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Amicidin-β

Phase 1

Surgical Wound Infection | Small molecule | Infectious Disease |Novo Nordisk A/S|Last Updated: May 6, 2026

Target and mechanism

ModalitySmall molecule

Also known as Amicidin-β topical solution - 15 mL

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment44

FDA Designations

No designations recorded

Clinical trial landscape

Amicidin-β · 1 trial · 2 indications

Phase 1 1
NCT07379684A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound InfectionsSurgical Wound Infection
RECRUITING44 Analytics
PHASE1RECRUITING
A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections
Surgical Wound InfectionUnlock trial analytics

Study Endpoints

Primary Endpoints

Overall comparison of treatment emergent adverse events (TEAES) of combined SOC + Amicidin-β topical solution recipients to SOC only recipients across 3 cohorts.
From Day 1 to Day 30

Secondary Endpoints

Number of participants with Treatment Emergent Adverse Events (TEAEs) by severity according to the study protocol.
From Day 1 to Day 30
Measurement of systemic absorption of Amicidin-β recipients.
From Day 1 to Day 3
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelSEQUENTIAL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
SOC + Amicidin-β topical solution - 15 mLEXPERIMENTALIn addition to Standard of Care (SOC), patients will receive Amicidin-β topical solution - 15 mL immediately prior to wound closure/dressing, with rinsing out with saline.
SOC + Amicidin-β topical solution - 50 mL - Scheme 1EXPERIMENTALIn addition to Standard of Care (SOC), patients will be receive Amicidin-β topical solution - 50 mL immediately prior to wound closure/dressing, with rinsing out with saline
SOC + Amicidin-β topical solution - 50 mL - Scheme 2EXPERIMENTALIn addition to Standard of Care (SOC), patients will be receive Amicidin-β topical solution - 50 mL immediately prior to wound closure/dressing, without rinsing out with saline
SOCACTIVE_COMPARATORPatients will receive Standard of Care (SOC) only

Interventions

NameTypeDescription
Amicidin-β topical solution - 15 mLDRUGAmicidin-β topical solution for local administration - 15 mL
Amicidin-β topical solution - 50 mLDRUGAmicidin-β topical solution for local administration - 50 mL
Standard of Care (SOC)DRUGPer institutional Standard Of Care
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Eligibility Criteria

Age Range18 Years to 79 Years
SexALL
Healthy VolunteersNo
Study Sites4

Main Inclusion Criteria: * Body Mass Index between 18.5 kg/square meter and 39.9kg/square meter * Surgical or traumatic wound determined by the Investigator to be infected within 90 days of surgery or trauma, with longest dimension between 3 and 15 cm. The diagnosis should include one or more of th...

Countries:United States
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Frequently asked questions about Amicidin-β

What is Amicidin-β used for?

Amicidin-β is an investigational small molecule being developed for the treatment of surgical wound infections. It is formulated as a topical solution and is currently in Phase 1 clinical development. The drug is being studied in patients with surgical or traumatic wound infections.

What does Amicidin-β target?

Amicidin-β is a small molecule, but its specific molecular target has not been disclosed. The drug is being developed as a topical solution for infectious disease, specifically for surgical wound infections. Its mechanism of action is not publicly detailed at this time.

Who makes Amicidin-β?

Amicidin-β is being developed by Novo Nordisk A/S, a pharmaceutical company listed on the stock exchange under the ticker NVO. The drug is currently in Phase 1 clinical trials for the treatment of surgical wound infections.

What phase is Amicidin-β in?

Amicidin-β is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. The ongoing Phase 1 trial is actively recruiting participants to evaluate the drug's safety and efficacy in patients with wound infections.

What clinical trials is Amicidin-β in?

Amicidin-β is being studied in a Phase 1 clinical trial with the identifier NCT07379684. This trial is titled "A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections" and is currently recruiting participants in the United States. The study plans to enroll 44 patients aged 18 years and older.

Is Amicidin-β the same as Amicidin-β topical solution - 15 mL?

Yes, Amicidin-β is also known as Amicidin-β topical solution - 15 mL. This alternative name refers to the specific formulation and packaging of the drug being tested in clinical trials. Both names refer to the same investigational drug product developed by Novo Nordisk.