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Tulisokibart Form 1

Phase 1

Healthy | Monoclonal antibody | Other |Merck & Company, Inc.|Last Updated: Jun 10, 2026

Success Probability

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Market & Valuation

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Trial Design

RandomizedCONTROLLED
Total Trials1
Total Enrollment330

FDA Designations

No designations recorded

Clinical trial landscape

Tulisokibart Form 1 · 1 trial · 1 indication

Phase 1 1
NCT07405177A Study of MK-7240 in Healthy Participants (MK-7240-009)Healthy
ACTIVE NOT_RECRUITING330 Analytics
PHASE1ACTIVE NOT_RECRUITING
A Study of MK-7240 in Healthy Participants (MK-7240-009)
HealthyUnlock trial analytics

Study Endpoints

Primary Endpoints

Area Under the Concentration-Time Curve from Time 0 to Infinity (AUC0-Inf) of Tulisokibart
At designated timepoints up to 14 weeks

Blood samples will be collected to determine the AUC0-inf of tulisokibart.

Area Under the Concentration-Time Curve from Time 0 to Last (AUC0-Last) of Tulisokibart
At designated timepoints up to 14 weeks

Blood samples will be collected to determine the AUC0-last of tulisokibart.

Maximum Plasma Concentration (Cmax) of Tulisokibart
At designated timepoints up to 14 weeks

Blood samples will be collected to determine the Cmax of tulisokibart.

Secondary Endpoints

Number of Participants Who Experience an Adverse Event (AE)
At designated timepoints up to 14 weeks
Number of Participants Who Discontinue Study Due to an AE
At designated timepoints up to 14 weeks
Time to Maximum Plasma Concentration (Tmax) of Tulisokibart
At designated timepoints up to 14 weeks
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeBASIC_SCIENCE

Treatment Arms

ArmTypeDescription
Arm 1: Tulisokibart Form 1EXPERIMENTALParticipants will receive tulisokibart form 1.
Arm 2: Tulisokibart Form 2EXPERIMENTALParticipants will receive tulisokibart form 2.

Interventions

NameTypeDescription
Tulisokibart Form 1BIOLOGICALSolution for injection.
Tulisokibart Form 2BIOLOGICALSolution for injection.
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Eligibility Criteria

Age Range18 Years to 55 Years
SexALL
Healthy VolunteersYes
Study Sites2

Inclusion Criteria The main inclusion criteria include but are not limited to the following: * Has a body-mass index (BMI) between 18 and 32 kg/m\^2 Exclusion Criteria The main exclusion criteria include but are not limited to the following: * Has a history of more than 1 episode of herpes zost...

Countries:Australia
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Recent Changes (Last 90 Days)

MEDIUMJun 10, 2026NCT07405177Status: RECRUITING → ACTIVE_NOT_RECRUITING
MEDIUMJun 10, 2026NCT07405177Status: RECRUITING → ACTIVE_NOT_RECRUITING

Frequently asked questions about Tulisokibart Form 1

What is Tulisokibart Form 1 used for?

Tulisokibart Form 1 is an investigational monoclonal antibody being studied in healthy participants. It is currently in Phase 1 clinical development, and the ongoing trial is evaluating its safety and tolerability in healthy volunteers. It is not approved for any indication and remains in early-stage clinical testing.

Who makes Tulisokibart Form 1?

Tulisokibart Form 1 is being developed by Merck & Company, Inc., which trades under the ticker symbol MRK. The company is conducting a Phase 1 clinical trial of this investigational monoclonal antibody in healthy participants.

What phase is Tulisokibart Form 1 in?

Tulisokibart Form 1 is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. The ongoing Phase 1 trial is active but not recruiting participants, and it is studying the drug in healthy volunteers.

What clinical trials is Tulisokibart Form 1 in?

Tulisokibart Form 1 is being studied in one active Phase 1 clinical trial with the identifier NCT07405177. The trial, titled 'A Study of MK-7240 in Healthy Participants (MK-7240-009)', is enrolling 330 healthy participants in Australia and is currently active but not recruiting.

Is Tulisokibart Form 1 the same as MK-7240?

Yes, Tulisokibart Form 1 is also known as MK-7240. The ongoing Phase 1 clinical trial NCT07405177 is titled 'A Study of MK-7240 in Healthy Participants', confirming that MK-7240 is the alternative name for this investigational monoclonal antibody.