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NN9925

Phase 1

Diabetes | Small molecule | Metabolic |Novo Nordisk A/S|Last Updated: Feb 28, 2017

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindCONTROLLED
Total Trials1
Total Enrollment70

FDA Designations

No designations recorded

Clinical trial landscape

NN9925 · 1 trial · 3 indications

Phase 1 1
NCT01087645A Two Part Trial Investigating the Safety of NN9925 in Healthy Male SubjectsDiabetes
COMPLETED70 Analytics
PHASE1COMPLETED
A Two Part Trial Investigating the Safety of NN9925 in Healthy Male Subjects
DiabetesUnlock trial analytics

Study Endpoints

Primary Endpoints

Number and severity of adverse events (AEs) recorded
from dosing to Day 22

Secondary Endpoints

The uptake in blood of oral NN9925
from 0 to 504 hours
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Trial part 1EXPERIMENTAL -
Trial part 2EXPERIMENTAL -

Interventions

NameTypeDescription
NN9925 (oral)DRUGSubjects will be randomised to receive a single dose of NN9925, at escalating dose levels. Progression to next dose will be based on safety evaluation
NN9925 (i.v.)DRUGAs an active comparator, one standard dose will be given i.v. (into the vein) at one study visit
placeboDRUGSubjects will receive a single dose of placebo as a comparator to NN9925, at all dose levels
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Eligibility Criteria

Age Range18 Years to 50 Years
SexMALE
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Male subjects with good general health as judged by the physician * Body weight of 65-95 kg (both inclusive) * Body Mass Index (BMI) of 18.5-27.5 kg/m2 (both inclusive) Exclusion Criteria: * Known or suspected allergy to trial product or related products * Acute infection or...

Countries:United Kingdom
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Competitive Landscape -Diabetes Complications 6 trials (matched to "Diabetes")

Frequently asked questions about NN9925

What is NN9925 used for?

NN9925 is an investigational small molecule being developed for diabetes, including type 2 diabetes. It is currently in Phase 1 clinical development and is not yet approved. The drug is being studied for its safety and tolerability in healthy subjects.

What does NN9925 target?

NN9925 is a small molecule being developed for diabetes. Its specific molecular target has not been disclosed in available information. The drug is in Phase 1 clinical trials to evaluate its safety and tolerability.

Who makes NN9925?

NN9925 is being developed by Novo Nordisk A/S, a pharmaceutical company listed on the stock exchange under the ticker NVO. The drug is currently in Phase 1 clinical development for diabetes.

What phase is NN9925 in?

NN9925 is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. One Phase 1 trial has been completed, and the drug is being studied for diabetes.

What clinical trials is NN9925 in?

NN9925 has one completed Phase 1 clinical trial, NCT01087645, titled 'A Two Part Trial Investigating the Safety of NN9925 in Healthy Male Subjects.' The trial enrolled 70 healthy male participants in the United Kingdom and was a randomized, double-blind, controlled study.

Is NN9925 the same as any other drug?

No alternative names for NN9925 have been disclosed. The drug is being developed by Novo Nordisk A/S under the code name NN9925 and is currently in Phase 1 clinical trials for diabetes.