Financials
Cash Data
- Monthly Burn
- Burn Trend
- Dilution Risk
- SEC Filing
Key Stats
Upcoming Catalysts
FDA decisions, readouts and PDUFA dates · scored by probability of approval
NBIX Catalyst Timeline
Dated clinical, regulatory and corporate events for Neurocrine Biosciences, Inc.
Catalyst Timeline
Dated clinical, regulatory & corporate events for Neurocrine Biosciences, Inc.
Upcoming catalysts 2
Event history 50
Past FDA Catalysts and PDUFA Decisions
How NBIX actually traded into and out of each decision
| Date | Drug | Catalyst | Stage | Reaction | Event Move % | Best Trade % |
|---|---|---|---|---|---|---|
| 2026-10-16 | Crinecerfont (CRENESSITY) | Phase 3 data presentation | Phase 3 |
Drug Pipeline Intelligence
| Product | Revenue | Prior period | Change |
|---|---|---|---|
| INGREZZA | |||
| CRENESSITY | |||
| VYKAT XR |
| Drug | Indication | Phase | PTRS | rNPV | Status | Enroll | Velocity | Design | Est. Completion | ML Signal | Last Change |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Osavampator Small moleculeNCT07196501 | Major Depressive Disorder | Phase 3 | RECRUITING | 550 | Jul 1, 2028 | ||||||
| NBI-1117568 Small moleculeNCT07288320 | Bipolar I Disorder | Phase 2 | RECRUITING | 150 | Feb 1, 2028 | ||||||
| NBI-1117567 Small moleculeNCT07832383 | Alzheimer's Disease | Phase 2 | NOT YET_RECRUITING | 135 | Jun 1, 2028 | ||||||
| NBI-1117570 Small moleculeNCT07288333 | Schizophrenia | Phase 2 | RECRUITING | 120 | Aug 1, 2027 | ||||||
| NBI-1065890 Small moleculeNCT07365462 | Tardive Dyskinesia | Phase 2 | RECRUITING | 100 | Mar 1, 2027 | ||||||
| NBIP-01435 Small moleculeNCT07850739 | Congenital Adrenal Hyperplasia | Phase 2 | NOT YET_RECRUITING | 36 | May 11, 2028 | ||||||
| Crinecerfont Small moleculeMarketedNCT07187375 | Congenital Adrenal Hyperplasia | Phase 3 | ACTIVE NOT_RECRUITING | 312 | Oct 4, 2029 | ||||||
| NBI-1065845 Small moleculeNCT05203341 | Major Depressive Disorder | Phase 3 | COMPLETED | 1,633 | Feb 21, 2024 | ||||||
| NBI-1070770 Small moleculeCompletedNCT06267846 | Major Depressive Disorder | Phase 2 | COMPLETED | 73 | Sep 11, 2025 | ||||||
| NBI-1117568 Small moleculeNCT05545111 | Schizophrenia | Phase 3 | COMPLETED | 1,938 | Jul 10, 2024 | ||||||
| VY-AADC01 Monoclonal antibodyCompletedNCT01973543 | Parkinson's Disease | Phase 1 | COMPLETED | 29 | Jan 24, 2020 | ||||||
| NBI-827104 Small moleculeCompletedNCT04625101 | Epileptic Encephalopathy | Phase 2 | COMPLETED | 24 | Oct 11, 2022 | ||||||
| NBI-827104 Small moleculeCompletedNCT04880616 | Essential Tremor | Phase 2 | COMPLETED | 31 | Jun 8, 2022 | ||||||
| Chronocort Small moleculeCompletedNCT03019614 | Congenital Adrenal Hyperplasia | Phase 3 | COMPLETED | 303 | Apr 1, 2010 | ||||||
| Chronocort Small moleculeCompletedNCT05222152 | Primary Adrenal Insufficiency | Phase 2 | COMPLETED | 58 | Oct 18, 2023 | ||||||
| Valbenazine Small moleculeMarketedNCT05110157 | Schizophrenia | Phase 3 | COMPLETED | 442 | Feb 18, 2025 | ||||||
| Valbenazine Small moleculeMarketedNCT04400331 | Chorea, Huntington | Phase 3 | COMPLETED | 289 | Nov 5, 2025 | ||||||
| NBI-98854 Small moleculeMarketedNCT01393600 | Tardive Dyskinesia | Phase 3 | COMPLETED | 659 | Feb 1, 2012 | ||||||
| Valbenazine Small moleculeMarketedNCT02736955 | Tardive Dyskinesia | Phase 3 | COMPLETED | 161 | Jun 30, 2017 | ||||||
| Valbenazine Small moleculeMarketedNCT05206513 | Dyskinesia | Phase 3 | COMPLETED | 86 | Mar 31, 2026 | ||||||
| Crinecerfont Small moleculeMarketedNCT04045145 | CAH - Congenital Adrenal Hyperplasia | Phase 2 | COMPLETED | 8 | Jul 2, 2021 | ||||||
| NBI-74788 Small moleculeMarketedNCT03525886 | CAH - Congenital Adrenal Hyperplasia | Phase 2 | COMPLETED | 18 | Apr 7, 2020 | ||||||
| NBI-98854 Small moleculeMarketedNCT02256475 | Tourette Syndrome | Phase 2 | COMPLETED | 258 | Dec 1, 2015 | ||||||
| Valbenazine Small moleculeMarketedNCT02879578 | Tourette Syndrome | Phase 2 | COMPLETED | 367 | Nov 1, 2017 | ||||||
| NBI-98854 Small moleculeMarketedNCT01916993 | Safety, Tolerability, and PK of NBI-98854 in Hepatically Impaired Subjects | Phase 1 | COMPLETED | 24 | Dec 1, 2013 |
Clinical Trial Results
Readouts, endpoints and source filings for every NBIX program
| Drug Name | Indication | Phase | Date | Trial Results Summary | Title | Source |
|---|---|---|---|---|---|---|
| VYKAT XR | Prader-Willi syndrome | Phase 3 | 2026-06-15 | 6.2 points at Year 1; 6.5 points at Year 2; 6.2 points at Year 3; -2.5 in anxiety; -2.4 in rigidity/irritability; -2.3 in compulsivity; -2.1 in aggressive behaviors; -1.5 in disordered thinking; -1.1 in depressionRead More | Soleno Therapeutics Presents New VYKAT® XR (diazoxide choline) Data at ENDO 2026 Demonstrating Meaningful and Durable Improvements in Hyperphagia and Behavioral Symptoms in Prader-Willi Syndrome Following Randomized Withdrawal Period Soleno Therapeutics, a Neurocrine Biosciences (Nasdaq: NBIX) company, today announced late-breaking data at ENDO 2026 showing that resuming treatment ...Read More |
Inside Trades
| Insider | Side | Shares | Price | Value | Date |
|---|---|---|---|---|---|
| Boyer David W.Officer (Chief Corp. Affairs Officer) | Sell | -826 8,722 held | $157.45 | 09/14/2026 |
Hedge Fund 13F Activity
Hedge Funds invested in NBIX
| Fund | % of Portfolio | Current MV | Shares Owned | Activity |
|---|---|---|---|---|
| RTW INVESTMENTS, LP | 1.8 % (28.6 %) | 213.69 M | 1.27 M | 19.38% ( 205.85 K) |
NBIX Institutional Ownership Trends
NBIX Short Interest
Shares sold short, counted twice a month.
Options Data
Option Volume
Option Chain Statistics
| Expiry | Call Vol | Put Vol | Vol P/C | Call OI | Put OI | OI P/C | IV Call | IV Call OI-Wtd | IV Call Vol-Wtd | IV Put | IV Put OI-Wtd | IV Put Vol-Wtd |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-11-20 | ||||||||||||
Real-Time Option Chain
| Calls | Strike | Puts | ||||
|---|---|---|---|---|---|---|
| Last | Vol | OI | Last | Vol | OI | |
| No data available | ||||||
Calls vs Puts by Expiry
Competitive positioning
How NBIX ranks across every disease it competes in
NBIX News
Neurocrine Biosciences Presents New Analysis Establishing Benchmark for Clinically Meaningful Change in Overall Health Reported by Patients with Tardive Dyskinesia
Neurocrine Biosciences announced a new analysis establishing a 6-point increase on the EQ Visual Analogue Scale as a benchmark for clinically meaningful change in patients with tardive dyskinesia treated with INGREZZA. This finding contextualizes a mean 13.1-point improvement observed in the KINECT-PRO study. The results will be presented at the Academy of Managed Care Pharmacy Nexus 2026 conference.
Read more →Neurocrine Biosciences Announces Publication in Orphanet Journal of Rare Diseases Advancing Understanding of Hyperphagia in Prader-Willi Syndrome
Neurocrine Biosciences announced a publication in the Orphanet Journal of Rare Diseases, detailing expert insights on hyperphagia in Prader-Willi syndrome (PWS). The manuscript emphasizes the complexity of hyperphagia and the importance of integrated care management. VYKAT XR, an FDA-approved treatment, is noted as a significant advancement in managing this condition.
Read more →Neurocrine Biosciences Initiates Phase 2 Clinical Study Evaluating NBI-'567 in Adults with Alzheimer's Disease
Neurocrine Biosciences has launched a Phase 2 clinical study for NBI-'567, an investigational drug aimed at treating cognitive impairment in adults with mild to moderate Alzheimer's disease. The study will assess the drug's efficacy, safety, and pharmacokinetics over a 12-week period. This initiative reflects Neurocrine's commitment to developing innovative treatments for Alzheimer's and other neurological conditions.
Read more →Neurocrine Biosciences Presents Real-World Evidence Mapping the Lifelong, Evolving Impact of Classic Congenital Adrenal Hyperplasia
Neurocrine Biosciences presented new real-world data on classic congenital adrenal hyperplasia (CAH) at the Endocrine Nurses Society Annual Symposium 2026. The analysis utilized patient records to illustrate the diverse challenges faced by CAH patients throughout their lives. It emphasized the importance of understanding patient experiences to enhance care and support strategies.
Read more →Neurocrine Biosciences Announces Conference Call and Webcast of Third Quarter 2026 Financial Results
Neurocrine Biosciences has announced a conference call and webcast for its third quarter 2026 financial results, scheduled for November 2, 2026. The press release will precede the call, providing financial insights to investors. The company continues to focus on developing treatments for various neurological and psychiatric disorders, showcasing its commitment to patient care.
Read more →Neurocrine Biosciences to Present Research Advancing Understanding of Prader-Willi Syndrome and Real-World Experience with VYKAT® XR (diazoxide choline) at Foundation for Prader-Willi Research Symposium & Family Conference
Neurocrine Biosciences will present research on Prader-Willi syndrome and VYKAT XR at the FPWR 2026 Annual Research Symposium. The studies include the PWS-VISTA observational study, which focuses on real-world evidence of VYKAT XR, and the BRAVE-PWS study, which captures caregiver experiences. The findings aim to deepen understanding of PWS and improve treatment approaches.
Read more →Neurocrine Biosciences Appoints Eiry W. Roberts, M.D., as Chief Medical Officer
Neurocrine Biosciences has appointed Eiry W. Roberts, M.D., as Chief Medical Officer, effective immediately. Dr. Roberts previously held this role from 2018 to 2025 and has been a Strategic Advisor since. Her return is expected to provide continuity as the company advances its late-stage clinical programs and prepares for significant milestones.
Read more →Neurocrine Biosciences to Present at Upcoming Investor Conferences in September
Neurocrine Biosciences, Inc. announced its participation in several investor conferences in September 2026. The events include the Wells Fargo 21st Annual Healthcare Conference, Cantor Global Healthcare Conference 2026, and Morgan Stanley 24th Annual Global Healthcare Conference. Executives will engage in fireside chats, and webcasts will be available for those unable to attend live.
Read more →Nxera Pharma’s Partner Neurocrine Biosciences Receives IND Acceptance from the FDA for Phase 2 Study of NBI-1117567 for Alzheimer's Cognition
Neurocrine Biosciences has received IND acceptance from the FDA for NBI-1117567, an investigational drug for Alzheimer's cognition. Nxera Pharma will receive a $10 million milestone payment as part of their collaboration. NBI-1117567 is the third compound from Nxera's muscarinic agonist portfolio to advance to Phase 2, indicating progress in addressing Alzheimer's disease.
Read more →Neurocrine Biosciences Announces Publication of KINECT-PRO™ Findings Demonstrating INGREZZA® (valbenazine) Capsules Improved Patient-Reported Quality of Life and Daily Functioning for People Living with Tardive Dyskinesia
Neurocrine Biosciences announced the publication of KINECT-PRO™ findings, showing that INGREZZA® (valbenazine) significantly improves patient-reported quality of life and functionality in individuals with tardive dyskinesia (TD). The Phase 4 study revealed that 58% of participants achieved symptomatic remission by Week 24, with improvements noted across various severity levels. The results underscore the treatment's effectiveness in enhancing daily functioning and reducing movement severity.
Read more →Neurocrine Biosciences Announces Initiation of Phase 1 Clinical Study Evaluating NBIP-'1968, a GLP-1/GIP/Glucagon Receptor Triple Agonist
Neurocrine Biosciences has initiated a Phase 1 clinical study for NBIP-'1968, a triple agonist targeting GLP-1, GIP, and glucagon receptors, aimed at treating obesity. This study will assess the safety and tolerability of the drug in adult participants with varying body mass indices. The development of NBIP-'1968 is part of a broader strategy to expand Neurocrine's obesity treatment options.
Read more →Neurocrine Biosciences Reports Second-Quarter 2026 Financial Results
Neurocrine Biosciences reported a strong second-quarter performance for 2026, with total revenues increasing by 39% year-over-year to $959 million. The company raised its net sales guidance for INGREZZA, reflecting robust demand and prescription growth. Additionally, the acquisition of Soleno Therapeutics is expected to strengthen its position in the market. Positive clinical trial results for CRENESSITY further bolster the company's outlook.
Read more →Neurocrine Biosciences Announces Key Leadership Hiring, Promotions
Neurocrine Biosciences has announced the appointment of three Senior Vice Presidents to enhance its leadership as it enters a new growth phase. Bret Paulson, David Bradfute, and Aaron Vosburgh will take on key roles in market access, intellectual property, and finance, respectively. These changes aim to support the company's expanding commercial portfolio and neuroscience pipeline.
Read more →Neurocrine Biosciences Appoints Samir Siddhanti Chief Business Officer
Neurocrine Biosciences has appointed Samir Siddhanti as Chief Business Officer, where he will lead the company's growth strategy and oversee business development. Siddhanti has been with Neurocrine since 2017, playing a key role in strategic partnerships and the recent acquisition of Soleno Therapeutics. His leadership is expected to enhance the company's pipeline and drive future growth.
Read more →Neurocrine Biosciences Announces Conference Call and Webcast of Second Quarter 2026 Financial Results
Neurocrine Biosciences has announced a conference call and webcast to discuss its second quarter 2026 financial results. Scheduled for July 30, 2026, the call will begin at 1:30 p.m. PT. The company aims to provide updates on its financial performance and ongoing projects, showcasing its commitment to addressing neurological and psychiatric disorders.
Read more →Neurocrine Biosciences Initiates Phase 2 Study of Crinecerfont in Pediatric Patients Under 4 Years Old with Classic Congenital Adrenal Hyperplasia
Neurocrine Biosciences has launched a Phase 2 clinical trial for crinecerfont, targeting children under 4 years with classic congenital adrenal hyperplasia (CAH). The study aims to evaluate the drug's safety and tolerability in a vulnerable population often reliant on high glucocorticoid doses. This initiative reflects the company's commitment to improving treatment options for young patients with CAH.
Read more →Neurocrine Biosciences Presents First Retrospective Case Series of CRENESSITY® (crinecerfont) in Patients with Classic Congenital Adrenal Hyperplasia Due to 11β‑Hydroxylase Deficiency at ENDO 2026
Neurocrine Biosciences presented a retrospective case series at ENDO 2026, showcasing the effects of CRENESSITY (crinecerfont) in patients with classic congenital adrenal hyperplasia due to 11β-hydroxylase deficiency. The study revealed substantial reductions in adrenal hormone levels and glucocorticoid doses among patients. This case series provides preliminary insights into the treatment of this rare condition, emphasizing the need for further research.
Read more →Neurocrine Biosciences Presents New Two-Year CRENESSITY® (crinecerfont) Data Demonstrating Improved Growth Measures in Pediatric Patients with Classic Congenital Adrenal Hyperplasia at ENDO 2026
Neurocrine Biosciences presented two-year data on CRENESSITY (crinecerfont) at ENDO 2026, showing positive growth outcomes in pediatric patients with classic congenital adrenal hyperplasia (CAH). The study indicated slowed bone age progression and improved predicted adult height. Caregiver surveys revealed universal satisfaction and optimism regarding the treatment's impact on children's quality of life.
Read more →Neurocrine Biosciences Presents New Two-Year CRENESSITY® (crinecerfont) Data Demonstrating Improvements in Cardiometabolic Outcomes in Adults with Classic Congenital Adrenal Hyperplasia at ENDO 2026
Neurocrine Biosciences presented new data from the Phase 3 CAHtalyst Adult study at ENDO 2026, showing that CRENESSITY (crinecerfont) significantly improved cardiometabolic outcomes and reduced glucocorticoid doses in adults with classic congenital adrenal hyperplasia (CAH). Over two years, participants experienced weight loss, improved insulin resistance, and enhanced bone health. Patient surveys indicated high satisfaction and improved quality of life.
Read more →Soleno Therapeutics Presents New VYKAT® XR (diazoxide choline) Data at ENDO 2026 Demonstrating Meaningful and Durable Improvements in Hyperphagia and Behavioral Symptoms in Prader-Willi Syndrome Following Randomized Withdrawal Period
Soleno Therapeutics presented data showing VYKAT XR improved hyperphagia and behavioral symptoms in Prader-Willi syndrome patients after a withdrawal period. Participants who resumed treatment demonstrated durable benefits continuing through two years. The drug also showed sustained improvements compared to natural history data for up to three years. These results reinforce the long-term efficacy of the therapy for this condition.
Read more →