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QCC374

Phase 1

Healthy Subjects | Small molecule | Other |Novartis AG|Last Updated: Mar 22, 2016

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment66

FDA Designations

No designations recorded

Clinical trial landscape

QCC374 · 1 trial · 1 indication

Phase 1 1
NCT02245828A First in Human Study to Assess the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of QCC374Healthy Subjects
COMPLETED66 Analytics
PHASE1COMPLETED
A First in Human Study to Assess the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of QCC374
Healthy SubjectsUnlock trial analytics

Study Endpoints

Primary Endpoints

Safety and tolerability
39 days

Number of Participants with Adverse Events

Secondary Endpoints

AUCinf
39 days
AUClast
39 days
AUCtau
39 days
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Study Design & Arms

AllocationRANDOMIZED
MaskingTRIPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
PlaceboPLACEBO_COMPARATORPlacebo comparator
QCC374EXPERIMENTALSingle and multiple ascending doses of QCC374

Interventions

NameTypeDescription
QCC374DRUGSingle and multiple ascending doses of QCC374
PlaceboDRUGPlacebo comparator
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Eligibility Criteria

Age Range18 Years to 55 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. Written informed consent must be obtained before any assessment is performed. 2. Healthy male and female subjects age 18 to 55 years of age included, and in good health as determined by past medical history, physical examination, vital signs, electrocardiogram, and laboratory...

Countries:United Kingdom
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Frequently asked questions about QCC374

What is QCC374?

QCC374 is an investigational small molecule being developed by Novartis AG. It is currently in Phase 1 clinical development. The drug has been studied in healthy subjects, with one completed trial assessing its safety, tolerability, and pharmacokinetics.

What is QCC374 used for?

QCC374 is being studied for use in healthy subjects. It is an investigational drug in early clinical development, and its intended therapeutic use has not been established. The completed Phase 1 trial focused on safety, tolerability, and pharmacokinetics.

Who makes QCC374?

QCC374 is being developed by Novartis AG, a multinational pharmaceutical company listed on the stock exchange under the ticker NVS. The company conducted a Phase 1 clinical trial to evaluate the drug's safety and tolerability in healthy volunteers.

What phase is QCC374 in?

QCC374 is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. One Phase 1 trial has been completed, and the drug is no longer in active clinical trials according to available data.

What clinical trials is QCC374 in?

QCC374 was studied in a single Phase 1 clinical trial with the identifier NCT02245828. This was a first-in-human study to assess the safety, tolerability, and pharmacokinetics of single and multiple ascending doses of QCC374. The trial enrolled 66 healthy subjects in the United Kingdom and has been completed.

Is QCC374 the same as any other drug?

QCC374 is the only name provided for this investigational drug. No alternative names have been identified in the available information. It is a small molecule being developed by Novartis AG.