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MK0991, caspofungin

Phase 2

Aspergillosis | Small molecule | Infectious Disease |Merck & Company, Inc.|Last Updated: Jan 13, 2015

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment55

FDA Designations

No designations recorded

Clinical trial landscape

MK0991, caspofungin · 1 trial · 1 indication

Phase 2 1
NCT00076869MK0991 in Combination With Standard Antifungal Agent(s) for the Treatment of Salvage Invasive Aspergillosis (0991-037)Aspergillosis
COMPLETED55 Analytics
PHASE2COMPLETED
MK0991 in Combination With Standard Antifungal Agent(s) for the Treatment of Salvage Invasive Aspergillosis (0991-037)
AspergillosisUnlock trial analytics

Study Endpoints

Primary Endpoints

Tolerability.

Secondary Endpoints

Clinical response
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
MK0991, caspofungin acetateDRUG -
Comparator: amphotericin BDRUG -
Comparator: lipid formulation of amphotericin B and/or azoleDRUG -
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Eligibility Criteria

Age Range16 Years to N/A
SexALL
Healthy VolunteersNo

* Patients must meet a specific definition of probable or definite invasive aspergillosis and be considered to have failed or be intolerant of standard antifungal therapy. * The patient must be at least 16 years old and if a woman of childbearing potential, must have a negative serum or urine pregna...

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Frequently asked questions about MK0991, caspofungin

What is MK0991 used for?

MK0991 is an investigational small molecule being studied for the treatment of aspergillosis, a fungal infection. It is currently in Phase 2 clinical development and has been evaluated in combination with standard antifungal agents for salvage therapy of invasive aspergillosis.

Who is developing MK0991?

MK0991 is being developed by Merck & Company, Inc., which trades on the New York Stock Exchange under the ticker symbol MRK. The company is conducting clinical trials to evaluate the drug's safety and efficacy in patients with aspergillosis.

What phase is MK0991 in?

MK0991 is in Phase 2 clinical development for aspergillosis. It is an investigational drug, meaning it has not yet been approved by regulatory authorities and is still undergoing clinical evaluation to determine its safety and effectiveness.

What clinical trials is MK0991 in?

MK0991 has been studied in a completed Phase 2 clinical trial with the identifier NCT00076869. This trial evaluated MK0991 in combination with standard antifungal agents for the treatment of salvage invasive aspergillosis and enrolled 55 participants aged 16 years and older.

Is MK0991 the same as caspofungin?

Yes, MK0991 is also known as caspofungin. Both names refer to the same investigational drug being developed by Merck & Company, Inc. for the treatment of aspergillosis. The drug is currently in Phase 2 clinical trials.