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Nadolol

Phase 1

High Blood Pressure | Small molecule | Neurology |Novartis AG|Last Updated: Mar 28, 2017

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLED
Total Trials1
Total Enrollment34

FDA Designations

No designations recorded

Clinical trial landscape

Nadolol · 1 trial · 3 indications

Phase 1 1
NCT00960245Relative Bioavailability Study of Nadolol (1 x 80 mg) Tablets Under Fasting ConditionsHigh Blood Pressure
COMPLETED34 Analytics
PHASE1COMPLETED
Relative Bioavailability Study of Nadolol (1 x 80 mg) Tablets Under Fasting Conditions
High Blood PressureUnlock trial analytics

Study Endpoints

Primary Endpoints

Bioequivalence based on AUC and Cmax
21 days
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1EXPERIMENTALNadolol (1 x 80 mg) Tablets (Invamed, Inc)
2ACTIVE_COMPARATORCorgard (1 x 80 mg) Tablets (Bristol Laboratories)

Interventions

NameTypeDescription
Nadolol (1 x 80 mg) Tablets (Invamed, Inc)DRUG -
Corgard (1 x 80 mg) Tablets (Bristol Laboratories)DRUG -
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Eligibility Criteria

Age Range18 Years to 40 Years
SexMALE
Healthy VolunteersYes

Inclusion Criteria: * No clinically significant abnormal finding on physical exam, medical history, or clinical laboratory results on screening. Exclusion Criteria: * Positive test results for HIV or hepatitis B or C. * Treatment for drug or alcohol dependence.

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Frequently asked questions about Nadolol

What is Nadolol used for?

Nadolol is a small molecule being studied for the treatment of high blood pressure. It is also being investigated for use in migraine headaches and chest pain. The drug is currently in Phase 1 clinical development and is being developed by Novartis AG.

Who makes Nadolol?

Nadolol is being developed by Novartis AG, a pharmaceutical company traded on the New York Stock Exchange under the ticker symbol NVS. The drug is currently in Phase 1 clinical development for the treatment of high blood pressure.

What phase is Nadolol in?

Nadolol is in Phase 1 clinical development. It is an investigational drug being studied for high blood pressure, and it has not been approved by the FDA. The drug is still in the early stages of clinical testing.

What clinical trials is Nadolol in?

Nadolol has one completed clinical trial registered under the identifier NCT00960245. This Phase 1 study evaluated the relative bioavailability of Nadolol 80 mg tablets under fasting conditions in 34 healthy male volunteers.

Is Nadolol FDA approved?

Nadolol is not FDA approved. It is an investigational drug currently in Phase 1 clinical development for the treatment of high blood pressure. The drug is being studied in clinical trials but has not yet received regulatory approval.