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imiquimod

Phase 3

Actinic Keratoses | Small molecule | Dermatology |3M Company|Last Updated: May 9, 2006

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment20

FDA Designations

No designations recorded

Clinical trial landscape

imiquimod · 1 trial · 1 indication

Phase 3 1
NCT00175643Safety and Efficacy of Imiquimod Applied in Dose-Cycle for Actinic KeratosesActinic Keratoses
COMPLETED20 Analytics
PHASE3COMPLETED
Safety and Efficacy of Imiquimod Applied in Dose-Cycle for Actinic Keratoses
Actinic KeratosesUnlock trial analytics

Study Endpoints

Primary Endpoints

Complete clearance rate - defined as the proportion of subjects at the end of cycle 1 or cycle 2 with no (zero) clinically visible AK lesions in the treatment area.

Secondary Endpoints

Partial clearance rate - defined as the proportion of subjects at the end of cycle 2 with at least 75% reduction from the number of AK lesions counted at baseline in the treatment area
Sustained clearance rate at week 8 post-treatment.
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
imiquimodDRUG -
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Eligibility Criteria

Age Range18 Years to 75 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * At least 18 years of age. * Have a total of 4 to 8 clinically typical, discrete, non-hyperkeratotic, non-hypertrophic AK lesions located within a contiguous 25 cm2 treatment area (balding scalp or face, but not both). * Free of any significant findings (e.g. tattoos) in the po...

Countries:Canada
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Frequently asked questions about imiquimod

What is imiquimod used for?

Imiquimod is a small molecule being studied for the treatment of actinic keratoses, a skin condition caused by sun damage. It is in Phase 3 clinical development and is being developed by 3M Company (NYSE: MMM).

What does imiquimod target?

Imiquimod is a small molecule immunomodulator. It works by stimulating the immune system to fight abnormal skin cells. The specific molecular target has not been disclosed in the available information.

Who makes imiquimod?

Imiquimod is being developed by 3M Company, which trades on the New York Stock Exchange under the ticker symbol MMM. The company is conducting clinical trials to evaluate the drug for actinic keratoses.

What phase is imiquimod in?

Imiquimod is in Phase 3 clinical development for actinic keratoses. It is an investigational drug and has not been approved by regulatory authorities. One Phase 3 trial has been completed.

What clinical trials is imiquimod in?

Imiquimod has one completed Phase 3 trial, NCT00175643, which evaluated the safety and efficacy of the drug applied in a dose-cycle for actinic keratoses. The trial enrolled 20 participants in Canada and was not randomized or blinded.

Is imiquimod the same as Aldara?

Imiquimod is the generic name for the drug also known as Aldara. The information provided does not specify alternative names, so it is not confirmed whether imiquimod is the same as Aldara.