Recent Updates
Recently added Catalysts

NN9924

Phase 1

Diabetes | Small molecule | Metabolic |Novo Nordisk A/S|Last Updated: Jan 3, 2019

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedDouble-BlindCONTROLLED
Total Trials1
Total Enrollment155
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT01037582A Two Part Trial Investigating the Safety of NN9924 in Healthy Male SubjectsPHASE1 COMPLETED 155Dec 17, 2009May 7, 2010Jan 3, 20191 United Kingdom
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Number and severity of adverse events (AEs) recorded
from dosing to Day 22
Secondary Endpoints
The uptake in blood of oral NN9924 compared to i.v. and s.c. administration of the same compound
from 0 to 504 hours
Unlock Study Endpoints
Study Design & Arms
AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
Trial part 1EXPERIMENTAL -
Trial part 2EXPERIMENTAL -
Interventions
NameTypeDescription
NN9924 (oral)DRUGSubjects will be randomized to receive a single dose of NN9924, at escalating dose levels. Progression to next dose will be based on safety evaluation.
placeboDRUGSubjects will receive a single dose of placebo as a comparator to NN9924, at all dose levels.
NN9924 (s.c.)DRUGAs an active comparator, one standard dose will be given s.c. (under the skin) at one study visit
NN9924 (i.v.)DRUGAs an active comparator, one standard dose will be given i.v. (into the vein) at one study visit.
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — 50 Years
SexMALE
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Male subjects with good general health as judged by the Investigator * Body weight of 65.0-95.0 kg (both inclusive) * Body Mass Index (BMI) of 18.5-27.5 kg/m\^2 (both inclusive) Exclusion Criteria: * Known or suspected allergy to trial product or related products * Acute inf...

Countries:United Kingdom
Unlock Eligibility Criteria