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Cefdinir

Phase 1

Healthy | Small molecule | Other |Novartis AG|Last Updated: Mar 29, 2017

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedACTIVE_CONTROLLED
Total Trials3
Total Enrollment96
FDA Designations
No designations recorded
Clinical Trials (3)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00882154To Demonstrate the Relative Bioequivalence of Cefdinir and Omnicel 300 mg Capsule Fed ConditionsPHASE1 COMPLETED 28Apr 1, 2005Apr 1, 2005Mar 29, 2017 -
NCT00882700To Demonstrate the Relative Bioequivalence of Cefdinir and Omnicef 300 mg Capsule Fasting ConditionsPHASE1 COMPLETED 28Apr 1, 2005Apr 1, 2005Mar 29, 2017 -
NCT00883883To Demonstrate the Relative Bioequivalence of Cefdinir and Omnicel 250 mg/5 ml Oral Suspension Fed ConditionsPHASE1 COMPLETED 40Apr 1, 2005May 1, 2005Mar 29, 2017 -
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Study Endpoints
Primary Endpoints
Bioequivalence based on AUC and Cmax
7 days
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Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
1EXPERIMENTALCefdinir 300 mg Capsule (Sandoz, Austria)
2ACTIVE_COMPARATOROmnicef Cefdinir 300 mg Capsule (Abbott Laboratories, USA)
Interventions
NameTypeDescription
Cefdinir 300 mg Capsule (Sandoz, Austria)DRUG -
Omnicef Cefdinir 300 mg Capsule (Abbott Laboratories, USA)DRUG -
Cefdinir 250 mg/5 ml Suspension (Sandoz, Austria)DRUG -
Omnicef Cefdinir 250 mg/5 ml Suspension (Abbott Laboratories, USA)DRUG -
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Eligibility Criteria
Age Range18 Years — 56 Years
SexALL
Healthy VolunteersYes

Inclusion Criteria: * No clinically significant abnormal finding on physical exam, medical history, or clinical laboratory results on screening. Exclusion Criteria: * Positive test results for HIV or hepatitis B or C. * Treatment for drug or alcohol dependence.

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