Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
Also known as Diclofenac diethylamine 2.32% gel, diclofenac diethylamine gel 2.32%
Diclofenac diethylamine 2.32% · 2 trials · 2 indications
Visual analog scale (0 to 100 mm) A greater change from baseline equates to a better outcome.
Pain on movement: visual analogue scale (VAS) with anchors at 0 mm (no pain) and 100 mm (extreme pain)
| Arm | Type | Description |
|---|---|---|
| diclofenac diethylamine gel 2.32% gel twice a day | EXPERIMENTAL | drug |
| diclofenac diethylamine gel 2.32% gel three times a day | EXPERIMENTAL | drug |
| placebo | PLACEBO_COMPARATOR | placebo |
| 1 | ACTIVE_COMPARATOR | - |
| 2 | PLACEBO_COMPARATOR | - |
| 3 | ACTIVE_COMPARATOR | - |
| Name | Type | Description |
|---|---|---|
| diclofenac diethylamine gel 2.32% | DRUG | diclofenac diethylamine gel 2.32% twice a day |
| Placebo | DRUG | Placebo |
| Diclofenac diethylamine 2.32% gel | DRUG | Diclofenac diethylamine 2.32% gel twice daily |
| Diclofenac diethylamine 2.32% gel / Placebo | DRUG | Diclofenac diethylamine 2.32% gel once daily / Vehicle once daily |
Inclusion Criteria: 1\. Acute sprain of the lateral ankle, Grade I-II . Exclusion Criteria: 1. Any concurrent injury affecting the lower extremities that is painful at rest or on movement, or could affect the mobilization of the patient. 2. Topical analgesic or anti-inflammatory treatment over th...