Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
CHG · 3 trials · 2 indications
Change was calculated as the baseline time point minus the later time points over an 8 hour period.
Evaluate the Log Reduction of normal flora at various timepoints.
Evaluate the Log Reduction of Normal Flora at various sites and timepoints
| Arm | Type | Description |
|---|---|---|
| CHG Cloth | EXPERIMENTAL | 3 min application time |
| Comparator CHG | ACTIVE_COMPARATOR | Marketed 2% CHG |
| CHG 1 min | EXPERIMENTAL | 1 min application time |
| CHG 2 min | EXPERIMENTAL | 2 min application time |
| 2% CHG 1 min | EXPERIMENTAL | single administration, 1 min application time |
| 2% CHG 2 min | EXPERIMENTAL | single administration, 2 min application time |
| 2% CHG 3 min | EXPERIMENTAL | single administration, 3 min application time |
| Comparator 2% CHG | ACTIVE_COMPARATOR | Single administration, Marketed CHG |
| Name | Type | Description |
|---|---|---|
| CHG | DRUG | Single application |
Inclusion Criteria: * Healthy * No dermatological conditions Exclusion Criteria: * Sensitivity to CHG * Sensitivity to natural latex rubber or adhesive skin products
CHG, or chlorhexidine gluconate, is an investigational small molecule being studied for use in healthy volunteers and in patients undergoing surgery. It is being evaluated as a preoperative skin preparation and for its antimicrobial efficacy. The drug is in Phase 1 clinical development.
CHG is being developed by Medline Inc., a company listed under the ticker MDLN. The drug is currently in Phase 1 clinical trials, with two completed studies involving a total of 41 participants.
CHG is in Phase 1 clinical development. It is an investigational drug, not yet approved by regulatory authorities. Two Phase 1 trials have been completed, both with active control groups, but the drug remains in early-stage testing.
CHG has been studied in three completed Phase 1 trials. These include NCT02530528, a pilot trial of preoperative CHG skin preparation in surgery patients; NCT02530541, evaluating antimicrobial efficacy in healthy volunteers; and NCT02530554, another pilot trial of preoperative skin preparation in surgery patients.
Yes, CHG is the same as chlorhexidine gluconate. The drug is referred to by its abbreviation CHG in clinical trial titles and descriptions, and it is being investigated for its antimicrobial properties in surgical skin preparation and in healthy individuals.