Recent Updates
Recently added Catalysts

FTY720

Phase 3

Relapsing Multiple Sclerosis | Small molecule | Immunology |Novartis AG|Last Updated: Feb 23, 2017

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment2,417
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT01127750Tolerability and Safety and Health Outcomes in Relapsing Multiple Sclerosis (MS) PatientsPHASE3 COMPLETED 2,417May 1, 2010Oct 1, 2011Feb 23, 2017289 Australia, Austria +21
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Evaluate the safety and tolerability profile of FTY720 in patients with relapsing forms of MS
4 months
Secondary Endpoints
Incidence of macular edema
4 months
Incidence of bradyarrhythmic electrocardiograms (ECGs)
4 months
Patient reported outcomes indices in multiple sclerosis (PRIMUS), short form health survey-12, and treatment satisfaction questionnaire for medication (TSQM-9)
4 months
Unlock Study Endpoints
Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
FTY720EXPERIMENTAL -
Interventions
NameTypeDescription
FTY720DRUG -
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — 65 Years
SexALL
Healthy VolunteersNo
Study Sites289

Inclusion Criteria: * 18-65 years of age, must have relapsing MS Exclusion Criteria: * Patients with a type of MS that is not relapsing * Patients with history of chronic immune disease * Patients with a history of certain cancers * Diabetic patients with certain eye disorders * Patients who are ...

Countries:AustraliaAustriaBelgiumCanadaCzechiaDenmarkFinlandGermanyGreeceHungaryIrelandItalyNetherlandsNorwayPolandPortugalRussiaSlovakiaSpainSwedenSwitzerlandTurkey (Türkiye)United Kingdom
Unlock Eligibility Criteria