Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT07448623 | A Research Study to Look at the Distribution and Effects of Coramitug on Amyloid Deposits in Heart Tissue Using PET/CT Imaging in People With ATTR Amyloidosis. | PHASE1 | RECRUITING | 14 | — | — | Mar 2, 2026 | Jul 25, 2028 | Apr 13, 2026 | 1 | Netherlands |
Measured as ratio.
Measured as milliliter per minute per centimeter cube (mL/min/cm\^3).
Measured as percentage (%).
| Arm | Type | Description |
|---|---|---|
| Cohort 1 | EXPERIMENTAL | The cohort includes participants that will be evaluated for the cardiac uptake of 89Zr coramitug. |
| Cohort 2 | EXPERIMENTAL | The cohort includes participants to evaluate the sink effect (if observed in cohort 1) and also evaluate competitive binding between 89Zr-coramitug and different dose levels of coramitug. |
| Name | Type | Description |
|---|---|---|
| Coramitug | DRUG | Coramitug will be administered intravenously |
Inclusion Criteria: * Informed consent obtained before any study-related activities. Study-related activities are any procedures that are carried out as part of the study, including activities to determine suitability for the study. * Male or female. * Age greater than or equal to (≥) 60 years or a...