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Neuphoria Therapeutics Inc.

NEUPFDA catalysts, PDUFA dates & pipeline intelligence
$3.35
▲ +0.05 · +1.52%

Financials

Last updated
Revenue
R&D Expenses
Operating CF
Total Assets
Total Liabilities
Equity
Shares Out.
D/E Ratio
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Quarterly Cash
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52W LOW $3.1952W HIGH $17.19
Volume
23.67 K
Value Traded
59.81 K
Short % Float
0.39%
Days to Cover
1.6
+0.9%Week
-9.7%1 Month
+1.52%3 Month
-33.4%6 Month
-97.92%5 Year
-97.92%All Time

Cash Data

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  • Monthly Burn
  • Burn Trend
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  • SEC Filing

Key Stats

Market Cap
18.11 M
EPS (TTM)
-2.49
P/E Ratio
-
Ent. Value
-1.90 M
Total Shares
5.41 M
Float Shares
5.14 M
Insiders
5.02%
Institutions
41.51%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 2 data readout
iSCIB1+
advanced melanoma
Fast Track
Phase 2VaccinesOncology
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

NEUP Catalyst Timeline

Dated clinical, regulatory and corporate events for Neuphoria Therapeutics Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for Neuphoria Therapeutics Inc.

162Total events
6Upcoming
34Tier-1 (high impact)
2021 to 2027Coverage

Upcoming catalysts 2

T2Timing Guidance
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T1Acquisition
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Event history 50

◆AcquisitionCorporate
Scancell to acquire Neuphoria in all-share merger
▼Equity OfferingCorporate
Private Placement of $39.1 million
◆Debt Royalty FinancingCorporate
Non-binding term sheet for up to $25 million Debt Financing with BlackRock
◆Management ChangeCorporate
Lynx1 Master Fund LP intends to nominate individuals for election to Board of Directors at 2025 Annual Meeting
▲Quarterly UpdateCorporate
ISS recommends voting for Neuphoria's director nominees
◆Pipeline PrioritizationCorporate
Strategic review of alternatives initiated; R&D expenditures paused for BNC210 in PTSD
●Quarterly UpdateCorporate
Proxy contest and strategic review update
◆Management ChangeCorporate
Proxy contest: Neuphoria recommends voting for its nominees Peter Miles Davies and David Wilson
◆Pipeline PrioritizationCorporate
Initiation of strategic review to maximize stockholder value
◆Quarterly UpdateCorporate
Engaged H.C. Wainwright & Co. as financial advisor for strategic review
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How NEUP actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2025-09-30BNC210 (oral solid tablet) Phase 3 data readout Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Valuation Signal
1
Drugs Scored
rNPV / MCap
Top Drug
Top 45%
Micro Cap
(rank 296 of 657)
Percentile Rank
Showing 3 of 4 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
BNC210 Small moleculeCompletedNCT05193409Social Anxiety DisorderPhase 3 COMPLETED 521Oct 17, 2022
BNC210 Small moleculeCompletedNCT03548194Agitation in the ElderlyPhase 2 COMPLETED 38Apr 24, 2019
BNC210 Small moleculeCompletedNCT04951076Post-Traumatic Stress DisorderPhase 2 COMPLETED 405Aug 14, 2023
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Clinical Trial Results

Readouts, endpoints and source filings for every NEUP program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
BNC210 Post-Traumatic Stress Disorder (PTSD)Phase 2b2023-09-28total patients: 212; primary endpoint p value: 0.048; secondary endpoint depressive symptoms p value: 0.04; secondary endpoint sleep p value: 0.041; adverse events: headache >5%, nausea >5%, fatigue >5%, hepatic enzyme increase 14 (13.3%) patients treated with BNC210 vs 2 (0.19%) in the placebo groupRead MoreBionomics Announces Positive Topline Results from the Phase 2b ATTUNE Clinical Trial of BNC210 in Patients with Post-Traumatic Stress Disorder (PTSD) ATTUNE trial met its primary endpoint showing BNC210 treatment led to Read More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Lynx1 Capital Management LP10% OwnerBuy 639,110 875,328 held$5.14 10/21/2025
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
Ikarian Capital, LLC 0 % 207.33 K 47.44 K
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Shares held by hedge funds each quarter, and who bought or sold.

NEUP Institutional Ownership Trends

NEUP Short Interest

Shares sold short, counted twice a month.

0.39%
Short % of Float
of tradable shares sold short
20.0K
Shares Sold Short
-19.0% vs prior count
1.6 Low
Days to Cover
trading days of normal volume to buy every short share back
12.4K
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How NEUP ranks across every disease it competes in

Competitive Position is a premium feature
See how NEUP ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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NEUP News

NEUP
Jul 23, 2026
NEUPGeneral
▲ +17.7%on this news

Scancell and Neuphoria Therapeutics Announce Merger Agreement and Financing

Scancell and Neuphoria Therapeutics have announced an all-share merger, creating a combined entity that will operate under the Scancell name and seek a Nasdaq listing. The merger, which has been unanimously approved by both companies' boards, aims to advance Scancell's immunotherapy pipeline, particularly the lead program iSCIB1+. The transaction includes significant financing to support a Phase 3 trial for iSCIB1+ in advanced melanoma.

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NEUP
Jun 26, 2026
NEUPGeneral

Neuphoria Responds to the announcement made by London-listed Scancell Holdings plc

Neuphoria Therapeutics has confirmed ongoing discussions with Scancell Holdings plc regarding a potential collaboration. This engagement suggests a strategic move to enhance their development initiatives. The talks indicate a positive outlook for Neuphoria as it seeks to expand its operational capabilities.

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NEUP
Dec 8, 2025
NEUPGeneral
▲ +6.3%on this news

Leading Proxy Advisory Firm ISS Recommends that Shareholders Vote the WHITE Proxy Card FOR Both of Neuphoria’s Director Nominees

Neuphoria Therapeutics Inc. has received a recommendation from Institutional Shareholders Services (ISS) for shareholders to vote for its director nominees on the WHITE proxy card. This recommendation comes amid a proxy contest initiated by Lynx1 Capital Management. Neuphoria's board is recognized for its proactive measures following the Phase 3 trial results of BNC210, which missed its endpoints, prompting a strategic review.

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NEUP
Dec 4, 2025
NEUPGeneral

Neuphoria Responds to Lynx1’s Revised Indication of Interest at a Reduced Price and Premium

Neuphoria Therapeutics has responded to Lynx1's revised interest in acquiring the company at a lower bid of $4.75 per share, which the board deems inadequate. The company is currently conducting a strategic review of alternatives for maximizing stockholder value and has received significant interest from various parties. Neuphoria's board emphasizes the importance of evaluating all proposals while ensuring that their own strategic processes are not overlooked. They encourage stockholders to support their existing board nominees amid the ongoing proxy contest with Lynx1.

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NEUP
Dec 1, 2025
NEUPGeneral

Neuphoria Provides Facts, Exposes False Narratives in Response to Lynx1 Fictions

Neuphoria Therapeutics has released a statement addressing allegations made by Lynx1 Master Fund, which it claims are misleading and intended to distract shareholders. The company urges investors to support its board nominees while disputing Lynx1's criticisms regarding its strategic plans and board actions. Neuphoria asserts it has maintained transparency and has a robust strategic review process. The situation highlights an ongoing proxy contest where shareholder confidence is a significant concern.

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NEUP
Nov 24, 2025
NEUPGeneral

Neuphoria Therapeutics Inc. Sends Letter to Stockholders

Neuphoria Therapeutics Inc. has issued a letter to its stockholders urging them to vote in favor of its two nominated board members at the upcoming 2025 Annual Meeting. The company is undergoing a strategic review aimed at maximizing value for all stockholders, particularly in light of its upcoming clinical trial data. Additionally, Neuphoria is raising capital to ensure financial stability, mitigating risks associated with clinical outcomes and potential takeover threats. The company expresses confidence in its nominated directors' ability to navigate this important phase effectively.

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NEUP
Nov 11, 2025
NEUPGeneral

Neuphoria Announces Initiation of Strategic Review to Maximize Stockholder Value

Neuphoria Therapeutics has initiated a strategic review to explore options for maximizing stockholder value, including potential mergers and acquisitions. The company has engaged H.C. Wainwright & Co. as its financial advisor. Additionally, Neuphoria received an unsolicited acquisition offer from Lynx1 Master Fund LP at $5.20 per share. The review comes after the company halted development of its lead drug candidate, BNC210, due to unmet clinical trial endpoints.

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NEUP
Oct 27, 2025
NEUPGeneral

Neuphoria Therapeutics Adopts Limited-Duration Stockholder Rights Plan to Protect Integrity of Process

Neuphoria Therapeutics has adopted a limited-duration stockholder rights plan to safeguard the integrity of its strategic review process amid significant stock accumulation by certain investors. The plan aims to ensure fair participation for all stockholders and allows the Board time to make informed decisions. However, the company recently halted development of its lead drug candidate following a failed clinical trial.

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NEUP
Oct 20, 2025
NEUPPhases
▼ -68.5%on this news

Neuphoria Therapeutics Provides Update on AFFIRM-1 Phase 3 Trial Evaluating BNC210 for the Acute Treatment of Social Anxiety Disorder

Neuphoria Therapeutics announced that its AFFIRM-1 Phase 3 trial for BNC210 in treating social anxiety disorder failed to meet its primary and secondary endpoints. As a result, the company will halt the development of its SAD program and conduct a strategic review of its operations. Neuphoria will also explore further development of BNC210 for PTSD.

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NEUP
Sep 29, 2025
NEUPPhases

Neuphoria Provides Fiscal Year-End 2025 Financial Results and Business Updates

Neuphoria Therapeutics has achieved the last patient last visit milestone in its AFFIRM-1 Phase 3 trial for BNC-210, aimed at treating social anxiety disorder. The company reported a net loss of $0.4 million for the fiscal year ending June 30, 2025, a significant reduction from the previous year's loss. Neuphoria's cash position is expected to support operations through Q2 2027, with topline data from the trial anticipated in early Q4 2025.

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NEUP
Sep 4, 2025
NEUPPhases
▼ -8.3%on this news

Neuphoria Therapeutics Completes Target Enrollment in Phase 3 AFFIRM-1 Trial of BNC-210 in Social Anxiety Disorder (SAD)

Neuphoria Therapeutics has completed the target enrollment of 332 participants in its Phase 3 AFFIRM-1 trial for BNC-210, a treatment for social anxiety disorder (SAD). The trial is designed to evaluate the safety and efficacy of a single acute dose of BNC-210 compared to a placebo. The company anticipates that Phase 3 data will be available early in the fourth quarter of 2025. BNC-210 has received FDA Fast Track designation, which supports its development for SAD and other anxiety-related disorders.

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NEUP
Aug 28, 2025
NEUPConferences/Events
▼ -7.2%on this newsshared move

Neuphoria Therapeutics to Present at the H.C. Wainwright 27th Annual Global Investment Conference

Neuphoria Therapeutics Inc. will present at the H.C. Wainwright 27th Annual Global Investment Conference from September 8-10, 2025. CEO Spyros Papapetropoulos will discuss the company's advancements in treatments for neuropsychiatric disorders, including their lead drug candidate BNC-210 for social anxiety disorder and PTSD. The presentation will be available on demand starting September 5.

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NEUP
May 27, 2025
NEUPConferences/Events

Neuphoria to Present at the American Society of Clinical Psychopharmacology (ASCP) 2025 Annual Meeting

Neuphoria Therapeutics Inc. announced its upcoming presentation at the ASCP 2025 Annual Meeting. The company is focused on developing treatments for neuropsychiatric disorders, particularly its lead candidate BNC210 for social anxiety disorder and PTSD. Neuphoria also has a partnership with Merck for early-stage clinical trials targeting cognitive deficits in Alzheimer's disease.

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NEUP
May 20, 2025
NEUPPhases

Neuphoria Provides First Quarter 2025 Business Updates

Neuphoria Therapeutics has reported steady progress in its clinical pipeline for Q1 2025. The company is advancing its lead candidate, BNC210, in a Phase 3 study for Social Anxiety Disorder, with topline data anticipated in Q3. Additionally, its partnered asset MK-1167 is making strides in a Phase 2 trial for Alzheimer's disease.

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NEUP
Apr 15, 2025
NEUPPhases

Neuphoria Provides a Review of 2024 and Highlights 2025 Plans

Neuphoria Therapeutics Inc. reviewed its progress in 2024 and outlined its plans for 2025. The company reported that its BNC210 program for social anxiety disorder has entered Phase 3, while its collaboration with Merck for Alzheimer's treatment has moved to Phase 2. Neuphoria aims to enhance shareholder value by efficiently advancing its pipeline.

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NEUP
Mar 3, 2025
NEUPGeneral
▼ -5.2%on this news

Neuphoria Therapeutics to Ring the Nasdaq Opening Bell on March 3rd, 2025

Neuphoria Therapeutics Inc. will ring the Nasdaq Opening Bell on March 3, 2025, to celebrate its redomiciliation to the US and the launch of the company. CEO Spyros Papapetropoulos emphasized the dedication of the team in positioning Neuphoria for long-term success. The event will be broadcast live from Times Square, New York City.

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NEUP
Feb 12, 2025
NEUPPhases

Neuphoria Therapeutics Inc. to Receive $15M Milestone Payment from Merck

Neuphoria Therapeutics Inc. announced it will receive a $15 million milestone payment from Merck due to the initiation of a Phase 2 clinical trial for MK-1167, aimed at treating Alzheimer's disease symptoms. This payment marks the second milestone achieved in Neuphoria's collaboration with Merck, who has the potential to provide up to $450 million in future milestone payments. Neuphoria's drug pipeline includes various candidates targeting neuropsychiatric disorders, further emphasizing its commitment to developing impactful treatments.

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NEUP
Dec 23, 2024
NEUPGeneral

DESCRIPTION OF CAPITAL STOCK The following description of the capital stock of Neuphoria Therapeutics Inc., a Delaware corporation (the "Company") is a summary only. This summary is subject to the General Corporation Law

Neuphoria Therapeutics Inc. has outlined details regarding its capital stock under Delaware law. The company is authorized to issue a significant number of common and preferred shares and has specific provisions regarding voting rights, dividends, and liquidation rights. Additionally, the certificate of incorporation includes various measures that may hinder stockholder influence over board composition and corporate control, potentially complicating takeover attempts.

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NEUP
Dec 23, 2024
NEUPGeneral

Neuphoria Completes Re-domiciliation and Successor Listing on Nasdaq

Neuphoria Therapeutics Inc. has completed its re-domiciliation from Australia to the United States, establishing itself as the ultimate parent company of Bionomics Limited. Trading of its common stock under the ticker symbol 'NEUP' on the Nasdaq is set to commence on December 24, 2024. Additionally, Neuphoria will issue stock options and warrants to existing holders of Bionomics securities. This strategic move is aimed at enhancing its operations in the US market and advancing its therapeutic candidates.

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NEUP
Dec 16, 2024
NEUPGeneral

Supreme Court of New South Wales approves Bionomics' re-domiciliation Adelaide, Australia and Cambridge, Mass.

Bionomics Limited has received approval from the Supreme Court of New South Wales for its re-domiciliation from Australia to the United States. This change will result in Neuphoria Therapeutics Inc. becoming the ultimate parent company of Bionomics. The implementation date for this Scheme is set for December 23, 2024, with Neuphoria shares poised to trade on Nasdaq under the symbol 'NEUP' starting December 24, 2024. This transition marks a significant shift for the company as it seeks to enhance its operations in the U.S. market.

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About Neuphoria Therapeutics Inc.

Burlington, MA 8 employees neuphoriatx.com
Headquarters100 SUMMIT DR, BURLINGTON, MA, 01803
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