Recent Updates
Recently added Catalysts

taranabant

Phase 2

Obesity and Obesity-related Medical Conditions | Small molecule | Metabolic |Merck & Company, Inc.|Last Updated: Jun 7, 2016

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment500

FDA Designations

No designations recorded

Clinical trial landscape

taranabant · 2 trials · 2 indications

Phase 2 2
NCT00131430An Eighteen Month Efficacy and Safety Study in Obese Patients (0364-020)(COMPLETED)Obesity and Obesity-related Medical Conditions
COMPLETED500 Analytics
NCT00109135A Study to Investigate a Research Drug as an Aid for Smoking Cessation in Chronic Cigarette Smokers (0364-007)Smoking
COMPLETED300 Analytics
PHASE2COMPLETED
An Eighteen Month Efficacy and Safety Study in Obese Patients (0364-020)(COMPLETED)
Obesity and Obesity-related Medical ConditionsUnlock trial analytics
PHASE2COMPLETED
A Study to Investigate a Research Drug as an Aid for Smoking Cessation in Chronic Cigarette Smokers (0364-007)
SmokingUnlock trial analytics

Study Endpoints

Primary Endpoints

After 24 weeks, body weight, safety, and tolerability
After 24 weeks
Quitting smoking after 8 weeks of treatment by measuring lab values and expired breath CO levels
after 8 weeks of treatment

Secondary Endpoints

After 80 weeks, body weight
After 80 weeks
Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
taranabantDRUG -
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo

Inclusion Criteria: * Obese patients with a body mass index between 30kg/m2 and 43 kg/m2, inclusive (BMI between 27 kg/m2 and 43kg/m2, inclusive for those with obesity-related comorbidities including hypertension, dyslipidemia and sleep apnea). Exclusion Criteria: * Patients with serious or unsta...

Unlock Eligibility Criteria

Frequently asked questions about taranabant

What is taranabant used for?

Taranabant is an investigational small molecule being studied for smoking cessation and for obesity and obesity-related medical conditions. It is in Phase 2 clinical development by Merck & Company, Inc. (MRK).

Who makes taranabant?

Taranabant is being developed by Merck & Company, Inc., which trades on the New York Stock Exchange under the ticker MRK. The drug is currently in Phase 2 clinical trials for smoking and obesity-related conditions.

What phase is taranabant in?

Taranabant is in Phase 2 clinical development. It is an investigational drug and has not been approved by the FDA. Two Phase 2 trials have been completed, one in smoking and one in obesity.

What clinical trials is taranabant in?

Taranabant has been studied in two completed Phase 2 trials. NCT00109135 investigated the drug as an aid for smoking cessation in 300 chronic cigarette smokers. NCT00131430 was an 18-month efficacy and safety study in 500 obese patients with obesity-related medical conditions.

Is taranabant the same as any other drug?

Taranabant is a distinct investigational compound developed by Merck. It is not known by any other names in the clinical trial data. It is being studied separately for smoking cessation and for obesity.