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Everolmus

Phase 1

Non-Hodgkin's Lymphoma | Small molecule | Oncology |Novartis AG|Last Updated: Dec 21, 2020

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment13

FDA Designations

No designations recorded

Clinical trial landscape

Everolmus · 1 trial · 1 indication

Phase 1 1
NCT00622258A Phase I Dose Escalation Study of RAD001 Administered in Patients With Relapsed or Refractory Non-Hodgkin's LymphomaNon-Hodgkin's Lymphoma
COMPLETED13 Analytics
PHASE1COMPLETED
A Phase I Dose Escalation Study of RAD001 Administered in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Non-Hodgkin's LymphomaUnlock trial analytics

Study Endpoints

Primary Endpoints

To assess the safety and tolerability of RAD001 in Japanese patients with relapsed or refractory non-Hodgkin's lymphoma
whole study period
To assess the pharmacokinetics in Japanese patients
1st sycle

Secondary Endpoints

To seek preliminary evidence of efficacy in this population
Every 2 cycles
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
EverolimusEXPERIMENTAL -

Interventions

NameTypeDescription
EverolmusDRUG -
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Eligibility Criteria

Age Range20 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites8

Inclusion criteria: * Patients must have histopathologically confirmed diagnosis of non-Hodgkin's lymphoma * Patients must have disease that is either relapsed or refractory after at least one prior treatment regimen and must not be eligible for any standard treatments * Patients must not have rece...

Countries:Japan
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Frequently asked questions about Everolmus

What is Everolmus used for in Non-Hodgkin's Lymphoma?

Everolmus is an investigational small molecule being studied for the treatment of relapsed or refractory Non-Hodgkin's Lymphoma. It is being developed by Novartis AG and is currently in Phase 1 clinical development. The drug has been evaluated in a completed Phase 1 dose escalation study in patients with this condition.

Who makes Everolmus?

Everolmus is being developed by Novartis AG, a pharmaceutical company traded on the stock exchange under the ticker symbol NVS. The drug is currently in Phase 1 clinical development for the treatment of Non-Hodgkin's Lymphoma, a type of cancer affecting the lymphatic system.

What phase is Everolmus in?

Everolmus is in Phase 1 clinical development. It has completed a Phase 1 dose escalation study in patients with relapsed or refractory Non-Hodgkin's Lymphoma. The drug is investigational and has not yet been approved by regulatory authorities for any use.

What clinical trials is Everolmus in?

Everolmus has been studied in one clinical trial with the identifier NCT00622258, titled "A Phase I Dose Escalation Study of RAD001 Administered in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma." This trial was completed and enrolled 13 participants in Japan, with a minimum age of 20 years.

Is Everolmus the same as RAD001?

Yes, Everolmus is also known as RAD001. The clinical trial NCT00622258, which studied Everolmus in Non-Hodgkin's Lymphoma, refers to the drug as RAD001. This alternative name is used in the context of the Phase 1 dose escalation study conducted in Japan.