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MK2295

Phase 2

Pain, Postoperative | Small molecule | Pain |Merck & Company, Inc.|Last Updated: Nov 2, 2015

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment89

FDA Designations

No designations recorded

Clinical trial landscape

MK2295 · 1 trial · 2 indications

Phase 2 1
NCT00387140A Study to Evaluate the Safety and Efficacy of an Investigational Drug in the Treatment of Postoperative Dental Pain (MK-2295-005)Pain, Postoperative
COMPLETED89 Analytics
PHASE2COMPLETED
A Study to Evaluate the Safety and Efficacy of an Investigational Drug in the Treatment of Postoperative Dental Pain (MK-2295-005)
Pain, PostoperativeUnlock trial analytics

Study Endpoints

Primary Endpoints

Peak analgesic response, safety, and tolerability
Over 24 Hours

Secondary Endpoints

Onset of analgesia, duration of analgesia
Over 24 Hours
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
MK2295DRUG -
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Eligibility Criteria

Age Range18 Years to 45 Years
SexMALE
Healthy VolunteersYes

Inclusion Criteria: * Patients in generally good health who are scheduled to have two or more third molars removed, at least one of which is partially or completely embedded in bone and is a mandibular impaction Exclusion Criteria: * Patient has a temperature of 37.5C or greater prior to dosing *...

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Frequently asked questions about MK2295

What is MK2295 used for?

MK2295 is an investigational small molecule being studied for the treatment of postoperative pain, specifically pain following tooth extraction. It was evaluated in a Phase 2 clinical trial for this indication. The drug is not approved and remains in clinical development.

Who makes MK2295?

MK2295 is being developed by Merck & Company, Inc., a pharmaceutical company traded on the New York Stock Exchange under the ticker symbol MRK. The company sponsored the clinical trial of this investigational drug for postoperative dental pain.

What phase is MK2295 in?

MK2295 is in Phase 2 clinical development. A Phase 2 trial evaluating the drug for postoperative dental pain has been completed. The drug is investigational and has not received regulatory approval for any use.

What clinical trials is MK2295 in?

MK2295 has been studied in one completed Phase 2 clinical trial, registered as NCT00387140. This trial evaluated the safety and efficacy of the drug in 89 participants with postoperative dental pain following tooth extraction. The study was randomized and double-blind.

Is MK2295 the same as any other drug?

No alternative names for MK2295 have been identified. The drug is referred to solely as MK2295 in the available clinical trial information. It is an investigational small molecule being developed by Merck & Company, Inc.