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Novo Nordisk A/S

NVOFDA catalysts, PDUFA dates & pipeline intelligence
$40.45
▲ +0.45 · +1.13%

Financials

Last updated
Revenue
R&D Expenses
Operating CF
Total Assets
Total Liabilities
Equity
Shares Out.
D/E Ratio
Quarterly Cash
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52W LOW $35.1252W HIGH $64.16
Volume
11.18 M
Value Traded
452.64 M
Short % Float
1.12%
Days to Cover
3.1
+4.6%Week
+7.75%1 Month
-8.65%3 Month
-9.85%6 Month
+10.33%5 Year
+28,000%All Time

Cash Data

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  • SEC Filing

Key Stats

Market Cap
180.61 B
EPS (TTM)
4.27
P/E Ratio
9.48
Ent. Value
218.18 B
Total Shares
4.46 B
Float Shares
3.35 B
Insiders
0.01%
Institutions
9.78%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 3 data presentation
semaglutide (once-weekly subcutaneous)
Obesity in children aged 6 to under 12 years
Phase 3PeptidesEndocrine System
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

NVO Catalyst Timeline

Dated clinical, regulatory and corporate events for Novo Nordisk A/S

Catalyst Timeline

Dated clinical, regulatory & corporate events for Novo Nordisk A/S

83Total events
10Upcoming
35Tier-1 (high impact)
2025 to 2029Coverage

Upcoming catalysts 2

T2Product Launch
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T1Full Results
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SemaglutideApproved

Event history 50

●Quarterly UpdateCorporate
Share repurchase transactions executed 5-9 October 2026
▼Timing GuidanceDenecimigFiledPresentation
FDA informed Novo denecimig BLA review is still ongoing with no new timeline for regulatory action
haemophilia Asource ↗
▼Approval Delay AnnouncedDenecimigFiledFDA Decision
FDA informed Novo that denecimig BLA review is extended due to ongoing facility remediation activities
haemophilia Asource ↗
●Quarterly UpdateCorporate
Weekly share repurchase transactions reported (28 September – 2 October 2026)
▲Additional DataSemaglutideApprovedClinical Data
Post hoc analysis of STEP UP sub-population shows semaglutide reduced liver fat to normal levels in 9 of 10 adults
Obesity with excess liver fatsource ↗
▲Oral PresentationSemaglutideApprovedPresentation
STEP UP pooled liver analysis presented at EASD Annual Meeting 2026
Obesity with excess liver fatsource ↗
▲Topline ReadoutCagriSemaFiledClinical Data
REIMAGINE 1 MRI sub-study data presented at EASD 2026 showing reductions in abdominal, liver and pancreas fat with 14.3% weight reduction at week 40
Early type 2 diabetessource ↗
●Quarterly UpdateCorporate
Cumulative repurchases since 4 February 2026 total 35,379,179 B shares
▲Partnership / LicenseCorporate
Orbis Medicines enters multi-target drug discovery partnership with Novo Nordisk worth up to USD 1.4 billion
cardiometabolic diseasessource ↗
▲CHMP Positive OpinionDenecimigFiledEx-US Regulatory
Denecimig received a positive CHMP opinion
haemophilia Asource ↗
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Past FDA Catalysts and PDUFA Decisions

How NVO actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-10-23Awiqli Flextouch (insulin icodec) PDUFA Date ApprovedPDUFA
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Commercial Value
Valuation Signal
66
Drugs Scored
rNPV / MCap
Top Drug
Top 1%
Large Pharma
(rank 8 of 674)
Percentile Rank
Commercial products (revenue basis: latest annual revenue in its 20-F, converted from DKK to USD, to Dec 2025; product lines from the latest annual filing)
ProductRevenuePrior periodChange
Ozempic
Wegovy
Rybelsus
NovoRapid And NovoLog
Tresiba
NovoSeven
Ryzodeg
NovoMix And NovoLog Mix
Xultophy
Saxenda
Victoza
Fiasp
Top 12 of 17 product lines shown.
Showing 96 of 279 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
NNC0487-0111 Small moleculeNCT07535307Diabetes MellitusPhase 3 RECRUITING 710Dec 6, 2027
Cagrilintide Small moleculeNCT07220759OverweightPhase 3 ACTIVE NOT_RECRUITING 2,609Jun 30, 2027
NNC0487-0111 Small moleculeNCT07503210ObesityPhase 3 ACTIVE NOT_RECRUITING 10,180Jul 4, 2028
Cagrilintide Small moleculeNCT05567796ObesityPhase 3 ACTIVE NOT_RECRUITING 6,004Oct 19, 2026
Insulin icodec Small moleculeNCT07076199Diabetes Mellitus, Type 1Phase 3 ACTIVE NOT_RECRUITING 1,549Mar 1, 2027
Cagrilintide Small moleculeNCT05669755Cardiovascular DiseasePhase 3 ACTIVE NOT_RECRUITING 7,101Oct 14, 2027
CagriSema Small moleculeNCT07184086ObesityPhase 3 ACTIVE NOT_RECRUITING 3,207Feb 9, 2028
Zenagamtide Small moleculeNCT07668401ObesityPhase 3 NOT YET_RECRUITING 400Jan 11, 2029
Zenagamtide Small moleculeNCT07815067OverweightPhase 3 RECRUITING 1,980Jun 12, 2028
Zenagamtide Small moleculeNCT07861100Cardiovascular RiskPhase 3 NOT YET_RECRUITING 8,500Sep 16, 2030
Zenagamtide Small moleculeNCT07797335Type 2 DiabetesPhase 3 RECRUITING 1,778Sep 20, 2028
UBT251 Small moleculeNCT07710729OverweightPhase 2 RECRUITING 373Apr 27, 2027
UBT251 Small moleculeNCT07668388Diabetes Mellitus, Type 2Phase 2 RECRUITING 300Nov 15, 2027
NNC0662-0419 Small moleculeNCT07525791OverweightPhase 2 ACTIVE NOT_RECRUITING 465Jun 18, 2027
NNC0662-0419 Small moleculeNCT07639021ObesityPhase 2 ACTIVE NOT_RECRUITING 233Jun 14, 2027
NNC0662-0419 Small moleculeNCT07415954Diabetes Mellitus, Type 2Phase 2 RECRUITING 270Oct 1, 2027
NNC0519-0130 Small moleculeNCT06717698Chronic Kidney DiseasePhase 2 RECRUITING 465Sep 17, 2026
UBT251 Small moleculeNCT07710768ObesityPhase 1 RECRUITING 44Apr 7, 2027
Ziltivekimab Monoclonal antibodyNCT06200207Heart FailurePhase 3 ACTIVE NOT_RECRUITING 673Jan 8, 2027
Ziltivekimab Monoclonal antibodyNCT06118281Cardiovascular RiskPhase 3 ACTIVE NOT_RECRUITING 10,000Jan 29, 2027
Ziltivekimab Monoclonal antibodyNCT07301034Myocardial InfarctionPhase 3 RECRUITING 332Feb 24, 2029
Ziltivekimab Monoclonal antibodyNCT07276282Coronary Artery DiseasePhase 3 RECRUITING 332Dec 1, 2028
NNC9836-0001 Small moleculeNCT07896109Diabetes Mellitus, Type 2Phase 1 NOT YET_RECRUITING 121Jul 26, 2028
NNC1679-0001 Small moleculeNCT07570992Diabetes Mellitus, Type 2Phase 1 RECRUITING 58Jun 25, 2028
NNC0194-0499 Small moleculeNCT07087795Diabetes Mellitus, Type 1Phase 1 ACTIVE NOT_RECRUITING 96Sep 25, 2026
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Clinical Trial Results

Readouts, endpoints and source filings for every NVO program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
CagriSema obesity and type 2 diabetesPhase 3a2026-09-3022.4% reduction in body weight versus placebo at 52 weeks; 14.3% body-weight reduction at week 40; 14.2% body-weight reduction with CagriSema at week 68Read MoreNovo’s investigational obesity and diabetes drug CagriSema reduces ‘food noise’ and shows benefits in organ and bone health · EASD 2026Read More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
INTEGRAL HEALTH ASSET MANAGEMENT, LLC 1.1 % 28.76 M 600.00 K
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Shares held by hedge funds each quarter, and who bought or sold.

Ownership Trends

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Insider and institutional ownership, quarter by quarter.

NVO Short Interest

Shares sold short, counted twice a month.

1.12%
Short % of Float
of tradable shares sold short
37.4M
Shares Sold Short
+18.4% vs prior count
3.1 Moderate
Days to Cover
trading days of normal volume to buy every short share back
12.1M
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-11-06
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How NVO ranks across every disease it competes in

Competitive Position is a premium feature
See how NVO ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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NVO News

NVO
Oct 26, 2026
NVOGeneral

Novo Nordisk A/S - share repurchase programme

Novo Nordisk has launched a share repurchase programme worth up to DKK 15 billion, starting on 6 May 2026. The company has already repurchased 40,274,179 B shares at an average price of DKK 277.78 per share. As of 23 October 2026, Novo Nordisk holds a total of 54,314,876 B shares as treasury shares.

Read more →
NVO
Oct 5, 2026
NVOGeneral

Novo Nordisk A/S – Share repurchase programme

Novo Nordisk has initiated a share repurchase program on May 6, 2026, as part of a larger initiative to buy back shares worth up to DKK 15 billion over 12 months. As of October 2, 2026, the company has repurchased 36,604,179 B shares, totaling approximately DKK 10.25 billion. This move is aimed at enhancing shareholder value and reflects the company's strong market position.

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NVO
Oct 2, 2026
NVOFDA Updates

Novo provides update on the denecimig Biologics License Application (BLA) in the US

Novo Nordisk announced that the FDA's review of the Biologics License Application for denecimig, a treatment for haemophilia A, is ongoing. The FDA has not identified any deficiencies in the clinical data but has extended the review due to facility remediation activities. Novo aims to launch denecimig in the US in the first half of 2027, despite the delays.

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NVO
Oct 1, 2026
NVOPhases

Novo’s Wegovy® (semaglutide) reduced liver fat to normal levels in 9 out of 10 adults with obesity and excess liver fat – EASD2026

Novo Nordisk reported that its drug Wegovy® (semaglutide) significantly reduced liver fat in adults with obesity. In a sub-population analysis from the STEP UP trial, 88.5% of participants with elevated liver fat achieved normal levels after 72 weeks of treatment. The average liver fat percentage decreased from 8.8% to 3.1%, indicating improved liver health.

Read more →
NVO
Sep 30, 2026
NVOPhases

Novo’s investigational obesity and diabetes drug CagriSema reduces ‘food noise’ and shows benefits in organ and bone health – EASD 2026

Novo Nordisk presented promising new data on CagriSema at the EASD Annual Meeting 2026. The investigational drug demonstrated significant effects on reducing cravings and improving eating behavior in individuals with obesity. Additionally, it showed beneficial impacts on abdominal fat and bone health in adults with type 2 diabetes. These findings suggest CagriSema may address underlying factors of obesity and diabetes beyond weight loss.

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NVO
Sep 29, 2026
NVOGeneral

Novo and Hengrui Pharma enter exclusive license agreement for once-weekly oral GLP-1/GIP dual receptor agonist HRS-1596

Novo Nordisk has entered an exclusive license agreement with Hengrui Pharma for HRS-1596, a phase 1-ready GLP-1/GIP dual receptor agonist. The deal is valued at up to $2.6 billion, including a $300 million upfront payment. HRS-1596 aims to offer once-weekly oral dosing, potentially enhancing treatment convenience for obesity and type 2 diabetes. The agreement excludes certain regions in Asia and is subject to regulatory approvals.

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NVO
Sep 23, 2026
NVOPhases

Novo's CagriSema delivers superior weight loss versus tirzepatide in REIMAGINE 5 trial

Novo Nordisk announced positive topline results from the phase 3 REIMAGINE 5 and REDEFINE 9 trials, demonstrating that CagriSema 1.0 mg/1.0 mg resulted in superior weight loss compared to tirzepatide 5 mg in adults with type 2 diabetes. Additionally, CagriSema showed significant weight reduction versus placebo in overweight or obese participants. The treatment was well tolerated, with a safety profile consistent with previous studies.

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NVO
Sep 22, 2026
NVOGeneral

Novo and UNICEF expand partnership to support a healthier start for more than 80 million children

Novo Nordisk and UNICEF have announced a four-year expansion of their partnership to combat childhood obesity, targeting over 80 million children in seven countries. The initiative will focus on creating healthier environments and promoting better nutrition and physical activity. Novo is investing $18 million from 2026 to 2030 to support this program, which aims to implement evidence-based policies and interventions.

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NVO
Sep 21, 2026
NVOConferences/Events
▼ -8%on this newsshared move

Highlights to be presented at Novo’s Capital Markets Day 2026

Novo Nordisk is hosting its Capital Markets Day in London, outlining its corporate strategy and ambitions for 2030. Key highlights include plans to launch more than five multi-blockbuster drugs and to serve over 60 million patients globally. The company aims for sustainable growth and attractive returns while maintaining a stable operating margin.

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NVO
Sep 18, 2026
NVOFDA Updates

Novo’s once-weekly Sogroya® (somapacitan) receives positive CHMP opinion in Europe for children with idiopathic short stature (unexplained shortness)

Novo Nordisk's Sogroya® (somapacitan) has received a positive opinion from the CHMP for treating idiopathic short stature (ISS) in children. This would mark the first approved growth hormone therapy for ISS in the EU, addressing a significant unmet need. The recommendation follows previous approvals for other conditions, with a decision from the European Commission expected later this year.

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NVO
Sep 17, 2026
NVOFDA Updates

Novo: CHMP recommends EU approval of FREHEMGO® (denecimig), the first factor VIIIa mimetic offering monthly, once every two weeks and weekly dosing in a pre-filled pen, for the treatment of haemophilia A

Novo Nordisk's FREHEMGO® (denecimig) has received a positive recommendation from the CHMP for EU approval to treat haemophilia A in both adults and children. This innovative treatment offers flexible dosing options and has shown significant efficacy in clinical trials, reducing annualized bleeding rates. The company plans to launch FREHEMGO® in Europe starting in late 2026.

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NVO
Sep 17, 2026
NVOGeneral

Orbis Medicines Enters Multi-Target Drug Discovery Partnership with Novo Nordisk Worth up to USD 1.4 Billion

Orbis Medicines has entered a strategic partnership with Novo Nordisk to develop oral macrocycle therapeutics targeting cardiometabolic diseases. This collaboration allows for the acceleration of creating a new class of medicines. The agreement could yield up to USD 1.4 billion, reflecting significant investment in innovative therapies.

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NVO
Sep 16, 2026
NVOGeneral

Novo and Anthropic will collaborate to advance drug discovery with Claude

Novo Nordisk has announced a collaboration with Anthropic to enhance drug discovery through AI. The partnership aims to address specific scientific challenges and improve R&D productivity. By utilizing Anthropic's models, Novo seeks to accelerate the development of new medicines and strengthen AI-driven software development. The collaboration emphasizes responsible AI application and data governance.

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NVO
Sep 16, 2026
NVOConferences/Events

Novo to share real-world and clinical data including Wegovy® pill, and cardiometabolic pipeline progress with next-generation amylin treatments at EASD 2026

Novo Nordisk will present new data at the EASD 2026 meeting, showcasing advancements in their cardiometabolic portfolio, including insights on the Wegovy® pill and CagriSema. The data covers various conditions such as obesity, type 2 diabetes, and cardiovascular diseases. Key presentations will include real-world evidence and innovative findings on appetite regulation and body composition.

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NVO
Sep 14, 2026
NVOGeneral

Novo Nordisk enters next chapter to bring better health to more people, supported by ‘Novo’ rebrand and updated corporate culture

Novo Nordisk has launched a rebranding initiative centered on the theme 'Lasting Health Starts Now' and introduced a new corporate culture called 'The Novo Way'. This rebrand aims to enhance engagement with stakeholders and improve health accessibility. The company emphasizes its commitment to innovation and patient safety while preparing for a competitive market landscape.

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About Novo Nordisk A/S

69,500 employees novonordisk.com
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