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Syringe Pump

Phase 1

Healthy Participants | Unknown | Other |Novo Nordisk A/S|Last Updated: Aug 18, 2026

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindCONTROLLED
Total Trials1
Total Enrollment100

FDA Designations

No designations recorded

Clinical trial landscape

Syringe Pump · 1 trial · 1 indication

Phase 1 1
NCT07769489Study to Assess Tolerability of Injecting Larger Volumes (2-5 mL) Subcutaneously at Different Rates: Participant Experience and AcceptanceHealthy Participants
NOT YET_RECRUITING100 Analytics
PHASE1NOT YET_RECRUITING
Study to Assess Tolerability of Injecting Larger Volumes (2-5 mL) Subcutaneously at Different Rates: Participant Experience and Acceptance
Healthy ParticipantsUnlock trial analytics

Study Endpoints

Primary Endpoints

Injection pain rated on a Visual Analogue Scale (VAS)
1 minute (±1 minute) from the injection initiation

The VAS scale consists of a 100 mm line on a paper where 1 will be no pain and 100 being the worst pain imaginable. The VAS response will be recorded in millimetres (mm).

Injection pain rated on a VAS
9 minutes (±1minute) from the injection initiation

The VAS scale consists of a 100 mm line on a paper where 1 will be no pain and 100 being the worst pain imaginable. The VAS response will be recorded in mm.

Secondary Endpoints

Acceptance of pain for each injection (including the needle insertions only) as a binary measure
1 minute (±1 minute) from the injection initiation
Back flow at the injection site
5 minutes (±1 minute) from the injection initiation
Number of acute injection site reactions (haematoma, haemorrhage, bruising, erythema and oedema formation) after each injection
9 minutes (±1 minute) from the injection initiation
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Study Design & Arms

AllocationRANDOMIZED
MaskingTRIPLE
ModelCROSSOVER
PurposeOTHER

Treatment Arms

ArmTypeDescription
Pilot cohortEXPERIMENTALParticipants will receive subcutaneous injections and infusions of sodium chloride (NaCl) solution in varying combinations of speed and volume at different abdominal sites in a randomised sequence. A syringe pump with an attached syringe will be used for delivery of subcutaneous injections and infusions.
Main cohortEXPERIMENTALParticipants will receive subcutaneous injections and infusions of sodium chloride (NaCl) solution in varying combinations of speed and volume (that have passed safety assessment in pilot cohort) at different abdominal sites in a randomised sequence. A syringe pump with an attached syringe will be used for delivery of subcutaneous injections and infusions.

Interventions

NameTypeDescription
Syringe PumpDEVICEDevice used for delivery of subcutaneous injections and infusions of NaCl solution.
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Eligibility Criteria

Age Range18 Years to 64 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion criteria: * Informed consent obtained before any study-related activities. Study-related activities are any procedures that are carried out as part of the study, including activities to determine suitability for the study. * Healthy male or female participants as judged by the investigato...

Countries:Denmark
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Recent Changes (Last 90 Days)

LOWAug 19, 2026NCT07769489NEW_TRIAL: changed
LOWAug 19, 2026NCT07769489NEW_TRIAL: changed
LOWAug 19, 2026NCT07769489NEW_TRIAL: changed

Frequently asked questions about Syringe Pump

What is Syringe Pump used for?

Syringe Pump is an investigational drug being studied in healthy participants. It is currently in Phase 1 clinical development, with a trial assessing the tolerability of injecting larger volumes (2-5 mL) subcutaneously at different rates, focusing on participant experience and acceptance.

Who makes Syringe Pump?

Syringe Pump is being developed by Novo Nordisk A/S, a biopharmaceutical company traded on the stock exchange under the ticker NVO. The company is conducting a Phase 1 clinical trial to evaluate the drug's tolerability in healthy participants.

What phase is Syringe Pump in?

Syringe Pump is in Phase 1 clinical development. It is an investigational drug, not yet approved by regulatory authorities. The ongoing Phase 1 trial is designed to assess tolerability and participant experience with subcutaneous injections of larger volumes.

What clinical trials is Syringe Pump in?

Syringe Pump is being studied in one Phase 1 clinical trial with the identifier NCT07769489. This trial, which is not yet recruiting, aims to enroll 100 healthy participants in Denmark to evaluate the tolerability of injecting larger volumes (2-5 mL) subcutaneously at different rates.

Is Syringe Pump FDA approved?

Syringe Pump is not FDA approved. It is an investigational drug currently in Phase 1 clinical development. The drug is being studied in healthy participants to assess tolerability, but it has not yet received regulatory approval for any use.