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EPO906 epothilone B

Phase 2

Carcinoid | Small molecule | Oncology |Novartis AG|Last Updated: Mar 1, 2017

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment33

FDA Designations

No designations recorded

Clinical trial landscape

EPO906 epothilone B · 1 trial · 2 indications

Phase 2 1
NCT00050349EPO906 in Carcinoid and Other Neuroendocrine TumorsCarcinoid
COMPLETED33 Analytics
PHASE2COMPLETED
EPO906 in Carcinoid and Other Neuroendocrine Tumors
CarcinoidUnlock trial analytics

Study Endpoints

Primary Endpoints

Tumor response as assessed by radiologic techniques and/or physical examination based on Response Evaluation Criteria in Solid Tumors (RECIST)
every 12 weeks

Secondary Endpoints

Time to progression
until documented disease progression, death or date of follow up
Overall survival
after treatment, every 3 months (maximum of 12 months)
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
EPO906EXPERIMENTAL -

Interventions

NameTypeDescription
EPO906 epothilone BDRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites5

Inclusion Criteria: * Patients with biopsy-proven metastatic carcinoid tumors or other neuroendocrine tumors (Islet cell, Gastrinomas and VIPomas) with at least one measurable lesion (other than bone) that has either not been previously irradiated or if previously irradiated has demonstrated progre...

Countries:United States
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Frequently asked questions about EPO906 epothilone B

What is EPO906 epothilone B used for?

EPO906 epothilone B is an investigational small molecule being studied for the treatment of carcinoid and other neuroendocrine tumors. It is in Phase 2 clinical development and has not been approved by regulatory authorities.

What does EPO906 epothilone B target?

EPO906 epothilone B is an epothilone, a class of microtubule-stabilizing agents. It works by binding to tubulin and stabilizing microtubules, which disrupts cell division and can lead to cancer cell death.

Who makes EPO906 epothilone B?

EPO906 epothilone B is being developed by Novartis AG, a multinational pharmaceutical company listed on the New York Stock Exchange under the ticker symbol NVS.

What phase is EPO906 epothilone B in?

EPO906 epothilone B is in Phase 2 clinical development. It is an investigational drug and has not been approved by the FDA or any other regulatory agency.

What clinical trials is EPO906 epothilone B in?

EPO906 epothilone B has been studied in one completed Phase 2 clinical trial, NCT00050349, titled 'EPO906 in Carcinoid and Other Neuroendocrine Tumors.' This trial enrolled 33 participants in the United States and was not randomized or blinded.