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Divalproex

Phase 1

Seizures | Small molecule | Neurology |Novartis AG|Last Updated: Mar 29, 2017

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLED
Total Trials1
Total Enrollment28

FDA Designations

No designations recorded

Clinical trial landscape

Divalproex · 1 trial · 1 indication

Phase 1 1
NCT00864006Bioequivalence Study of Divalproex Sodium 125 MG Delayed Release Tablets Under Fasting ConditionsSeizures
COMPLETED28 Analytics
PHASE1COMPLETED
Bioequivalence Study of Divalproex Sodium 125 MG Delayed Release Tablets Under Fasting Conditions
SeizuresUnlock trial analytics

Study Endpoints

Primary Endpoints

Bioequivalence according to US FDA Guidelines
9 Days
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1EXPERIMENTALDivalproex Sodium 125 MG Delayed Release Tablets Sandoz
2ACTIVE_COMPARATORDepakote 125 MG DR Tablets Abbott Laboratories USA

Interventions

NameTypeDescription
Divalproex SodiumDRUG -
Depakote DR TabletsDRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexMALE
Healthy VolunteersYes

Inclusion Criteria: * No clinically significant findings on physical examination, medical history or laboratory tests on screening Exclusion Criteria: * Positive test for HIV or Hepatitis B and C * History of sensitivity to valproic acid or related compounds

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Frequently asked questions about Divalproex

What is Divalproex used for?

Divalproex is a small molecule being developed by Novartis AG for the treatment of seizures. It is currently in Phase 1 clinical development as an investigational drug. The drug is being studied for its potential to manage seizure disorders, though it has not yet been approved for this use.

Who makes Divalproex?

Divalproex is being developed by Novartis AG, a multinational pharmaceutical company traded on the New York Stock Exchange under the ticker symbol NVS. The company is conducting clinical trials to evaluate the drug's safety and efficacy in treating seizures.

What phase is Divalproex in?

Divalproex is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. The Phase 1 trial has been completed, and the drug is still in the early stages of clinical testing for the treatment of seizures.

What clinical trials is Divalproex in?

Divalproex has one completed clinical trial, NCT00864006, which was a Phase 1 bioequivalence study of Divalproex Sodium 125 MG delayed release tablets under fasting conditions. The trial enrolled 28 healthy male volunteers aged 18 years and older and was active-controlled.

Is Divalproex the same as divalproex sodium?

Divalproex is the drug name, and the clinical trial studied Divalproex Sodium 125 MG delayed release tablets. The trial was designed to assess the bioequivalence of this formulation, indicating that Divalproex and divalproex sodium refer to the same active pharmaceutical ingredient.