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AHT956

Phase 1

Healthy | Small molecule | Other |Novartis AG|Last Updated: Jun 22, 2007

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment42

FDA Designations

No designations recorded

Clinical trial landscape

AHT956 · 1 trial · 1 indication

Phase 1 1
NCT00410228Study to Explore the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AHT956 in Healthy SubjectsHealthy
COMPLETED42 Analytics
PHASE1COMPLETED
Study to Explore the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AHT956 in Healthy Subjects
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Study Endpoints

Primary Endpoints

Safety, tolerability of ascending single doses of AHT956 in healthy subjects
MTD (Maximum Tolerated Dose)

Secondary Endpoints

Pharmacokinetics of single oral doses of AEB071
Inhibition of T-cell function and lymphocytes proliferation following single rising oral of AHT956
Pharmacokinetic/pharmacodynamic relationship of single rising oral doses of AHT956 at the end of study
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
AHT956DRUG -
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Eligibility Criteria

Age Range18 Years to 45 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Healthy male and female subjects age 18 to 45 years of age included, and in good health as determined by past medical history, physical examination, vital signs, electrocardiogram, and laboratory tests at screening. * Vital signs must be within the following ranges: oral body ...

Countries:Switzerland
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Frequently asked questions about AHT956

What is AHT956 used for?

AHT956 is an investigational small molecule being studied in healthy volunteers. It is not approved for any disease and is in Phase 1 clinical development. The only completed trial explored its safety, tolerability, pharmacokinetics, and pharmacodynamics after oral administration in healthy subjects.

Who makes AHT956?

AHT956 is being developed by Novartis AG, a multinational pharmaceutical company traded on the New York Stock Exchange under the ticker NVS. The company sponsored the Phase 1 study of this investigational small molecule in healthy volunteers.

What phase is AHT956 in?

AHT956 is in Phase 1 clinical development. A single Phase 1 study has been completed, involving 42 healthy participants in Switzerland. The drug remains investigational and has not been approved by regulatory authorities for any use.

What clinical trials is AHT956 in?

AHT956 has one completed clinical trial, registered as NCT00410228. The study, titled "Study to Explore the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AHT956 in Healthy Subjects," enrolled 42 healthy adults aged 18 years and older in Switzerland.

Is AHT956 FDA approved?

AHT956 is not FDA approved. It is an investigational drug that has completed a Phase 1 trial in healthy volunteers. The drug is still in clinical development and has not been authorized for marketing or use in any patient population.