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Arterial line, Motion

Phase 3

Healthy | Unknown | Respiratory |Medtronic plc.|Last Updated: May 5, 2017

Success Probability

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Market & Valuation

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Trial Design

CONTROLLED
Total Trials1
Total Enrollment18

FDA Designations

No designations recorded

Clinical trial landscape

Arterial line, Motion · 1 trial · 2 indications

Phase 3 1
NCT02247765Controlled Acute Hypoxia Study Comparing Pulse Oximetry to Arterial Blood Samples During MotionHealthy
COMPLETED18 Analytics
PHASE3COMPLETED
Controlled Acute Hypoxia Study Comparing Pulse Oximetry to Arterial Blood Samples During Motion
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Study Endpoints

Primary Endpoints

SpO2 Accuracy During Motion Conditions - MaxA Sensor
up to 6 months

For each range specified, SpO2 accuracy of the pulse oximeter equipment is stated in terms of the Accuracy Root-Mean-Square (ARMS) difference between measured values (SpO2) and reference blood values (SaO2). The MaxA sensors has a different bandage from the MaxN sensor, and therefore a different form and fit.

SpO2 Accuracy During Motion Conditions - MaxN Sensor
up to 6 months

For each range specified, SpO2 accuracy of the pulse oximeter equipment is stated in terms of the Accuracy Root-Mean-Square (ARMS) difference between measured values (SpO2) and reference blood values (SaO2). The MaxN sensor has a different bandage from the MaxA sensor, and therefore a different form and fit.

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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeBASIC_SCIENCE

Treatment Arms

ArmTypeDescription
Arterial LineEXPERIMENTALCO-Oximetry value obtained as a comparator. Obtained during motion conditions.
MotionEXPERIMENTALThe subject has to perform motions during the procedure. This is to verify that device is able to read through motion.

Interventions

NameTypeDescription
Arterial lineDEVICEArterial line is inserted to draw a CO-Oximeter value as it is the gold standard and as advised in ISO 80601
MotionDEVICEThe subject is asked to move their hand by either rubbing or tapping their fingers at a specified frequency and amplitude during portions of the hypoxic procedure.
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Eligibility Criteria

Age Range18 Years to 50 Years
SexALL
Healthy VolunteersYes
Study Sites2

Inclusion Criteria: * Male or female of any race * 18-50 years old, inclusive * Females: negative urine pregnancy test on the day of study participation (prior to exposure to hypoxia) * Completed within the last year: physical exam by a licensed physician, physician assistant (PA), or advanced prac...

Countries:United States
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Frequently asked questions about Arterial line, Motion

What is Arterial line, Motion used for?

Arterial line, Motion is a device being studied for use in healthy individuals under controlled hypoxia, or low oxygen conditions. It is being evaluated in a clinical trial that compares pulse oximetry readings to arterial blood samples during motion. The study is in Phase 3 and is being developed by Medtronic plc.

Who makes Arterial line, Motion?

Medtronic plc, traded under the ticker MDT, is the developer of Arterial line, Motion. The company is conducting a Phase 3 clinical trial for this device, which is being studied in healthy volunteers under hypoxic conditions. The trial is completed and took place in the United States.

What phase is Arterial line, Motion in?

Arterial line, Motion is in Phase 3 clinical development. It is an investigational device and has not been approved. The Phase 3 trial, which is completed, enrolled 18 healthy participants and was conducted in the United States. The study was controlled but not randomized or double-blinded.

What clinical trials is Arterial line, Motion in?

Arterial line, Motion has one completed Phase 3 clinical trial, identified as NCT02247765. The trial, titled 'Controlled Acute Hypoxia Study Comparing Pulse Oximetry to Arterial Blood Samples During Motion,' enrolled 18 healthy adults in the United States. The study was controlled and included conditions of healthy and hypoxia.

Is Arterial line, Motion FDA approved?

Arterial line, Motion is not FDA approved. It is an investigational device currently in Phase 3 clinical development. The completed trial, NCT02247765, studied the device in healthy volunteers under hypoxic conditions, but approval status has not been established. Medtronic plc is the developer.