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V205C, measles, mumps, and rubella virus vaccine live

Phase 2

Measles | Vaccine | Infectious Disease |Merck & Company, Inc.|Last Updated: Mar 15, 2017

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment1,100

FDA Designations

No designations recorded

Clinical trial landscape

V205C, measles, mumps, and rubella virus vaccine live · 1 trial · 1 indication

Phase 2 1
NCT00109278A Measles, Mumps, and Rubella Investigational Vaccine Trial (V205C-010)(COMPLETED)Measles
COMPLETED1,100 Analytics
PHASE2COMPLETED
A Measles, Mumps, and Rubella Investigational Vaccine Trial (V205C-010)(COMPLETED)
MeaslesUnlock trial analytics

Study Endpoints

Primary Endpoints

Antibody response rate to measles at 6 weeks postvaccination

Secondary Endpoints

Geometric mean titers to measles by ELISA at 6 weeks postvaccination
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposePREVENTION

Interventions

NameTypeDescription
V205C, measles, mumps, and rubella virus vaccine liveBIOLOGICAL -
Comparator: Measles, Mumps, and Rubella Virus Vaccine LiveBIOLOGICAL -
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Eligibility Criteria

Age Range12 Months to 18 Months
SexALL
Healthy VolunteersYes

Inclusion Criteria: * Healthy children 12 to 18 months of age. Exclusion Criteria: * Previous receipt of measles, mumps, rubella and/or varicella vaccine. * Prior infection or exposure to (within last 4 weeks) measles, mumps, rubella, varicella and/or zoster. * Any medical condition that might in...

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Frequently asked questions about V205C, measles, mumps, and rubella virus vaccine live

What is V205C, measles, mumps, and rubella virus vaccine live?

V205C is an investigational live vaccine developed by Merck & Company, Inc. (MRK) that targets measles, mumps, and rubella. It is being studied for the prevention of measles and is designed to prompt an immune response against these viruses. The vaccine is in Phase 2 clinical development.

What is V205C used for in measles?

V205C is being developed for the prevention of measles as part of a combined measles, mumps, and rubella vaccine. It is intended to protect against measles virus infection through active immunization. The asset is investigational and has been evaluated in a Phase 2 trial in healthy volunteers.

Who makes V205C?

V205C is developed by Merck & Company, Inc., which trades on the New York Stock Exchange under the ticker MRK. Merck is the sponsor of the clinical program evaluating this investigational measles, mumps, and rubella vaccine candidate.

What phase is V205C in?

V205C is in Phase 2 clinical development. It is an investigational vaccine and has not been approved by the FDA. The Phase 2 program has been completed, with one completed trial and no active trials currently listed for this asset.

What clinical trials is V205C in?

V205C has been evaluated in one completed Phase 2 trial, NCT00109278, titled A Measles, Mumps, and Rubella Investigational Vaccine Trial (V205C-010). The randomized, double-blind study enrolled 1,100 participants aged 12 months and older, including healthy volunteers, and has been completed.