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Disulfiram

Phase 2

Alcohol-Related Disorders | Small molecule | Other |National Healthcare Corp.|Last Updated: Jun 18, 2020

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment -

FDA Designations

No designations recorded

Clinical trial landscape

Disulfiram · 1 trial · 2 indications

Phase 2 1
NCT00000278Disulfiram for Cocaine-Alcohol Abuse - 3Alcohol-Related Disorders
COMPLETED- Analytics
PHASE2COMPLETED
Disulfiram for Cocaine-Alcohol Abuse - 3
Alcohol-Related DisordersUnlock trial analytics

Study Endpoints

Primary Endpoints

Side effects
Cocaine effects
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Study Design & Arms

PurposeTREATMENT

Interventions

NameTypeDescription
DisulfiramDRUG -
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Eligibility Criteria

Age Range18 Years to 50 Years
SexALL
Healthy VolunteersNo
Study Sites1

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Countries:United States
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Frequently asked questions about Disulfiram

What is Disulfiram used for?

Disulfiram is used for alcohol-related disorders, specifically as a treatment for alcohol dependence. It is a small molecule being developed by National Healthcare Corp. (NHC). The drug is currently in Phase 2 clinical development, though the available trial data is from a completed study.

What does Disulfiram target?

Disulfiram works by interfering with alcohol metabolism, causing unpleasant effects when alcohol is consumed. It inhibits the enzyme acetaldehyde dehydrogenase, leading to an accumulation of acetaldehyde, which produces aversive symptoms. This mechanism is intended to discourage alcohol consumption in individuals with alcohol-related disorders.

Who makes Disulfiram?

Disulfiram is being developed by National Healthcare Corp., which trades under the ticker NHC. The company is conducting clinical research on this small molecule for the treatment of alcohol-related disorders. The drug is currently in Phase 2 development.

What phase is Disulfiram in?

Disulfiram is in Phase 2 clinical development. It is an investigational drug, not yet approved by the FDA. The available trial data includes one completed Phase 2 study, and the drug is being studied for alcohol-related disorders.

What clinical trials is Disulfiram in?

Disulfiram has one completed clinical trial, NCT00000278, titled 'Disulfiram for Cocaine-Alcohol Abuse - 3'. This Phase 2 study was conducted in the United States and enrolled adults aged 18 years and older. The trial was uncontrolled and not randomized or double-blinded.

Is Disulfiram the same as Antabuse?

Disulfiram is the generic name for the drug also known as Antabuse. It is a small molecule used to treat alcohol-related disorders. The drug is currently in Phase 2 development by National Healthcare Corp. (NHC) for this indication.