Recent Updates
Recently added Catalysts

MK0731

Phase 1

Cancer | Small molecule | Oncology |Merck & Company, Inc.|Last Updated: Jan 30, 2015

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment30

FDA Designations

No designations recorded

Clinical trial landscape

MK0731 · 1 trial · 1 indication

Phase 1 1
NCT00104364A Study of MK0731 in Patients With Advanced Solid Tumors (0731-002)(COMPLETED)Cancer
COMPLETED30 Analytics
PHASE1COMPLETED
A Study of MK0731 in Patients With Advanced Solid Tumors (0731-002)(COMPLETED)
CancerUnlock trial analytics

Study Endpoints

Primary Endpoints

Safety and tolerability of MK0731 administered as a 24-hour CIV Infusion. Dose limiting toxicities. Maximum tolerated dose and recommended Phase II dose of L-001154704 administered as a 24 hour CIV infusion.

Secondary Endpoints

Predose predictive biomarkers of response to MK0731
Unlock Study Endpoints

Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
MK0731DRUG -
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo

Inclusion Criteria: * Patients who are at least 18 years of age with recurrent or non-responsive solid tumors, or cancers for whom standard therapy does not exist. Part of the study includes only patients who have taxane-resistant cancers. Exclusion Criteria: * Patients who have had treatment wit...

Unlock Eligibility Criteria

Frequently asked questions about MK0731

What is MK0731 used for?

MK0731 is an investigational small molecule being studied for the treatment of cancer. It is in Phase 1 clinical development, with a completed trial in patients with advanced solid tumors. The drug is not approved and remains under investigation for its safety and efficacy in oncology.

Who makes MK0731?

MK0731 is being developed by Merck & Company, Inc., a pharmaceutical company traded on the New York Stock Exchange under the ticker symbol MRK. The company is conducting clinical research to evaluate the drug's potential in treating cancer.

What phase is MK0731 in?

MK0731 is in Phase 1 clinical development. A Phase 1 study of the drug in patients with advanced solid tumors has been completed. The drug is investigational and has not been approved by regulatory authorities for any use.

What clinical trials is MK0731 in?

MK0731 has one completed clinical trial, identified as NCT00104364, titled 'A Study of MK0731 in Patients With Advanced Solid Tumors (0731-002)(COMPLETED)'. This Phase 1 study enrolled 30 participants with cancer, with a minimum age of 18 years.

Is MK0731 FDA approved?

MK0731 is not FDA approved. It is an investigational drug currently in Phase 1 clinical development. A completed trial has evaluated its use in advanced solid tumors, but the drug has not received regulatory approval for any indication.