortisol
ACTH
Clinical manifestations
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
SOM230 s.c.DRUG -
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Eligibility Criteria

Age Range18 Years to 80 Years
SexALL
Healthy VolunteersNo
Study Sites5

Inclusion Criteria: * Patients with pituitary Cushing's disease within the two months prior to study entry * Patients for whom written informed consent to participate in the study has been obtained * Female patients of child bearing potential who have not undergone clinically documented total hyste...

Countries:United States
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Frequently asked questions about SOM230 s.c

What is SOM230 s.c used for?

SOM230 s.c is an investigational small molecule being studied for the treatment of Cushing's Syndrome, a condition caused by excess cortisol. It is administered subcutaneously and is currently in clinical development, having completed a Phase 2 trial.

What does SOM230 s.c target?

SOM230 s.c is a somatostatin analog that targets somatostatin receptors. By binding to these receptors, it is designed to inhibit the secretion of adrenocorticotropic hormone (ACTH), which can help reduce cortisol levels in patients with Cushing's Syndrome.

Who makes SOM230 s.c?

SOM230 s.c is being developed by Novartis AG, a multinational pharmaceutical company listed on the stock exchange under the ticker symbol NVS. The drug is in Phase 2 clinical development for the treatment of Cushing's Syndrome.

What phase is SOM230 s.c in?

SOM230 s.c is in Phase 2 clinical development. It has completed one Phase 2 trial, which was an uncontrolled study involving 26 patients with Cushing's Syndrome. The drug is not yet approved and remains investigational.

What clinical trials is SOM230 s.c in?

SOM230 s.c has been studied in one clinical trial with the identifier NCT00088608. This Phase 2 trial, titled 'A Study to Assess SOM230 in Patients With Pituitary Cushing's Disease,' was completed in the United States and enrolled 26 adult patients with Cushing's Syndrome.

Is SOM230 s.c the same as pasireotide?

SOM230 s.c is also known as pasireotide, a somatostatin analog. It is being developed by Novartis AG for the treatment of Cushing's Syndrome and has completed a Phase 2 clinical trial under the identifier NCT00088608.