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TR701 FA

Phase 2

Major Cutaneous Abscess | Small molecule | Other |Merck & Company, Inc.|Last Updated: Aug 29, 2018

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment200
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT01519778A Phase 2 Safety and Exploratory Skin Lesion Measurement of TR-701 FA StudyPHASE2 COMPLETED 200Feb 15, 2012Aug 27, 2012Aug 29, 201810 United States
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Study Endpoints
Primary Endpoints
Incidence of Adverse Events (AEs) and Serious Adverse Events (SAEs)
24-31 days

Safety will be assessed through summaries of the incidence of AEs and SAEs as well as through summaries of vital signs, physical examinations, ECG findings, and laboratory assessments (hematology, serum chemistry, and urinalysis).

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Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeOTHER
Treatment Arms
ArmTypeDescription
TR-701 FAEXPERIMENTAL -
Interventions
NameTypeDescription
TR701 FADRUG1 tablet 200 mg once daily
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites10

Inclusion Criteria: * Male or female patients ≥ 18 years of age * Suspected or documented gram-positive infection from baseline Gram stain or culture. * Cellulitis/erysipelas or major cutaneous abscesses at Screening Exclusion Criteria: * Postsurgical or open wound infections * Severe sepsis or s...

Countries:United States
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