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Mometasone furoate

Phase 1

Healthy | Small molecule | Other |Novartis AG|Last Updated: Jun 22, 2007

Success Probability

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Market & Valuation

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Trial Design

RandomizedUNCONTROLLED
Total Trials1
Total Enrollment24

FDA Designations

No designations recorded

Clinical trial landscape

Mometasone furoate · 1 trial · 1 indication

Phase 1 1
NCT00418509Study of Mometasone Furoate/Formoterol Fumarate Inhalation Combination in Healthy VolunteersHealthy
COMPLETED24 Analytics
PHASE1COMPLETED
Study of Mometasone Furoate/Formoterol Fumarate Inhalation Combination in Healthy Volunteers
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Study Endpoints

Primary Endpoints

Dosage form and dose proportionality of mometasone and formoterol from combination metered dose inhalers (MDI).

Secondary Endpoints

Extrapulmonary (systemic) effects and safety of mometasone and formoterol from combination MDI formulations.
Plasma and urine concentrations mometasone and formoterol
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeTREATMENT

Interventions

NameTypeDescription
Mometasone furoateDRUG -
Formoterol fumarateDRUG -
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Healthy, male or female subjects age 18 to 65 years of age (included) * In good health as confirmed by past medical history * Female subjects must be either surgically sterilized at least 6 months prior to study participation or post-menopausal (no regular menstrual bleeding f...

Countries:United Kingdom
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Frequently asked questions about Mometasone furoate

What is Mometasone furoate used for?

Mometasone furoate is an investigational small molecule being studied for use in asthma and in healthy volunteers. It is being developed by Novartis AG (NVS). Clinical trials have evaluated it in patients with persistent asthma, including children, adolescents, and adults, as well as in healthy adult volunteers.

What does Mometasone furoate target?

Mometasone furoate is a corticosteroid that works by reducing inflammation in the airways. It is being studied in combination with other inhaled medications, such as formoterol fumarate and indacaterol, for the treatment of asthma. The drug is delivered via inhalation devices.

Who makes Mometasone furoate?

Mometasone furoate is being developed by Novartis AG, a global healthcare company traded under the ticker NVS. Novartis has sponsored multiple clinical trials investigating the drug for asthma and in healthy volunteers.

What phase is Mometasone furoate in?

Mometasone furoate is in clinical development, with trials listed as Phase 1 and Phase 2. It is not approved and remains investigational. Three trials have been completed, and no active trials are currently listed.

What clinical trials is Mometasone furoate in?

Mometasone furoate has been studied in three completed trials: NCT00418509 in healthy volunteers, NCT00746330 in children with persistent asthma, NCT01555151 in adults and adolescents with asthma, and NCT04589663 in children with asthma. These trials evaluated safety, efficacy, and pharmacokinetics.

Is Mometasone furoate the same as formoterol or indacaterol?

No, Mometasone furoate is a separate drug, a corticosteroid. It has been studied in combination with formoterol fumarate and with indacaterol, which are bronchodilators. The trials listed evaluate the combination products, not Mometasone furoate alone.