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N-acetylcysteine

Phase 2

Common Cold Associated With Cough | Small molecule | Infectious Disease |Novartis AG|Last Updated: Jul 11, 2016

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment70

FDA Designations

No designations recorded

Clinical trial landscape

N-acetylcysteine · 1 trial · 1 indication

Phase 2 1
NCT02379637Study to Evaluate the Efficacy of N-acetylcysteine (NAC) in the Treatment of the Common Cold and CoughCommon Cold Associated With Cough
COMPLETED70 Analytics
PHASE2COMPLETED
Study to Evaluate the Efficacy of N-acetylcysteine (NAC) in the Treatment of the Common Cold and Cough
Common Cold Associated With CoughUnlock trial analytics

Study Endpoints

Primary Endpoints

Cough Count (Number of Coughs Will be Measured by a 24-hour Ambulatory Cough Monitoring System for the First 72 Hours)
72 hours

Number of coughs will be measured by a 24-hour ambulatory cough monitoring system for the first 72 hours

Secondary Endpoints

Safety of Daily Dose of NAC (Number of Patients With Adverse Advents)
7 Days
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
A N-acetylcysteineEXPERIMENTALN-acetylcysteine
B PlaceboPLACEBO_COMPARATORPlacebo

Interventions

NameTypeDescription
N-acetylcysteineDRUG -
PlaceboDRUG -
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites5

Inclusion Criteria: * Cold/URTI symptoms occurring no more than 4 days * cough due to a cold or acute viral (URTI) with an onset of no more than 3 days * cough frequency with specified cut-off Exclusion Criteria: * A subchronic, or chronic cough (cough duration \> 2 months) due to any condition o...

Countries:Canada
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Frequently asked questions about N-acetylcysteine

What is N-acetylcysteine used for?

N-acetylcysteine is being studied for the treatment of the common cold associated with cough. It is a small molecule being developed by Novartis AG. The drug is currently in Phase 2 clinical development for this indication.

What does N-acetylcysteine target?

N-acetylcysteine is a small molecule. Its specific molecular target has not been disclosed in the available information. The drug is being investigated for its potential to treat the common cold associated with cough.

Who makes N-acetylcysteine?

N-acetylcysteine is being developed by Novartis AG, a pharmaceutical company listed on the stock exchange under the ticker symbol NVS. The company is conducting clinical trials to evaluate the drug's efficacy in treating the common cold associated with cough.

What phase is N-acetylcysteine in?

N-acetylcysteine is in Phase 2 clinical development. It is an investigational drug and has not been approved by regulatory authorities. The drug is being studied for the treatment of the common cold associated with cough.

What clinical trials is N-acetylcysteine in?

N-acetylcysteine has one completed Phase 2 clinical trial with the identifier NCT02379637. This trial evaluated the efficacy of N-acetylcysteine in the treatment of the common cold and cough. The study enrolled 70 participants in Canada and was randomized, double-blind, and placebo-controlled.

Is N-acetylcysteine the same as NAC?

N-acetylcysteine is commonly referred to as NAC. The clinical trial NCT02379637 uses the abbreviation NAC to refer to the drug. Both names refer to the same investigational compound being developed for the common cold associated with cough.