Recent Updates
Recently added Catalysts

NPH insulin

Phase 3

Diabetes Mellitus, Type 1 | Small molecule | Metabolic |Novo Nordisk A/S|Last Updated: Jul 18, 2017

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedACTIVE_CONTROLLEDBiomarker
Total Trials1
Total Enrollment752
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT03220425Evaluation of the Efficacy and Safety of Insulin Detemir Compared With That of NPH Insulin in Subjects With Type 1 Diabetes.PHASE3 COMPLETED 752Feb 1, 2001Nov 12, 2001Jul 18, 201793 Australia, Belgium +8
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
The change in the level of glycosylated haemoglobin(HbA1c)
From start of treatment visit 2 (week 0) until end of treatment visit 8 (week 26)
Unlock Study Endpoints
Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
Treatment Arms
ArmTypeDescription
Insulin detemirEXPERIMENTAL -
NPH insulinACTIVE_COMPARATOR -
Interventions
NameTypeDescription
Insulin detemirDRUG -
NPH insulinDRUG -
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites93

Inclusion Criteria: * Signed and dated informed consent obtained before any trial-related activities * Type 1 diabetes diagnosed and classified according to aetiology * Duration of type 1 diabetes equal to or more than 12 months * Glycosylated haemoglobin less than or equal to 12 percent based on a...

Countries:AustraliaBelgiumDenmarkFinlandFranceIrelandNetherlandsNorwaySwedenUnited Kingdom
Unlock Eligibility Criteria